Michael E. Jessen
YOU?
Author Swipe
View article: Development and Validation of a Hybrid Machine Learning Model to Predict Lung Transplant Outcomes
Development and Validation of a Hybrid Machine Learning Model to Predict Lung Transplant Outcomes Open
Importance Long-term survival after a lung transplant remains highly variable, and existing risk stratification tools have limited accuracy, clinical utility, and interpretability. Objective To develop, validate, and assess the clinical ut…
View article: On the influence of language similarity in non-target speaker verification trials
On the influence of language similarity in non-target speaker verification trials Open
In this paper, we investigate the influence of language similarity in cross-lingual non-target speaker verification trials using a state-of-the-art speaker verification system, ECAPA-TDNN, trained on multilingual and monolingual variants o…
View article: Deteriorated biomechanical properties of human hypertrophied septum in response to cardiomyocyte enlargement, overexpressed collagen, and disarrayed microstructures
Deteriorated biomechanical properties of human hypertrophied septum in response to cardiomyocyte enlargement, overexpressed collagen, and disarrayed microstructures Open
Hypertrophic cardiomyopathy (HCM) is often caused by genetic mutations, resulting in abnormal thickening of ventricular muscle, particularly the septum, and causing left ventricular outflow tract (LVOT) obstruction and inferior cardiac per…
View article: Access Options for Transcatheter Aortic Valve Replacement
Access Options for Transcatheter Aortic Valve Replacement Open
Transcatheter aortic valve replacement (TAVR) was introduced in 2002 and has become integral in the management of aortic stenosis. As an alternative to surgical aortic valve replacement, it relies heavily on safe access to the aortic annul…
View article: Effects of RBT‐1 on the Occurrence of Postoperative Complications in Patients Undergoing Cardiac Surgery
Effects of RBT‐1 on the Occurrence of Postoperative Complications in Patients Undergoing Cardiac Surgery Open
Objectives Approximately two‐thirds of patients undergoing cardiac surgery experience postoperative complications, which may lead to significant clinical consequences. RBT‐1, an investigational drug with anti‐inflammatory and antioxidant p…
View article: Afterload-induced Decreases in Fatty Acid Oxidation Develop Independently of Increased Glucose Utilization
Afterload-induced Decreases in Fatty Acid Oxidation Develop Independently of Increased Glucose Utilization Open
Background Metabolic substrate utilization in HFpEF (heart failure with preserved ejection fraction), the leading cause of heart failure worldwide, is pivotal to syndrome pathogenesis and yet remains ill defined. Under resting conditions, …
View article: RBT-1 reduces blood product utilization in patients undergoing nonemergency coronary artery bypass grafting and/or valve surgery
RBT-1 reduces blood product utilization in patients undergoing nonemergency coronary artery bypass grafting and/or valve surgery Open
Central MessageIn this Phase 2 study, patients undergoing CABG and/or valve surgery treated with RBT-1 required less blood transfusion/blood product use compared with placebo.See Commentary on page XXX. In this Phase 2 study, patients unde…
View article: Ex vivo lung perfusion in donation after circulatory death: A post hoc analysis of the Normothermic Ex Vivo Lung Perfusion as an Assessment of Extended/Marginal Donors Lungs trial
Ex vivo lung perfusion in donation after circulatory death: A post hoc analysis of the Normothermic Ex Vivo Lung Perfusion as an Assessment of Extended/Marginal Donors Lungs trial Open
Although DCD EVLP allografts might not be appropriate to transplant in every candidate recipient, the expansion of their use might afford recipients stagnant on the waitlist a viable therapy.
View article: Effects of RBT-1 on preconditioning response biomarkers in patients undergoing coronary artery bypass graft or heart valve surgery: a multicentre, double-blind, randomised, placebo-controlled phase 2 trial
Effects of RBT-1 on preconditioning response biomarkers in patients undergoing coronary artery bypass graft or heart valve surgery: a multicentre, double-blind, randomised, placebo-controlled phase 2 trial Open
Renibus Therapeutics, Inc.
View article: Left bundle branch pacing after His bundle lead dysfunction due to physical activity in a pediatric patient
Left bundle branch pacing after His bundle lead dysfunction due to physical activity in a pediatric patient Open
Key Teaching Points•His bundle pacing may not be suitable in all pediatric patients, as lead micro-dislodgement may occur in children who engage in physically vigorous activities.•Safe extraction of His bundle pacing leads is achievable; a…
View article: Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)
Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC) Open
Selective vascular access to the brain is desirable in metabolic tracer, pharmacological and other studies aimed to characterize neural properties in isolation from somatic influences from chest, abdomen or limbs. However, current methods …
View article: Distributional and Acoustic Characteristics of Filler Particles in German with Consideration of Forensic-Phonetic Aspects
Distributional and Acoustic Characteristics of Filler Particles in German with Consideration of Forensic-Phonetic Aspects Open
In this study, we investigate the use of the filler particles (FPs) uh, um, hm, as well as glottal FPs and tongue clicks of 100 male native German speakers in a corpus of spontaneous speech. For this purpose, the frequency distribution, FP…
View article: Cardioscopy-Assisted Removal of Intracavitary Left Ventricular Papillary Fibroelastoma
Cardioscopy-Assisted Removal of Intracavitary Left Ventricular Papillary Fibroelastoma Open
A 72-year-old woman was incidentally discovered to have a left ventricular mass during work-up for coronary artery bypass grafting surgery. Cardiac MR revealed a 2-cm left ventricular intracavitary mass. During concomitant coronary artery …
View article: Consensus on validation of forensic voice comparison
Consensus on validation of forensic voice comparison Open
Since the 1960s, there have been calls for forensic voice comparison to be empirically validated under casework conditions. Since around 2000, there have been an increasing number of researchers and practitioners who conduct forensic-voice…
View article: Preemptive Alcohol Septal Ablation Prior to Valve-in-Valve Transcatheter Mitral Valve Replacement With Bioprosthetic Balloon Fracture
Preemptive Alcohol Septal Ablation Prior to Valve-in-Valve Transcatheter Mitral Valve Replacement With Bioprosthetic Balloon Fracture Open
A 78-year-old woman with bioprosthetic mitral valve degeneration at high risk for reoperation was referred for transcatheter mitral valve replacement. We describe the use of a preemptive alcohol septal ablation pre-procedurally to minimize…
View article: State of the Art: Evaluation and Management of Patients with Cardiac Papillary Fibroelastoma
State of the Art: Evaluation and Management of Patients with Cardiac Papillary Fibroelastoma Open
Objective: To review the current literature on the state of the art of evaluation and management of cardiac papillary fibroelastoma (PFE). Methods: A literature review was performed on the topic of evaluation and management of PFE. PubWeb,…
View article: Expansion of TAVR into Low-Risk Patients and Who to Consider for SAVR
Expansion of TAVR into Low-Risk Patients and Who to Consider for SAVR Open
Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of severe aortic stenosis (AS) over the last decade. The results of the Placement of Aortic Transcatheter Valves (PARTNER) 3 and Evolut Low Risk trials demonstr…