Hasnah Mohd Sirat
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View article: Characterization and tyrosinase activities of a mixture of β-sitosterol and stigmasterol from Bauhinia rufescens Lam
Characterization and tyrosinase activities of a mixture of β-sitosterol and stigmasterol from Bauhinia rufescens Lam Open
Background: Phytosterols are steroid compounds present in plants that are similar to cholesterol in structure and functions. In this work, stem bark of Bauhinia rufescens was extracted with petroleum ether. Objective: This work aims to det…
View article: Phytochemical and antibacterial screening of leaf extracts from Cassia singueana Del.(Fabaceae)
Phytochemical and antibacterial screening of leaf extracts from Cassia singueana Del.(Fabaceae) Open
No Abstract.
View article: (<i>E</i>)-3-(3-Methylthiophen-2-yl)-1-<i>p</i>-tolylprop-2-en-1-one. Corrigendum
(<i>E</i>)-3-(3-Methylthiophen-2-yl)-1-<i>p</i>-tolylprop-2-en-1-one. Corrigendum Open
In the paper by Naveen et al. [ IUCrData (2017), 2 , x170234], there was an error in the name of one of the authors.
View article: Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae).
Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae). Open
View article: Antityrosinase Inhibitory Activity of Phytochemicals from <i>Alpinia aquatica </i>Roscoe
Antityrosinase Inhibitory Activity of Phytochemicals from <i>Alpinia aquatica </i>Roscoe Open
Background: Genus Alpinia are commonly used as spices and ingredients in traditional medicines. In the present study, we attempted to isolate the phytochemicals from Alpinia aquatica and evaluate their tyrosinase inhibitory activity. Metho…
View article: Essential oils of leaves and pseudo stems Alpinia malaccensis and antimicrobial activities
Essential oils of leaves and pseudo stems Alpinia malaccensis and antimicrobial activities Open
The essential oils from the leaves, pseudo stems, rhizomes and fruits of Alpinia malaccensis, collected from conservation garden, UPM were isolated by hydro distillation. The collected oils were analysed by capillary GC and GC-MS. The leaf…
View article: Ultrasonic Assisted Extraction and Gas Chromatography-Tandem Mass Spectroscopy (GC-MS/MS) Analysis of Extracts from Four Cassia Species
Ultrasonic Assisted Extraction and Gas Chromatography-Tandem Mass Spectroscopy (GC-MS/MS) Analysis of Extracts from Four Cassia Species Open
Ultrasonic assisted extraction (UAE) process increases the rate of extraction, the yield of extracted components and reduces extraction time. The high sensitivity of GC-MS/MS provides reliable identification of phytoconstituents present in…
View article: A new xanthone and a new benzophenone from the roots of Garcinia hombroniana
A new xanthone and a new benzophenone from the roots of Garcinia hombroniana Open
View article: Acetylcholinesterase inhibitory activity of a cyclitol isolated from the leaves of <i>Bauhinia rufescens</i>
Acetylcholinesterase inhibitory activity of a cyclitol isolated from the leaves of <i>Bauhinia rufescens</i> Open
Bauhinia rufescens is a medicinal plant used in the treatment of mycosis, diarrhea and malaria. Leaves of B. rufescens were extracted with organic solvent in a gradient of petroleum ether, ethyl acetate and methanol. Silica gel column puri…
View article: CCDC 1447773: Experimental Crystal Structure Determination
CCDC 1447773: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Síntesis y caracterización estructural de una nueva chalcona conteniendo dos anillos tiofénicos
Síntesis y caracterización estructural de una nueva chalcona conteniendo dos anillos tiofénicos Open
En este trabajo se presenta la síntesis y caracterización estructural de la chalcona (E)-3-(5-bromotiofeno-2-il)-1- (2,5-diclorotiofeno-3-il)-2-propen-1-ona. Este compuesto se sintetizó utilizando el método de condensación de Claisen-Schmi…
View article: Application of Box–Behnken design for ultrasound‐assisted extraction and recycling preparative HPLC for isolation of anthraquinones from <scp><i>Cassia singueana</i></scp>
Application of Box–Behnken design for ultrasound‐assisted extraction and recycling preparative HPLC for isolation of anthraquinones from <span><i>Cassia singueana</i></span> Open
Introduction Cassia singueana Del. (Fabaceae) is a rare medicinal plant used in the traditional medicine preparations to treat various ailments. The root of C. singueana is a rich source of anthraquinones that possess anticancer, antibacte…
View article: Chemical Compositions and Tyrosinase Activity of the Essential Oils of <i>Alpinia aquatica</i>
Chemical Compositions and Tyrosinase Activity of the Essential Oils of <i>Alpinia aquatica</i> Open
The essential oils obtained from the fresh rhizome, leaf, and pseudostem of Alpinia aquatica Roscoe. were hydrodistillated and analyzed using capillary gas chromatography (GC) and gas chromatography-mass spectroscopy (GC-MS). β-Pinene (11.…
View article: Chemical Composition, Antioxidant, Antimicrobial, and α-Glucosidase Activities of Essential Oils of <i>Hornstedtia scyphifera</i> (Zingiberaceae)
Chemical Composition, Antioxidant, Antimicrobial, and α-Glucosidase Activities of Essential Oils of <i>Hornstedtia scyphifera</i> (Zingiberaceae) Open
The essential oil compositions of the rhizomes, flowers, leaves, and pseudostems of Hornstedtia scyphifera (J. Koenig) Steud were studied for the first time. A total of forty three constituents were identified from the rhizome, flower, lea…
View article: Bioassay-Guided Isolation of Antioxidants and alpha-Glucosidase Inhibitors from the Root of Cassia sieberiana DC (Fabaceae)
Bioassay-Guided Isolation of Antioxidants and alpha-Glucosidase Inhibitors from the Root of Cassia sieberiana DC (Fabaceae) Open
Bioassay-guided isolation was used to investigate the antioxidants and alpha-glucosidase inhibitors from extract of root of Cassia sieberiana. The ethyl acetate fraction demonstrated strong free radical scavenging (DPPH and ABTS(+)) and po…
View article: A New Stilbene from the Root of <i>Cassia sieberiana</i> D.C. (Fabaceae)
A New Stilbene from the Root of <i>Cassia sieberiana</i> D.C. (Fabaceae) Open
A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3–5), six anthraquinones (6–11), two triterpenes (12–13), and phytosterol (14). Their stru…
View article: Synthesis and study of anti-HIV-1 RT activity of 5-benzoyl-4-methyl-1,3,4,5-tetrahydro- 2H -1,5-benzodiazepin-2-one derivatives
Synthesis and study of anti-HIV-1 RT activity of 5-benzoyl-4-methyl-1,3,4,5-tetrahydro- 2H -1,5-benzodiazepin-2-one derivatives Open
View article: (<i>E</i>)-3-(3-Methylthiophen-2-yl)-1-<i>p</i>-tolylprop-2-en-1-one
(<i>E</i>)-3-(3-Methylthiophen-2-yl)-1-<i>p</i>-tolylprop-2-en-1-one Open
In the title compound, C 15 H 14 OS, the dihedral angle between the thiophene and benzene rings is 31.34 (13)°. The thiophene S atom and enone C=O group are approximately in an anti orientation. In the crystal, molecules are linked via pai…
View article: CCDC 1569745: Experimental Crystal Structure Determination
CCDC 1569745: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Chemical Composition, Antibacterial and α-Glucosidase Inhibitory Activities of the Essential Oils of <i>Neolitsea coccinea</i> (Lauraceae)
Chemical Composition, Antibacterial and α-Glucosidase Inhibitory Activities of the Essential Oils of <i>Neolitsea coccinea</i> (Lauraceae) Open
The chemical composition, antibacterial and α-glucosidase inhibitory activities of the essential oils obtained from hydrodistillation of the fresh stem and leaf of Neolitsea coccinea B. C. Stone are reported for the first time. GC and GC-M…
View article: TWO NEW PRENYLATED CHALCONES FROM THE LEAVES OF ARTOCARPUS LOWII KING
TWO NEW PRENYLATED CHALCONES FROM THE LEAVES OF ARTOCARPUS LOWII KING Open
Two minor prenylated chalcones were isolated for the first time from the leaves of Artocarpus lowii King. These prenylated chalcones were identified as 2-hydroxyparatocarpin C (1) and 2¢,3,4¢,4-tetrahydroxy-3¢-prenylchalcone (2). The struc…
View article: Flavonoids from the Bark of <i>Artocarpus integer</i> var. <i>silvestris</i> and their Anti-inflammatory Properties
Flavonoids from the Bark of <i>Artocarpus integer</i> var. <i>silvestris</i> and their Anti-inflammatory Properties Open
A new pyranoflavone, methoxycyclocommunol (1) together with four known flavonoids, artonin F (2), heteroflavanone A (3), cudraflavone C (4) and cyclocommunol (5) were isolated from the bark of Artocarpus integer var. silvestris Corner. The…
View article: CHOLINESTERASE INHIBITORS FROM HEARTWOOD OF ARTOCARPUS FULVICORTEX F. M. JARRET (MORACEAE)
CHOLINESTERASE INHIBITORS FROM HEARTWOOD OF ARTOCARPUS FULVICORTEX F. M. JARRET (MORACEAE) Open
Cholinesterase inhibition activities were screened on crude extracts and isolated compounds of the heartwood of Artocarpus fulvicortex. Phytochemical studies on the heartwood of A. fulvicortex have resulted in the isolation of one flavonoi…
View article: DETERMINATION OF THE ABSOLUTE CONFIGURATION OF NEW PIPERIDIN-4-ONE DERIVATIVE FROM Pellacalyx saccardianus BY NOESY SPECTROSCOPY
DETERMINATION OF THE ABSOLUTE CONFIGURATION OF NEW PIPERIDIN-4-ONE DERIVATIVE FROM Pellacalyx saccardianus BY NOESY SPECTROSCOPY Open
A new alkaloid, pellacalyxin was isolated from the leaves of Pellacalyx saccardianus of Rhizophoraceae family. Pellacalyxin was analyzed using nuclear Overhauser spectroscopy (NOESY) nuclear magnetic resonance (NMR) technique to determine …
View article: Antioxidant and Anti-inflammatory Activities of Essential Oil and Extracts of <i>Piper miniatum</i>
Antioxidant and Anti-inflammatory Activities of Essential Oil and Extracts of <i>Piper miniatum</i> Open
The chemical composition of the essential oil and antioxidant and anti-inflammatory activities of the extracts from Piper miniatum were determined. GC and GC–MS analysis of the essential oil resulted in the identification of 64 components,…
View article: SYNTHESIS AND CHARACTERIZATION OF HETEROCYCLIC CHALCONES CONTAINING HALOGENATED THIOPHENES
SYNTHESIS AND CHARACTERIZATION OF HETEROCYCLIC CHALCONES CONTAINING HALOGENATED THIOPHENES Open
Heterocyclic chalcones containing halogenated thiophenes were synthesized. The first step was to synthesize 3-acetyl-2,5-dichlorothiophene and 2-acetyl-5-chlorothiophene as heterocyclic ketones by using Friedel-Crafts acylation. The ketone…
View article: INHIBITORY EFFECT OF ARTOCARPUS LOWII KING COMPOUNDS ON COX-2 AND 15-LO ACTIVITIES
INHIBITORY EFFECT OF ARTOCARPUS LOWII KING COMPOUNDS ON COX-2 AND 15-LO ACTIVITIES Open
Artocarpus lowii King is a rare species of plant in Moraceae family. In this study, the anti-inflammatory activity of cycloheterophyllin, isobavachalcone, 4-hydroxylonchocarpin and 2’,4’-dihydroxy-4-methoxy-3’-prenyldihydroxychalcone isola…
View article: ANTIOXIDANT ACTIVITY OF PIPER CANINUM AND CYCLOOXYGENASE-2 INHIBITION BY METHOXYLATED FLAVONES
ANTIOXIDANT ACTIVITY OF PIPER CANINUM AND CYCLOOXYGENASE-2 INHIBITION BY METHOXYLATED FLAVONES Open
Background: The crude extracts and pure compounds isolated from Piper caninum was studied for their bioactivities.
Material and method: The present study was carried out with the following aims: (1) to quantify the total phenolic content…