M Giannotti Santoro
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View article: LAT velocity vectors: a novel tool for ventricular functional substrate characterization
LAT velocity vectors: a novel tool for ventricular functional substrate characterization Open
Background Catheter ablation is a cornerstone treatment for scar-related ventricular arrhythmias arising in patients affected by structural heart disease. LAT Velocity Vectors (LVV) is a novel feature for wave velocity visualization over v…
View article: Safety, workflow, and efficacy of atrial fibrillation ablation in women: pulsed field vs conventional thermal ablation
Safety, workflow, and efficacy of atrial fibrillation ablation in women: pulsed field vs conventional thermal ablation Open
Background Women are typically underrepresented in randomized clinical trials, including those focused on atrial fibrillation (AF). The efficacy and safety of pulsed field ablation (PFA) compared to conventional thermal ablation in women h…
View article: Three-dimensional characterization of ventricular arrhythmias in structural heart disease with a novel digital twin framework
Three-dimensional characterization of ventricular arrhythmias in structural heart disease with a novel digital twin framework Open
Background Catheter ablation is a cornerstone treatment for scar-related ventricular arrhythmias arising in patients affected by structural heart disease. Catheter mapping, even when high-density, only allows two-dimensional circuit charac…
View article: The Diagnostic Yield of Implantable Loop Recorders Stratified by Indication: A “Real-World” Single-Center Experience
The Diagnostic Yield of Implantable Loop Recorders Stratified by Indication: A “Real-World” Single-Center Experience Open
Background/Objectives: Implantable loop recorders (ILRs) are widely used for the diagnosis of unexplained syncope, palpitations, and cryptogenic stroke. While ILRs demonstrate clinical utility, data on their diagnostic yield and value in r…
View article: Ventricular arrhythmia events in patients with implantable cardioverter-defibrillator before and after the treatment with sodium-glucose co-transporter 2 inhibitors
Ventricular arrhythmia events in patients with implantable cardioverter-defibrillator before and after the treatment with sodium-glucose co-transporter 2 inhibitors Open
Background The role of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in the treatment of chronic heart failure is expanding. However, the timing of implantable cardioverter-defibrillator (ICD) implantation for primary prevention in r…
View article: NON–INVASIVE ASSESSMENT OF CARDIAC HEMODYNAMICS BY BIO–IMPEDANCE IN A PATIENT WITH HEART FAILURE AND EXCELLENT RESPONSE TO CARDIAC RESYNCHRONIZATION THERAPY
NON–INVASIVE ASSESSMENT OF CARDIAC HEMODYNAMICS BY BIO–IMPEDANCE IN A PATIENT WITH HEART FAILURE AND EXCELLENT RESPONSE TO CARDIAC RESYNCHRONIZATION THERAPY Open
Patient Presentation We present a 78–year–old patient admitted to our Cardiology Unit for chronic heart failure with severe left ventricular dysfunction, atrial fibrillation, and recent percutaneous aortic valve replacement and an NYHA IIb…
View article: VENTRICULAR ARRHYTHMIA EVENTS IN PATIENTS WITH IMPLANTABLE CARDIOVERTER–DEFIBRILLATOR BEFORE AND AFTER THE TREATMENT WITH SODIUM–GLUCOSE CO–TRANSPORTER 2 INHIBITORS
VENTRICULAR ARRHYTHMIA EVENTS IN PATIENTS WITH IMPLANTABLE CARDIOVERTER–DEFIBRILLATOR BEFORE AND AFTER THE TREATMENT WITH SODIUM–GLUCOSE CO–TRANSPORTER 2 INHIBITORS Open
Background Role of sodium–glucose co–transporter 2 inhibitors (SGLT2i) in the treatment of chronic heart failure is increasing. However, some case series described appropriate shocks from ICD in patients following the initiations of SGLT2i…
View article: Short and Long-Term Outcomes of Lesion Index-Guided High-Power Short-Duration Approach for Atrial Fibrillation Ablation
Short and Long-Term Outcomes of Lesion Index-Guided High-Power Short-Duration Approach for Atrial Fibrillation Ablation Open
High-power short-duration (HPSD) ablation is an increasingly used ablation strategy for pulmonary vein isolation (PVI) procedures, but Lesion Index (LSI)-guided HPSD radiofrequency (RF) applications have not been described in this clinical…
View article: Non-continuous mobile electrocardiogram monitoring for post-transcatheter aortic valve replacement delayed conduction disorders put to the test
Non-continuous mobile electrocardiogram monitoring for post-transcatheter aortic valve replacement delayed conduction disorders put to the test Open
Aims Permanent pacemaker implantation (PPM-I) remains nowadays the most important drawback of transcatheter aortic valve replacement (TAVR) procedure and the optimal strategy of delayed conduction disturbances (CDs) in these patients is un…
View article: Transvenous removal of pacing and ICD leads: single Italian referral center experience
Transvenous removal of pacing and ICD leads: single Italian referral center experience Open
Introduction Device related complications are rising the need of Transvenous Lead Removal (TLR). Transvenous extraction of Pacing (PL) and Defibrillating Leads (DL) is a highly effective technique. Aim of this report is to analyse the long…
View article: High density catheter approach with liveview dynamic display improves procedural efficiency of atrial fibrillation ablation
High density catheter approach with liveview dynamic display improves procedural efficiency of atrial fibrillation ablation Open
Introduction PVI isolation confirmation after RF ablation is often time-consuming, especially in case of a single transeptal catheter approach into the left atrium. A novel Live View (LV) dynamic display mapping software, utilized in combi…
View article: Cardiac arrhythmias and conduction disorders monitoring after transcatheter aortic valve replacement procedure, using a mobile electrocardiogram 6 lead device
Cardiac arrhythmias and conduction disorders monitoring after transcatheter aortic valve replacement procedure, using a mobile electrocardiogram 6 lead device Open
Background In the early post transcatheter aortic valve replacement (TAVR) discharge era, rate of readmission for permanent pacemaker implantation (PPM-I) due to delayed conduction disturbances (CDs) has significantly increased. This issue…
View article: Never too old for something new: feasibility and long-term outcomes of leadless pacemaker implant in the elderly
Never too old for something new: feasibility and long-term outcomes of leadless pacemaker implant in the elderly Open
Funding Acknowledgements Type of funding sources: None. Elderly patients may be at great risk of complications and present a higher incidence of comorbidities which make challenging PM implant procedure. The use of leadless pacing systems …
View article: ELECTRa Registry Outcome Score (EROS): validation in a single center population
ELECTRa Registry Outcome Score (EROS): validation in a single center population Open
Funding Acknowledgements Type of funding sources: None. Introduction The ELECTRa Registry Outcome Score (EROS) was developed to identify patients at increased transvenous lead extraction (TLE) risk Purpose Aim of the study is to explore th…
View article: The in-ear region as a novel anatomical site for ecg signal detection: validation study on patients affected by atrial tachyarrhythmias
The in-ear region as a novel anatomical site for ecg signal detection: validation study on patients affected by atrial tachyarrhythmias Open
Funding Acknowledgements Type of funding sources: None. Purpose Early detection of cardiac arrhythmias is a major opportunity for mobile health, as portable devices nowadays available can detect multiple-lead electrocardiogram (ECG). The s…
View article: Leadless pacemaker implant in the elderly: a safe and feasible solution
Leadless pacemaker implant in the elderly: a safe and feasible solution Open
The use of leadless pacing systems could overcome peri-and post-procedural complications related to the presence of transvenous leads and the post-operative recovery, being a favorable option in elderly patients. The study aimed to investi…
View article: Early rhythm-control ablation therapy in preventing AF recurrences: insight from the CHARISMA Registry
Early rhythm-control ablation therapy in preventing AF recurrences: insight from the CHARISMA Registry Open
Funding Acknowledgements Type of funding sources: None. Background An early and comprehensive rhythm-control therapy emerges as a need to treat AF in an effective way and to improve the ablation outcomes, in terms of arrhythmia-free surviv…
View article: Leadless pacing in the elderly: never too old for something new
Leadless pacing in the elderly: never too old for something new Open
Rates of cardiac pacemaker implantation rise with age, and, meanwhile, elderly patient may be at great risk of complications, as pneumothorax, lead perforation, or pocket dehiscence. The use of leadless pacemaker could overcome peri- and p…
View article: Transvenous lead extraction: procedural outcomes and in-hospital mortality in octogenarian patients
Transvenous lead extraction: procedural outcomes and in-hospital mortality in octogenarian patients Open
Background Managing elderly patients with infection or malfunction deriving from a cardiac implantable electronic device (CIED) may be challenging. The aim of this study was to evaluate safety and efficacy of mechanical transvenous lead ex…
View article: Off-label combination of leadless pacemakers and subcutaneous defibrillators in bilateral venous occlusion: a new reimplantation strategy after lead extraction
Off-label combination of leadless pacemakers and subcutaneous defibrillators in bilateral venous occlusion: a new reimplantation strategy after lead extraction Open
Background Subcutaneous implantable cardioverter-defibrillator (S-ICD) and leadless pacemakers (LPM) provide an alternative to transvenous implantable devices. Sometimes, after transvenous (TV) lead extraction, patients show a bilateral ve…
View article: Sudden Death Risk in Dilated Cardiomyopathy
Sudden Death Risk in Dilated Cardiomyopathy Open
I risultati derivanti dai recenti trial suggeriscono che la stratificazione del rischio di morte improvvisa nella cardiomiopatia dilatativa non è sufficientemente accurata.Negli ultimi decenni l'indicazione all'impianto in prevenzione prim…
View article: CSD 1791650: Experimental Crystal Structure Determination
CSD 1791650: Experimental Crystal Structure Determination Open
An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely availabl…
View article: ARRHYTHMIAS PACING 2
ARRHYTHMIAS PACING 2 Open
Journal Article ARRHYTHMIAS PACING 2 Get access European Heart Journal Supplements, Volume 21, Issue Supplement_E, May 2019, Pages E116–E118, https://doi.org/10.1093/eurheartj/suz096 Published: 16 May 2019
View article: Outcomes after non-cardiac surgery: mortality, complications, disability, and rehospitalization
Outcomes after non-cardiac surgery: mortality, complications, disability, and rehospitalization Open
In the last 25 years, the number of patients aged ≥75 years undergoing non-cardiac surgery has greatly increased. In elderly patients, frailty is significantly associated with an increased risk of adverse events, functional decline, proced…