Surendra Prajapati
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View article: Artificial Intelligence in Cardiac Amyloidosis: A Systematic Review and Meta-Analysis of Diagnostic Accuracy Across Imaging and Non-Imaging Modalities
Artificial Intelligence in Cardiac Amyloidosis: A Systematic Review and Meta-Analysis of Diagnostic Accuracy Across Imaging and Non-Imaging Modalities Open
Introduction Cardiac amyloidosis (CA) is an underdiagnosed infiltrative cardiomyopathy associated with poor outcomes if not detected early. Artificial intelligence (AI) has emerged as a promising adjunct to conventional diagnostics, levera…
View article: Comparative Efficacy and Safety of Medical Treatments for Cushing’s Disease: A Systematic Review and Network Meta-Analysis
Comparative Efficacy and Safety of Medical Treatments for Cushing’s Disease: A Systematic Review and Network Meta-Analysis Open
Introduction Cushing’s disease (CD) is a rare endocrine disorder characterized by excessive cortisol production due to a pituitary adenoma secreting ACTH, leading to a range of systemic effects including obesity, hypertension, and hypergly…
View article: Endoscopic Endonasal Surgery for Pituitary Adenomas with Cavernous Sinus Invasion: A Comprehensive Meta-Analysis of Efficacy, Remission Rates, Surgical Outcomes, and Complications
Endoscopic Endonasal Surgery for Pituitary Adenomas with Cavernous Sinus Invasion: A Comprehensive Meta-Analysis of Efficacy, Remission Rates, Surgical Outcomes, and Complications Open
Introduction Pituitary adenomas with cavernous sinus invasion represent a challenging subset of intracranial tumors. The presence of cavernous sinus invasion complicates surgical resection and increases the risk of recurrence and postopera…
View article: Comparative Efficacy and Safety of GLP-1 Receptor Agonists in Neurological and Nephrological Outcomes of Type 2 Diabetes: A Systematic Review and Network Meta-Analysis
Comparative Efficacy and Safety of GLP-1 Receptor Agonists in Neurological and Nephrological Outcomes of Type 2 Diabetes: A Systematic Review and Network Meta-Analysis Open
Introduction Type 2 diabetes (T2D) is associated with significant neurological and nephrological complications, leading to high morbidity and mortality. GLP-1 receptor agonists (GLP-1 RAs), such as liraglutide, semaglutide, and tirzepatide…
View article: Clinical Outcomes of Salvage Nodal Radiotherapy for Prostate Cancer with Prior Radiotherapy
Clinical Outcomes of Salvage Nodal Radiotherapy for Prostate Cancer with Prior Radiotherapy Open
View article: Systematic Review and Meta-Analysis of Stem Cell Therapy in Myocardial Infarction: Effects on Left Ventricular Ejection Fraction and Major Adverse Cardiovascular Events
Systematic Review and Meta-Analysis of Stem Cell Therapy in Myocardial Infarction: Effects on Left Ventricular Ejection Fraction and Major Adverse Cardiovascular Events Open
Introduction Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality worldwide, often progressing to heart failure (HF) despite advances in treatment. Stem cell therapy has emerged as a promising approach to repair …
View article: Automatic contour quality assurance using deep-learning based contours
Automatic contour quality assurance using deep-learning based contours Open
Objective. Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One such approach is to use two independent auto-contouring models and compare them geometrically for acceptability. This is n…
View article: AAPM WGWMRSC Report 420: chapter climate check: Mixed methods analysis of survey responses
AAPM WGWMRSC Report 420: chapter climate check: Mixed methods analysis of survey responses Open
Introduction The American Association of Physicists in Medicine (AAPM) recently shared results and recommendations from its first Equity, Diversity, and Inclusion (EDI) Climate Survey, which was designed to assess the climate at the workpl…
View article: Chronic Kidney Disease Diagnosis Using Machine Learning
Chronic Kidney Disease Diagnosis Using Machine Learning Open
View article: MR‐Linac‐guided stereotactic radiotherapy for CT‐indiscernible intravascular renal cell carcinoma tumours
MR‐Linac‐guided stereotactic radiotherapy for CT‐indiscernible intravascular renal cell carcinoma tumours Open
View article: Analyzing the Relationship between Dose and Geometric Agreement Metrics for Auto-Contouring in Head and Neck Normal Tissues
Analyzing the Relationship between Dose and Geometric Agreement Metrics for Auto-Contouring in Head and Neck Normal Tissues Open
This study aimed to determine the relationship between geometric and dosimetric agreement metrics in head and neck (H&N) cancer radiotherapy plans. A total 287 plans were retrospectively analyzed, comparing auto-contoured and clinically us…
View article: Numerical optimization of longitudinal collimator geometry for novel x-ray field
Numerical optimization of longitudinal collimator geometry for novel x-ray field Open
Objective . A novel x-ray field produced by an ultrathin conical target is described in the literature. However, the optimal design for an associated collimator remains ambiguous. Current optimization methods using Monte Carlo calculations…
View article: Artificial Intelligence–Based Radiotherapy Contouring and Planning to Improve Global Access to Cancer Care
Artificial Intelligence–Based Radiotherapy Contouring and Planning to Improve Global Access to Cancer Care Open
PURPOSE Increased automation has been identified as one approach to improving global cancer care. The Radiation Planning Assistant (RPA) is a web-based tool offering automated radiotherapy (RT) contouring and planning to low-resource clini…
View article: Evaluation of Scrub Typhus Surveillance, Alwar District, Rajasthan, India, July-August 2020
Evaluation of Scrub Typhus Surveillance, Alwar District, Rajasthan, India, July-August 2020 Open
Introduction: Scrub typhus is one of the most underreported and fatal illnesses accounting for 23% of all febrile illness. Rajasthan reported cases during 2018–2019 in state reporting system but did not report any case to central Integrate…
View article: Characterization of the Plastic Scintillator Detector System Exradin W2 in a High Dose Rate Flattening-Filter-Free Photon Beam
Characterization of the Plastic Scintillator Detector System Exradin W2 in a High Dose Rate Flattening-Filter-Free Photon Beam Open
(1) Background: The Exradin W2 is a commercially available scintillator detector designed for reference and relative dosimetry in small fields. In this work, we investigated the performance of the W2 scintillator in a 10 MV flattening-filt…
View article: Clinical acceptability of fully automated external beam radiotherapy for cervical cancer with three different beam delivery techniques
Clinical acceptability of fully automated external beam radiotherapy for cervical cancer with three different beam delivery techniques Open
Purpose To fully automate CT‐based cervical cancer radiotherapy by automating contouring and planning for three different treatment techniques. Methods We automated three different radiotherapy planning techniques for locally advanced cerv…
View article: Automatic contouring QA method using a deep learning–based autocontouring system
Automatic contouring QA method using a deep learning–based autocontouring system Open
Purpose To determine the most accurate similarity metric when using an independent system to verify automatically generated contours. Methods A reference autocontouring system (primary system to create clinical contours) and a verification…
View article: Characterization and implementation of a miniature X-ray system for live cell microscopy
Characterization and implementation of a miniature X-ray system for live cell microscopy Open
View article: Phase II Trial Investigating Definitive Radiation Therapy in Lieu of Systemic Therapy for Oligometastatic Renal Cell Carcinoma
Phase II Trial Investigating Definitive Radiation Therapy in Lieu of Systemic Therapy for Oligometastatic Renal Cell Carcinoma Open
View article: Outcomes and Toxicities of Proton and Photon Radiation Therapy for Testicular Seminoma
Outcomes and Toxicities of Proton and Photon Radiation Therapy for Testicular Seminoma Open
Proton beam therapy for testicular seminoma resulted in excellent clinical outcomes and was associated with lower rates of acute diarrhea but higher rates of acute dermatitis. Proton beam therapy resulted in no in-field secondary malignanc…
View article: Transient Room Lighting for Ambient Light Multiphoton Microscopy
Transient Room Lighting for Ambient Light Multiphoton Microscopy Open
Laser scanning microscopy techniques such as confocal and multiphoton fluorescence microscopy have been widely adopted by the biological research community due to their ability to monitor intact specimens at high spatial and temporal resol…
View article: Local Control after 50 Gy Delivered in 5 Fractions Versus 10 Fractions for Primary and Metastatic Lung Tumors
Local Control after 50 Gy Delivered in 5 Fractions Versus 10 Fractions for Primary and Metastatic Lung Tumors Open
View article: Stereotactic body radiotherapy for an isolated splenic metastasis from ovarian carcinoma.
Stereotactic body radiotherapy for an isolated splenic metastasis from ovarian carcinoma. Open
Splenic metastases from oligometastatic ovarian carcinoma are a rare occurrence. Usual treatment for splenic metastases includes splenectomy, but some patients are either unable or unwilling to undergo surgery. Stereotactic body radiothera…