M Gembicki
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View article: Neonatal Outcome After Expectant Management of Preterm Premature Rupture of Membranes (PPROM) Between 34+0 and 36+6 Weeks of Gestation: A Single-Center Cohort Study
Neonatal Outcome After Expectant Management of Preterm Premature Rupture of Membranes (PPROM) Between 34+0 and 36+6 Weeks of Gestation: A Single-Center Cohort Study Open
Expectant management appears to be a viable and potentially safe approach for managing cases of PPROM between 34+0 and 36+6 weeks of gestation, without significantly increasing the risk of adverse neonatal outcome. However, close monitorin…
View article: Advantages of fully automated AI-enhanced algorithm (5D CNS+™) for generating a fetal neurosonogram in clinical routine
Advantages of fully automated AI-enhanced algorithm (5D CNS+™) for generating a fetal neurosonogram in clinical routine Open
Objectives The objective was to demonstrate superiority of a fully vs. semi-automated approach (5D CNS+™) and to verify operators could handle and benefit from a fully automated rendering volumetric datasets to generate a complete fetal ne…
View article: Perinatal Antibiotic Exposure and Respiratory Outcomes in Children Born Preterm
Perinatal Antibiotic Exposure and Respiratory Outcomes in Children Born Preterm Open
Importance Animal models suggest a link between early antibiotic exposure and obstructive airway disease, but corresponding data for premature infants are lacking. Objective To investigate whether repeated perinatal antibiotic exposure in …
View article: Effects of multistrain Bifidobacteria and Lactobacillus probiotics on HMO compositions after supplementation to pregnant women at threatening preterm delivery: design of the randomized clinical PROMO trial
Effects of multistrain Bifidobacteria and Lactobacillus probiotics on HMO compositions after supplementation to pregnant women at threatening preterm delivery: design of the randomized clinical PROMO trial Open
Background As an indigestible component of human breast milk, Human Milk Oligosaccharides (HMOs) play an important role as a substrate for the establishing microbiome of the newborn. They have further been shown to have beneficial effects …
View article: How automated techniques ease functional assessment of the fetal heart: Applicability of two‐dimensional speckle‐tracking echocardiography for comprehensive analysis of global and segmental cardiac deformation using fetalHQ®
How automated techniques ease functional assessment of the fetal heart: Applicability of two‐dimensional speckle‐tracking echocardiography for comprehensive analysis of global and segmental cardiac deformation using fetalHQ® Open
Background Prenatal echocardiographic assessment of fetal cardiac function has become increasingly important. Fetal two‐dimensional speckle‐tracking echocardiography (2D‐STE) allows the determination of global and segmental functional card…
View article: How automated techniques ease functional assessment of the fetal heart: applicability of two-dimensional speckle-tracking echocardiography for comprehensive analysis of global and segmental cardiac deformation using fetalHQ®
How automated techniques ease functional assessment of the fetal heart: applicability of two-dimensional speckle-tracking echocardiography for comprehensive analysis of global and segmental cardiac deformation using fetalHQ® Open
Background Prenatal echocardiographic assessment of fetal cardiac function has become increasingly important. Fetal two-dimensional speckle-tracking echocardiography (2D-STE) allows the determination of global and segmental functional card…
View article: Semi-Automatic Measurement of Fetal Cardiac Axis in Fetuses with Congenital Heart Disease (CHD) with Fetal Intelligent Navigation Echocardiography (FINE)
Semi-Automatic Measurement of Fetal Cardiac Axis in Fetuses with Congenital Heart Disease (CHD) with Fetal Intelligent Navigation Echocardiography (FINE) Open
Congenital heart disease (CHD) is one of the most common organ-specific birth defects and a major cause of infant morbidity and mortality. Despite ultrasound screening guidelines, the detection rate of CHD is limited. Fetal intelligent nav…
View article: EP24.34: Improvement of ultrasound‐based diagnosis in fetal conotruncal anomalies in a tertiary referral centre in 30 years
EP24.34: Improvement of ultrasound‐based diagnosis in fetal conotruncal anomalies in a tertiary referral centre in 30 years Open
To analyse if the gestational age of first diagnosis of fetal conotruncal anomalies (CTA) improves over a period of three decades (from 1993 until 2022) in a tertiary referral centre. We conducted a retrospective study in a single tertiary…
View article: EP01.33: Is fetal LV and RV non‐compaction a cardiac condition potentially diagnosed even in low‐risk pregnancies: thoughts on under‐ and overestimation
EP01.33: Is fetal LV and RV non‐compaction a cardiac condition potentially diagnosed even in low‐risk pregnancies: thoughts on under‐ and overestimation Open
Objectives: Considering the fact that it remains not clear whether ventricular non-compaction constitutes a separate cardiomyopathy or rather a morphological trait shared by many phenotypically distinct cardiomyopathies, or even present in…
View article: A Clinical Approach to Semiautomated Three-Dimensional Fetal Brain Biometry—Comparing the Strengths and Weaknesses of Two Diagnostic Tools: 5DCNS+TM and SonoCNSTM
A Clinical Approach to Semiautomated Three-Dimensional Fetal Brain Biometry—Comparing the Strengths and Weaknesses of Two Diagnostic Tools: 5DCNS+TM and SonoCNSTM Open
(1) Objective: We aimed to evaluate the accuracy and efficacy of AI-assisted biometric measurements of the fetal central nervous system (CNS) by comparing two semiautomatic postprocessing tools. We further aimed to discuss the additional v…
View article: How Automated Techniques Ease Functional Assessment of the Fetal Heart: Applicability of MPI+™ for Direct Quantification of the Modified Myocardial Performance Index
How Automated Techniques Ease Functional Assessment of the Fetal Heart: Applicability of MPI+™ for Direct Quantification of the Modified Myocardial Performance Index Open
(1) Objectives: In utero functional cardiac assessments using echocardiography have become increasingly important. The myocardial performance index (MPI, Tei index) is currently used to evaluate fetal cardiac anatomy, hemodynamics and func…
View article: Application of Semiautomatic Fetal Intelligent Navigation Echocardiography (FINE) in Twin Pregnancies: Half the Work or Twice the Effort?
Application of Semiautomatic Fetal Intelligent Navigation Echocardiography (FINE) in Twin Pregnancies: Half the Work or Twice the Effort? Open
Our results indicate that the FINE technique used in twin pregnancies is reliable. No significant difference between the depiction rates of twin 1 and twin 2 could be detected. In addition, the depiction rates are as high as those derived …
View article: Vascular Choroidal Alterations in Uncomplicated Third-Trimester Pregnancy
Vascular Choroidal Alterations in Uncomplicated Third-Trimester Pregnancy Open
(1) Purpose: To evaluate the anatomy and perfusion of choroidal substructures in third-trimester pregnant women using optical coherence tomography (OCT) and OCT angiography (OCTA) imaging. (2) Methods: In this cross-sectional study, women …
View article: Applicability of a semiautomated volumetric approach (5D CNS+™) for detailed antenatal reconstruction of abnormal fetal CNS anatomy
Applicability of a semiautomated volumetric approach (5D CNS+™) for detailed antenatal reconstruction of abnormal fetal CNS anatomy Open
Background The aim of this study was to evaluate the accuracy and reliability of a semiautomated volumetric approach (5D CNS+™) when examining fetuses with an apparent abnormal anatomy of the central nervous system (CNS). Methods Stored 3D…
View article: Maximal Reduction of STIC Acquisition Time for Volumetric Assessment of the Fetal Heart—Benefits and Limitations of Semiautomatic Fetal Intelligent Navigation Echocardiography (FINE) Static Mode
Maximal Reduction of STIC Acquisition Time for Volumetric Assessment of the Fetal Heart—Benefits and Limitations of Semiautomatic Fetal Intelligent Navigation Echocardiography (FINE) Static Mode Open
(1) Objective: To scrutinize the reliability and the clinical value of routinely used fetal intelligent navigation echocardiography (FINE) static mode (5DHeartStatic™) for accelerated semiautomatic volumetric assessment of the normal fetal…
View article: <i>La Machine</i>: Obstetric Phantoms of Madame Du Coudray <i>… Back to the Roots</i>
<i>La Machine</i>: Obstetric Phantoms of Madame Du Coudray <i>… Back to the Roots</i> Open
For 300 years now, obstetrics has drawn on the concept of simulation training to not only teach anatomy and physiology theoretically, but to literally infuse it practically. In an 18 th century scientific culture, which was predominantly p…
View article: The Use of Artificial Intelligence in Automation in the Fields of Gynaecology and Obstetrics – an Assessment of the State of Play
The Use of Artificial Intelligence in Automation in the Fields of Gynaecology and Obstetrics – an Assessment of the State of Play Open
The long-awaited progress in digitalisation is generating huge amounts of medical data every day, and manual analysis and targeted, patient-oriented evaluation of this data is becoming increasingly difficult or even infeasible. This state …
View article: Applicability of a Semiautomated Volumetric Approach (5D CNS+™) for Detailed Antenatal Reconstruction of Abnormal Fetal CNS Anatomy
Applicability of a Semiautomated Volumetric Approach (5D CNS+™) for Detailed Antenatal Reconstruction of Abnormal Fetal CNS Anatomy Open
Background. The aim of this study was to evaluate the accuracy and reliability of a semiautomated volumetric approach (5DCNS+) when examining fetuses with an apparent abnormal anatomy of the central nervous system (CNS). Methods. Stored 3D…
View article: Lymphangioma of the fetal neck within the PIK3CA‐related‐overgrowth spectrum (PROS): A case report
Lymphangioma of the fetal neck within the PIK3CA‐related‐overgrowth spectrum (PROS): A case report Open
The delineation of the prenatal diagnostic key features of PIK3CA‐related overgrowth spectrum disorders will assume a crucial part in future and a prenatal diagnosis of the causing mutations would provide physicians with a simplified inter…
View article: Semiautomatic Assessment of Fetal Fractional Limb Volume for Weight Prediction in Clinical Praxis
Semiautomatic Assessment of Fetal Fractional Limb Volume for Weight Prediction in Clinical Praxis Open
Objectives Semiautomatic fractional limb volume (FLV) models have recently produced promising results for fetal birth weight (BW) estimation. We tested those models in a more unselected population hypothesizing that the FLV models would im…
View article: Lymphangioma of the fetal neck within the PIK3CA-Related-Overgrowth Spectrum (PROS): A case report.
Lymphangioma of the fetal neck within the PIK3CA-Related-Overgrowth Spectrum (PROS): A case report. Open
Neck tumors are rare fetal conditions. They can receive their growth stimuli by activating missense mutations characterizing disorders with benign overgrowth, collectively known as PIK3CA-Related-Overgrowth-Spectrum. This results in segmen…
View article: VP04.01: High‐resolution ultrasound in malformed first trimester fetuses with fetoscopic correlation: a single centre case series
VP04.01: High‐resolution ultrasound in malformed first trimester fetuses with fetoscopic correlation: a single centre case series Open
In this study we are reporting a series of malformed first-trimester fetuses which have been diagnosed by high-resolution ultrasound and confirmed by fetoscopy. In 20 cases of sonographically diagnosed severe malformations in the first tri…
View article: VP15.03: Comprehensive analysis of fetal cardiac volumes using 5DHeartStatic: advantages of a maximally diminished acquisition time
VP15.03: Comprehensive analysis of fetal cardiac volumes using 5DHeartStatic: advantages of a maximally diminished acquisition time Open
To scrutinise the reliability and clinical value of routinely used 5DHeartStatic tool for semiautomised volumetric assessment of the normal fetal heart. In this prospective cohort study we examined a total of 205 fetuses during 2nd and 3rd…
View article: Feasibility of Semiautomatic Fetal Intelligent Navigation Echocardiography for Different Fetal Spine Positions
Feasibility of Semiautomatic Fetal Intelligent Navigation Echocardiography for Different Fetal Spine Positions Open
Objectives We investigated the feasibility of a semiautomatic approach for assessments of the fetal heart (fetal intelligent navigation echocardiography [FINE]) in cases of optimal and unfavorable fetal spine positions. Methods In this stu…
View article: OP06.09: Cornelia de Lange syndrome amenable to early prenatal diagnosis? Lessons from 106 affected fetuses
OP06.09: Cornelia de Lange syndrome amenable to early prenatal diagnosis? Lessons from 106 affected fetuses Open
To evaluate current practice and diagnostic challenges towards an early prenatal detection of Cornelia de Lange syndrome (CdLS). In this retrospective analysis prenatal records of 8 fetuses of CdLS were analysed and compared with 98 previo…
View article: OP11.03: Semi‐automatic assessment of fetal cardiac axis using FINE method: one step further for optimised detection of congenital heart disease
OP11.03: Semi‐automatic assessment of fetal cardiac axis using FINE method: one step further for optimised detection of congenital heart disease Open
To scrutinise the validity of cardiac axis assessment using a semi-automised volumetric approach in a routine clinical setting. In this retrospective cohort study we enrolled 1.730 volume data sets of 1st, 2nd and 3rd trimester pregnancies…