Megan S. Lim
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View article: Identification of Microbes from Effective Microbes (EM) Formulations and Spent Mushroom Substrate (SMS) Using Morphological Analysis
Identification of Microbes from Effective Microbes (EM) Formulations and Spent Mushroom Substrate (SMS) Using Morphological Analysis Open
Effective Microbes (EM) formulations and spent mushroom substrate (SMS) are valuable in sustainable agriculture due to their beneficial microbial content. This study aims to culture, isolate, and identify microbial populations in EM and SM…
View article: Supplementary Data 2 from Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells
Supplementary Data 2 from Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells Open
R code of our analysis clock like mutational signatures in Hodgkin lymphoma WGS and WES.
View article: Supplementary Tables from Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells
Supplementary Tables from Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells Open
Supplementary Tables S1-S20
View article: Supplementary Figures from Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells
Supplementary Figures from Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells Open
All supplementary figures S1-S17
View article: Supplementary Data 1 from Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells
Supplementary Data 1 from Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells Open
R code of our analysis for driver mutation discovery in Hodgkin lymphoma WGS and WES.
View article: Transcriptome sequencing of Hodgkin lymphoma Hodgkin and reed-stenberg cells reveals escape from NK cell recognition and an unfolded protein response
Transcriptome sequencing of Hodgkin lymphoma Hodgkin and reed-stenberg cells reveals escape from NK cell recognition and an unfolded protein response Open
Classic Hodgkin lymphoma (cHL) is a B cell malignancy characterized by rare malignant Hodgkin and Reed-Sternberg (HRS) cells within an extensive inflammatory microenvironment. The mutational profile of cHL overlaps with that of related B c…
View article: Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response
Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response Open
The mutational profile of classic Hodgkin lymphoma (cHL) overlaps with that of related B cell lymphomas, including primary mediastinal B cell lymphoma (PMBL), and yet these are different histologically and clinically. To discover the molec…
View article: Multifrequency backscatter classification of seabed sediments using MBES: an integrated approach with ground-truth validation
Multifrequency backscatter classification of seabed sediments using MBES: an integrated approach with ground-truth validation Open
Accurate seabed sediment classification is essential for mapping marine geological features, assessing benthic habitat, and planning coastal infrastructure. This study investigated the utility of multifrequency multibeam echosounder (MBES)…
View article: Palmitoylation by ZDHHC family members regulate B-cell lymphoma growth
Palmitoylation by ZDHHC family members regulate B-cell lymphoma growth Open
The ZDHHC palmitoyl transferase family consists of 24 members, of which several have been linked to the development of cancer. We previously showed that inhibition of ZDHHC11 decreased growth of several B-cell lymphoma subtypes. In this st…
View article: Enhancing seabed sediment classification with multibeam echo-sounding and self-training: a case study from the East Sea of South Korea
Enhancing seabed sediment classification with multibeam echo-sounding and self-training: a case study from the East Sea of South Korea Open
Introduction Accurate classification of seabed sediments is essential for marine spatial planning, resource management, and scientific research. While direct sampling yields precise sediment information, it is costly and spatially limited.…
View article: 394 | RUXOLITINIB TARGETS STAT1‐STAT3 COOPERATIVELY IN LARGE GRANULAR LYMPHOCYTIC LEUKEMIA
394 | RUXOLITINIB TARGETS STAT1‐STAT3 COOPERATIVELY IN LARGE GRANULAR LYMPHOCYTIC LEUKEMIA Open
View article: 120 | DETECTION OF INTRATUMORAL MICROORGANISMS AND THEIR IMPACT ON OUTCOMES IN UNTREATED DIFFUSE LARGE B‐CELL LYMPHOMA
120 | DETECTION OF INTRATUMORAL MICROORGANISMS AND THEIR IMPACT ON OUTCOMES IN UNTREATED DIFFUSE LARGE B‐CELL LYMPHOMA Open
View article: Recurrent schwannomatosis with mosaic SMARCB1 loss: A case report
Recurrent schwannomatosis with mosaic SMARCB1 loss: A case report Open
Schwannomatosis is a non-cancerous disorder causing peripheral nerve sheath tumors (schwannomas), often leading to chronic pain. It is linked to loss of SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily B…
View article: Table S5 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Table S5 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
Supplementary Table S5, FISH analysis to identify copy number variations (CNV) affecting genes of interest within the corresponding genomic loci.
View article: Table S2 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Table S2 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
Supplementary Table S2, Mass spectrometric (MS) identification of GEF-H1-derived peptides in FBXO45 immunoprecipitation. FLAG-tagged FBXO45 expressing B-cell lymphoma cell lines were subjected to immunoprecipitation (IP) with anti-FLAG res…
View article: Table S6 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Table S6 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
Supplementary Table S6, Details of the FISH probes used to identify copy number variations (CNV) affecting FBXO45 and ARHGEF2 in clinical samples.
View article: Table S3 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Table S3 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
Supplementary Table S3, Quantitative whole proteome analysis of pooled sorted GCB-cells from Fbxo45 homozygous knockout mice compared with identically isolated cells from wild-type littermates.
View article: Table S1 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Table S1 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
Supplementary Table S1 shows FBXO45 interactions by immunoprecipitation–tandem mass spectrometry. Normalized Spectral Abundance Factor (NSAF) was calculated as previously published (63). Average NSAFs (n = 3) for the indicated proteins are…
View article: Table S7 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Table S7 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
Supplementary Table S7, Table showing source data and statistics for non-high-throughput experiments such as flow cytometry, quantitative PCR, protein experiments and other molecular and cellular assays.
View article: Supplementary Figures S1-S13 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Supplementary Figures S1-S13 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
Supplementary Data file shows all the supplementary figures, figure legends and supplementary table legends.
View article: Table S4 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Table S4 from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
Supplementary Table S4, Whole genome sequencing of FL, DLBCL and transformed DLBCL reveal loss of FBXO45 as well as copy number gain encompassing ARHGEF2, the gene that encodes GEF H1 protein. Table showing frequency of genomic loss of FBX…
View article: Data from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
Data from The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
The role of ubiquitin-mediated degradation mechanisms in the pathogenesis of diffuse large B-cell lymphoma (BCL) and follicular lymphoma is not completely understood. We show that conditional deletion of the E3 ubiquitin ligase Fbxo45
View article: Evaluation of clinical and immunological responses to recombinant canine interleukin-15 therapy in dogs with cancer: A pilot study
Evaluation of clinical and immunological responses to recombinant canine interleukin-15 therapy in dogs with cancer: A pilot study Open
Interleukin-15 (IL-15) is a pleiotropic cytokine that plays a pivotal role in innate and adaptive immunity. Therefore, it is a promising therapeutic agent for cancer treatment. Despite growing interest in the use of IL-15 as an immunothera…
View article: Characterizing the heterogeneity of Castleman disease and oligocentric subtype: findings from the ACCELERATE registry
Characterizing the heterogeneity of Castleman disease and oligocentric subtype: findings from the ACCELERATE registry Open
Castleman disease (CD) describes a group of rare lymphoproliferative disorders that exhibit a wide range of symptomatology and degree of lymphadenopathy, particularly across the 2 forms of CD with unknown etiology, unicentric CD (UCD), and…
View article: Sound Absorption of the Water Column and Its Calibration for Multibeam Echosounder Backscattered Mapping in the East Sea of Korea
Sound Absorption of the Water Column and Its Calibration for Multibeam Echosounder Backscattered Mapping in the East Sea of Korea Open
Multibeam echosounder (MBES) backscatter data are influenced by underwater sound absorption, which is dependent on environmental parameters such as temperature, salinity, and depth. This study leverages CTD datasets from the Korea Oceanogr…
View article: The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis
The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis Open
The role of ubiquitin-mediated degradation mechanisms in the pathogenesis of diffuse large B-cell lymphoma (BCL) and follicular lymphoma is not completely understood. We show that conditional deletion of the E3 ubiquitin ligase Fbxo45 in g…
View article: Supplementary Data 1 from Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells
Supplementary Data 1 from Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells Open
R code of our analysis for driver mutation discovery in Hodgkin lymphoma WGS and WES.
View article: Supplementary Data 2 from Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells
Supplementary Data 2 from Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells Open
R code of our analysis clock like mutational signatures in Hodgkin lymphoma WGS and WES.
View article: Supplementary Figures from Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells
Supplementary Figures from Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells Open
All supplementary figures S1-S17
View article: Supplementary Data 2 from Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells
Supplementary Data 2 from Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells Open
R code of our analysis clock like mutational signatures in Hodgkin lymphoma WGS and WES.