Monica M. Farley
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View article: The epidemiology of bacterial meningitis in the United States during 2008–2023: an analysis of active, laboratory, population-based, multistate surveillance data
The epidemiology of bacterial meningitis in the United States during 2008–2023: an analysis of active, laboratory, population-based, multistate surveillance data Open
View article: Comparative genomic analysis of emerging non-typeable <i>Haemophilus influenzae</i> (NTHi) causing emerging septic arthritis in Atlanta
Comparative genomic analysis of emerging non-typeable <i>Haemophilus influenzae</i> (NTHi) causing emerging septic arthritis in Atlanta Open
Background Haemophilus influenzae is a Gram-negative bacterium that can exist as a commensal organism or cause a range of diseases, from ear infections to invasive conditions like meningitis. While encapsulated H. influenzae strains have h…
View article: Serotype-specific pneumococcal invasiveness: a global meta-analysis of paired estimates of disease incidence and carriage prevalence
Serotype-specific pneumococcal invasiveness: a global meta-analysis of paired estimates of disease incidence and carriage prevalence Open
Background Serotype-specific estimates of pneumococcal invasiveness used in pneumococcal carriage transmission models to predict changes in disease incidence post-vaccination are largely derived from high-income settings. We conducted a sy…
View article: P-1329. Invasive Streptococcal Infections in People Experiencing Homelessness in Metro Atlanta — Fulton, DeKalb, and Cobb County, Georgia, 2010–2022
P-1329. Invasive Streptococcal Infections in People Experiencing Homelessness in Metro Atlanta — Fulton, DeKalb, and Cobb County, Georgia, 2010–2022 Open
Background People experiencing homelessness (PEH) are disproportionately affected by infectious diseases compared to people who are housed (non-PEH). In the western U.S., 9–25% of invasive pneumococcal disease (IPD) and group A Streptococc…
View article: Erratum for Misas et al., “Genomic description of acquired fluconazole- and echinocandin-resistance in patients with serial <i>Candida glabrata</i> isolates”
Erratum for Misas et al., “Genomic description of acquired fluconazole- and echinocandin-resistance in patients with serial <i>Candida glabrata</i> isolates” Open
Volume 62, no. 2, e01140-23, https://doi.org/10.1128/jcm.01140-23. In the abstract, "Of the 24 fluconazole-resistant isolates, 17 (71%) had non-synonymous polymorphisms" should read "Of the 25 fluconazole-resistant isolates, 16 (64%) had n…
View article: Molecular and Epidemiological Investigation of Fluconazole-resistant <i>Candida parapsilosis</i>—Georgia, United States, 2021
Molecular and Epidemiological Investigation of Fluconazole-resistant <i>Candida parapsilosis</i>—Georgia, United States, 2021 Open
Background Reports of fluconazole-resistant Candida parapsilosis bloodstream infections are increasing. We describe a cluster of fluconazole-resistant C parapsilosis bloodstream infections identified in 2021 on routine surveillance by the …
View article: Effectiveness of 13-valent pneumococcal conjugate vaccine for prevention of invasive pneumococcal disease among children in the United States between 2010 and 2019: An indirect cohort study
Effectiveness of 13-valent pneumococcal conjugate vaccine for prevention of invasive pneumococcal disease among children in the United States between 2010 and 2019: An indirect cohort study Open
View article: Genomic description of acquired fluconazole- and echinocandin-resistance in patients with serial <i>Candida glabrata</i> isolates
Genomic description of acquired fluconazole- and echinocandin-resistance in patients with serial <i>Candida glabrata</i> isolates Open
In our study, mutations associated to azole resistance and echinocandin resistance were detected in Candida glabrata isolates using a whole-genome sequence. C. glabrata is the second most common cause of candidemia in the United States, wh…
View article: Immunogenicity and Safety of Meningococcal&nbsp;ACWYX Conjugate Vaccine When Coadministered with Routine Childhood Vaccines at 9-Months and 15-Months of Age: A Randomised, Controlled, Phase 3, Non-Inferiority Trial
Immunogenicity and Safety of Meningococcal ACWYX Conjugate Vaccine When Coadministered with Routine Childhood Vaccines at 9-Months and 15-Months of Age: A Randomised, Controlled, Phase 3, Non-Inferiority Trial Open
View article: 1718. Effectiveness of 13-valent pneumococcal conjugate vaccine for prevention of invasive pneumococcal disease among children in the United States between 2010 and 2019: an indirect cohort study
1718. Effectiveness of 13-valent pneumococcal conjugate vaccine for prevention of invasive pneumococcal disease among children in the United States between 2010 and 2019: an indirect cohort study Open
Background The 13-valent pneumococcal conjugate vaccine (PCV13) was introduced for infant use in the United States in 2010, replacing PCV7. A U.S. case-control study (2010–2014) demonstrated vaccine effectiveness (VE) for ≥1 dose of PCV13 …
View article: 1281. Ongoing Transmission of Clonal Strains of Invasive Nontypeable <i>Haemophilus influenzae</i> Disproportionately Affecting Persons with HIV in Metropolitan Atlanta, 2019—2022
1281. Ongoing Transmission of Clonal Strains of Invasive Nontypeable <i>Haemophilus influenzae</i> Disproportionately Affecting Persons with HIV in Metropolitan Atlanta, 2019—2022 Open
Background Nontypeable Haemophilus influenzae (NTHi) is a genetically diverse pathogen that typically causes mucosal infections or invasive NTHi (iNTHi) disease in persons at the extremes of age. In 2017-2018, we reported a significant inc…
View article: 2885. Increased incidence of fluconazole-resistant <i>Candida parapsilosis</i> bloodstream infections in Atlanta, Georgia 2021
2885. Increased incidence of fluconazole-resistant <i>Candida parapsilosis</i> bloodstream infections in Atlanta, Georgia 2021 Open
Background Since 2020, outbreaks of fluconazole-resistant Candida parapsilosis (FR-CP) infections have proliferated around the world. An increase in FR-CP bloodstream infections (BSI) in the Atlanta metropolitan area in 2021 was identified…
View article: Evaluation of Asymptomatic <i>Bordetella</i> Carriage in a Convenience Sample of Children and Adolescents in Atlanta, Georgia, United States
Evaluation of Asymptomatic <i>Bordetella</i> Carriage in a Convenience Sample of Children and Adolescents in Atlanta, Georgia, United States Open
Few data exist on asymptomatic carriage of Bordetella species among populations receiving acellular pertussis vaccine. We conducted a cross-sectional study among acellular-vaccinated children presenting to an emergency department (ED). Bor…
View article: Estimated Effectiveness of JYNNEOS Vaccine in Preventing Mpox: A Multijurisdictional Case-Control Study — United States, August 19, 2022–March 31, 2023
Estimated Effectiveness of JYNNEOS Vaccine in Preventing Mpox: A Multijurisdictional Case-Control Study — United States, August 19, 2022–March 31, 2023 Open
As of March 31, 2023, more than 30,000 monkeypox (mpox) cases had been reported in the United States in an outbreak that has disproportionately affected gay, bisexual, and other men who have sex with men (MSM) and transgender persons (1). …
View article: Changes in the Incidence of Invasive Bacterial Disease During the COVID-19 Pandemic in the United States, 2014–2020
Changes in the Incidence of Invasive Bacterial Disease During the COVID-19 Pandemic in the United States, 2014–2020 Open
Background Descriptions of changes in invasive bacterial disease (IBD) epidemiology during the coronavirus disease 2019 (COVID-19) pandemic in the United States are limited. Methods We investigated changes in the incidence of IBD due to St…
View article: Epidemiology of Invasive Nontypeable <i>Haemophilus influenzae</i> Disease<i>—</i>United States, 2008–2019
Epidemiology of Invasive Nontypeable <i>Haemophilus influenzae</i> Disease<i>—</i>United States, 2008–2019 Open
Background Nontypeable Haemophilus influenzae (NTHi) is the most common cause of invasive H. influenzae disease in the United States (US). We evaluated the epidemiology of invasive NTHi disease in the US, including among pregnant women, in…
View article: 416. Evaluating Indwelling Devices and Mortality in Invasive Carbapenem-Resistant Enterobacterales Infections, Atlanta, GA, 2012–2019.
416. Evaluating Indwelling Devices and Mortality in Invasive Carbapenem-Resistant Enterobacterales Infections, Atlanta, GA, 2012–2019. Open
Background Carbapenem-resistant Enterobacterales (CRE) infections pose a grave public health threat due to the potentially silent transmission leading to outbreaks, limited therapeutic options and high mortality. We sought to identify risk…
View article: Recurrent Candidemia: Trends and Risk Factors Among Persons Residing in 4 US States, 2011–2018
Recurrent Candidemia: Trends and Risk Factors Among Persons Residing in 4 US States, 2011–2018 Open
Background Candidemia is a common healthcare-associated infection with high mortality. Estimates of recurrence range from 1% to 17%. Few studies have focused on those with recurrent candidemia, who often experience more severe illness and …
View article: Use of 15-Valent Pneumococcal Conjugate Vaccine Among U.S. Children: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2022
Use of 15-Valent Pneumococcal Conjugate Vaccine Among U.S. Children: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2022 Open
The 13-valent pneumococcal conjugate vaccine (PCV13 [Prevnar 13, Wyeth Pharmaceuticals, Inc, a subsidiary of Pfizer, Inc]) and the 23-valent pneumococcal polysaccharide vaccine (PPSV23 [Merck Sharp & Dohme LLC]) have been recommended for U…
View article: Low Sensitivity of <i>International Classification of Diseases, Tenth Revision</i> Coding for Culture-Confirmed Candidemia Cases in an Active Surveillance System: United States, 2019–2020
Low Sensitivity of <i>International Classification of Diseases, Tenth Revision</i> Coding for Culture-Confirmed Candidemia Cases in an Active Surveillance System: United States, 2019–2020 Open
We evaluated healthcare facility use of International Classification of Diseases, Tenth Revision (ICD-10) codes for culture-confirmed candidemia cases detected by active public health surveillance during 2019–2020. Most cases (56%) did not…
View article: Phylogenomic Comparison of <i>Neisseria gonorrhoeae</i> Causing Disseminated Gonococcal Infections and Uncomplicated Gonorrhea in Georgia, United States
Phylogenomic Comparison of <i>Neisseria gonorrhoeae</i> Causing Disseminated Gonococcal Infections and Uncomplicated Gonorrhea in Georgia, United States Open
Disseminated gonococcal infection (DGI) is a rare complication caused by the systemic dissemination of Neisseria gonorrhoeae to normally sterile anatomical sites. Little is known about the genetic diversity of DGI gonococcal strains and ho…
View article: Impact of Pneumococcal Conjugate Vaccines on Antibiotic-Nonsusceptible Invasive Pneumococcal Disease in the United States
Impact of Pneumococcal Conjugate Vaccines on Antibiotic-Nonsusceptible Invasive Pneumococcal Disease in the United States Open
Background Antibiotic-nonsusceptible invasive pneumococcal disease (NS-IPD) incidence declined dramatically in the United States after introduction of pneumococcal conjugate vaccines (PCVs) into the infant immunization schedule (7-valent P…
View article: Clinical Characteristics, Health Care Utilization, and Outcomes Among Patients in a Pilot Surveillance System for Invasive Mold Disease—Georgia, United States, 2017–2019
Clinical Characteristics, Health Care Utilization, and Outcomes Among Patients in a Pilot Surveillance System for Invasive Mold Disease—Georgia, United States, 2017–2019 Open
Background Invasive mold diseases (IMDs) cause severe illness, but public health surveillance data are lacking. We describe data collected from a laboratory-based, pilot IMD surveillance system. Methods During 2017–2019, the Emerging Infec…
View article: Surveillance for Disseminated Gonococcal Infections, Active Bacterial Core Surveillance (ABCs)—United States, 2015–2019
Surveillance for Disseminated Gonococcal Infections, Active Bacterial Core Surveillance (ABCs)—United States, 2015–2019 Open
Background Disseminated gonococcal infections (DGIs) are thought to be uncommon; surveillance is limited, and case reports are analyzed retrospectively or in case clusters. We describe the population-level burden of culture-confirmed DGIs …
View article: Risk Factors for Invasive Meningococcal Disease Belonging to a Novel Urethritis Clade of <i>Neisseria meningitidis</i>—United States, 2013–2017
Risk Factors for Invasive Meningococcal Disease Belonging to a Novel Urethritis Clade of <i>Neisseria meningitidis</i>—United States, 2013–2017 Open
We describe cases of invasive meningococcal disease caused by nongroupable Neisseria meningitidis belonging to a novel phylogenetic clade associated with urethritis. Seven cases were identified, comprising 0.6% of sequenced invasive mening…
View article: 1299. Epidemiology of Invasive Pneumococcal Disease (IPD) in the United States 2011-2019
1299. Epidemiology of Invasive Pneumococcal Disease (IPD) in the United States 2011-2019 Open
Background Thirteen-valent pneumococcal conjugate vaccine (PCV13) was recommended for U.S. children aged < 5 years in February 2010 and recommended in series with 23-valent pneumococcal polysaccharide vaccine (PPSV23) for adults aged ≥ …
View article: 70. Changes in Invasive Pneumococcal Disease among Adults Living with HIV Following Introduction of 13-Valent Pneumococcal Conjugate Vaccine, 2008–2018
70. Changes in Invasive Pneumococcal Disease among Adults Living with HIV Following Introduction of 13-Valent Pneumococcal Conjugate Vaccine, 2008–2018 Open
Background People living with HIV (PLHIV) are at increased risk of invasive pneumococcal disease (IPD). The 13-valent pneumococcal conjugate vaccine (PCV13) was recommended for children in 2010, and for immunocompromised adults (including …
View article: Brucellosis Initially Misidentified as <i>Ochrobactrum anthropi</i> Bacteremia: A Case Report and Review of the Literature
Brucellosis Initially Misidentified as <i>Ochrobactrum anthropi</i> Bacteremia: A Case Report and Review of the Literature Open
Automated identification systems may misidentify Brucella, the causative agent of brucellosis, which may be re-emerging in the United States as the result of an expanding feral swine population. We present a case of Brucella suis likely as…
View article: Effectiveness of COVID-19 Vaccines in Preventing Hospitalization Among Adults Aged ≥65 Years — COVID-NET, 13 States, February–April 2021
Effectiveness of COVID-19 Vaccines in Preventing Hospitalization Among Adults Aged ≥65 Years — COVID-NET, 13 States, February–April 2021 Open
Clinical trials of COVID-19 vaccines currently authorized for emergency use in the United States (Pfizer-BioNTech, Moderna, and Janssen [Johnson & Johnson]) indicate that these vaccines have high efficacy against symptomatic disease, inclu…
View article: ICE volume 42 issue 8 Cover and Front matter
ICE volume 42 issue 8 Cover and Front matter Open
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