Laurence M. Epstein
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View article: Long-Term Outcomes
Long-Term Outcomes Open
The findings of this large retrospective cohort study suggest that use of beta-blockers and permanent pacing are each associated with a lower risk of mortality in patients with HFpEF.
View article: Safety and Clinical Outcomes of Transvenous Lead Extraction for Cardiac Device Infections in the Very Elderly
Safety and Clinical Outcomes of Transvenous Lead Extraction for Cardiac Device Infections in the Very Elderly Open
Background The increasing use of cardiac implantable electronic devices (CIEDs) has led to a rise in transvenous lead extractions (TLE), particularly for device‐related infections. The elderly represent a growing subgroup undergoing TLE, b…
View article: One-Year Outcomes of the MODULAR ATP Trial: A Novel Leadless Pacemaker in Wireless Communication With a Subcutaneous Implantable Cardioverter Defibrillator
One-Year Outcomes of the MODULAR ATP Trial: A Novel Leadless Pacemaker in Wireless Communication With a Subcutaneous Implantable Cardioverter Defibrillator Open
BACKGROUND: MODULAR antitachycardia pacing (ATP), a multicenter, international trial, assesses a modular cardiac rhythm management system: a subcutaneous implantable cardioverter defibrillator in wireless communication with a leadless pace…
View article: Impact of timing of treatment for cardiac implantable electronic device infections on healthcare utilization and expenditures
Impact of timing of treatment for cardiac implantable electronic device infections on healthcare utilization and expenditures Open
Aims Early extraction for cardiovascular implantable electronic device (CIED) infections has been associated with longer survival, while the impact on healthcare utilization is unknown. The aim is to evaluate the impact of early extraction…
View article: Spontaneous arrhythmic episodes in the study of a modular, communicative, leadless pacing-defibrillator system (Modular ATP trial)
Spontaneous arrhythmic episodes in the study of a modular, communicative, leadless pacing-defibrillator system (Modular ATP trial) Open
Background MODULAR ATP, a multicenter, international trial, assesses a subcutaneous ICD (S-ICD) in wireless communication to a leadless pacemaker (LP) capable of pace terminating ventricular arrhythmias in addition to providing shock thera…
View article: Ten years of leadless pacing
Ten years of leadless pacing Open
Pacemakers are a lifesaving and mature technology. The past decade has seen a revolution in pacemaker technology with the development of leadless pacemakers. There is growing evidence for the value of leadless pacemakers in the management …
View article: Design of a post-market registry for the extravascular implantable cardioverter-defibrillator: The Enlighten Study
Design of a post-market registry for the extravascular implantable cardioverter-defibrillator: The Enlighten Study Open
NCT06048731.
View article: Performance and Safety of the Extravascular Implantable Cardioverter Defibrillator Through Long-Term Follow-Up: Final Results From the Pivotal Study
Performance and Safety of the Extravascular Implantable Cardioverter Defibrillator Through Long-Term Follow-Up: Final Results From the Pivotal Study Open
BACKGROUND: Substernal lead placement of the extravascular implantable cardioverter defibrillator (EV ICD) permits both defibrillation at thresholds similar to those seen with transvenous implantable cardioverter defibrillators and effecti…
View article: COVID‐19 vaccination and atrial fibrillation: When pandemics collide
COVID‐19 vaccination and atrial fibrillation: When pandemics collide Open
In the wake of the coronavirus disease 2019 (COVID-19) pandemic, accelerated research and development efforts were made to create a new class of vaccinations to mitigate the unprecedented global health burden. However, the rapid developmen…
View article: Ventricular tachycardia due to delayed septal perforation by a left bundle branch area pacing lead
Ventricular tachycardia due to delayed septal perforation by a left bundle branch area pacing lead Open
Right ventricular pacing with a dual chamber transvenous pacemaker has historically been used in patients with preserved left ventricular systolic function and atrioventricular block. Pacing from the right ventricle is associated with incr…
View article: Lead Extraction and Mortality Among Patients With Cardiac Implanted Electronic Device Infection
Lead Extraction and Mortality Among Patients With Cardiac Implanted Electronic Device Infection Open
Importance Complete hardware removal is a class I recommendation for cardiovascular implantable electronic device (CIED) infection, but practice patterns and outcomes remain unknown. Objective To quantify the number of Medicare patients wi…
View article: Lead management in patients undergoing percutaneous tricuspid valve replacement or repair: a ‘heart team’ approach
Lead management in patients undergoing percutaneous tricuspid valve replacement or repair: a ‘heart team’ approach Open
Clinically significant tricuspid regurgitation (TR) has historically been managed with either medical therapy or surgical interventions. More recently, percutaneous trans-catheter tricuspid valve (TV) replacement and tricuspid trans-cathet…
View article: Safety and success of transvenous lead extraction using excimer laser sheaths: a meta-analysis of over 1700 patients
Safety and success of transvenous lead extraction using excimer laser sheaths: a meta-analysis of over 1700 patients Open
Aims While numerous studies have demonstrated favourable safety and efficacy of the excimer laser sheath for transvenous lead extraction (TLE) in smaller cohorts, comprehensive large-scale investigations with contemporary data remain scarc…
View article: High success and safety of transvenous lead extraction using excimer laser sheaths in more than 1700 patients: a meta-analysis
High success and safety of transvenous lead extraction using excimer laser sheaths in more than 1700 patients: a meta-analysis Open
Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Philips Background The excimer laser sheath is a commonly used advanced transvenous lead extraction (TLE) tool to aid the successful extraction of i…