Eric Vaughn
YOU?
Author Swipe
View article: Molecular and neural control of social hierarchy by a forebrain-thalamocortical circuit
Molecular and neural control of social hierarchy by a forebrain-thalamocortical circuit Open
Many animal groups are organized hierarchically, which generates behavioral states that facilitate social interactions. Although generally stable, social status can change, underscoring the plasticity of underlying neural circuits. We exam…
View article: Control of feeding by a bottom-up midbrain-subthalamic pathway
Control of feeding by a bottom-up midbrain-subthalamic pathway Open
Investigative exploration and foraging leading to food consumption have vital importance, but are not well-understood. Since GABAergic inputs to the lateral and ventrolateral periaqueductal gray (l/vlPAG) control such behaviors, we dissect…
View article: Three-dimensional Interrogation of Cell Types and Instinctive Behavior in the Periaqueductal Gray
Three-dimensional Interrogation of Cell Types and Instinctive Behavior in the Periaqueductal Gray Open
Summary The periaqueductal gray (PAG) is a critical midbrain hub that relays information from the forebrain to motor and autonomic brainstem centers to orchestrate instinctive behaviors. The current organization of the PAG into four main r…
View article: A preoptic neuronal population controls fever and appetite during sickness
A preoptic neuronal population controls fever and appetite during sickness Open
View article: Nuclear isolation and sequencing for mouse hypothalamus v1
Nuclear isolation and sequencing for mouse hypothalamus v1 Open
This protocol is intended for isolation of nuclei from fresh brain tissue in preparation for single-nuclei sequencing library using Chromium Single Cell 3’ Reagent Kits v2 or v3 (10X Genomics). For each step, tissue and reagents were kept …
View article: Eric Vaughn snRNASeq Protocol v1
Eric Vaughn snRNASeq Protocol v1 Open
This protocol is designed to extract single nuclei for sequencing with 10X Genomics technologies. Note: For each step, keep tissue/nuclei/reagents/centrifuge on ice/cold to reduce IEG expression and maintain nuclear integrity. Buffers to p…
View article: Effect of Protocolized Post-Extubation Respiratory Support on Reintubation: A Randomized Clinical Trial
Effect of Protocolized Post-Extubation Respiratory Support on Reintubation: A Randomized Clinical Trial Open
View article: Molecular and Circuit Architecture of Social Hierarchy
Molecular and Circuit Architecture of Social Hierarchy Open
SUMMARY Social hierarchy is a common organizational structure of animal groups, in which an individual’s social status generates an adaptive behavioral state that facilitates interactions with other group members. Although generally stable…
View article: Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region
Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region Open
Mapping the brain, one neuron at a time Spatial transcriptomics can link molecularly described cell types to their anatomical positions and functional roles. Moffitt et al. used a combination of single-cell RNA-sequencing and MERFISH (mult…
View article: One Health Innovations Research Symposium: Preventing the Next Pandemic ConferenceAugust 27–28, 2017Kansas City Convention Center, Kansas City, MO
One Health Innovations Research Symposium: Preventing the Next Pandemic ConferenceAugust 27–28, 2017Kansas City Convention Center, Kansas City, MO Open
to offer a two-day symposium on key issues relating to one health research.This year's theme, ''Preventing the Next Pandemic'' features presentations from national and regional experts addressing the topic from two perspectives, predictive…
View article: A genetically engineered H5 protein expressed in insect cells confers protection against different clades of H5N1 highly pathogenic avian influenza viruses in chickens
A genetically engineered H5 protein expressed in insect cells confers protection against different clades of H5N1 highly pathogenic avian influenza viruses in chickens Open
The evolution of highly pathogenic H5N1 avian influenza viruses (HPAI-H5N1) has resulted in the appearance of a number of diverse groups of HPAI-H5N1 based on the presence of genetically similar clusters of their haemagglutinin sequences (…