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View article: Pattern of lymph node recurrence in upper tract urothelial carcinoma after lymph node dissection: Recommendations for optimizing the area of lymph node dissection
Pattern of lymph node recurrence in upper tract urothelial carcinoma after lymph node dissection: Recommendations for optimizing the area of lymph node dissection Open
Purpose The implementation of standardized lymph node dissection (LND) remains limited in real-world practice. We aimed to analyze the prognosis and recurrence patterns of UTUC patients who underwent LND in real-world practice, with the go…
View article: Translation and psychometric validation of the Escala de Impactos da Mucosite Oral em Pacientes Oncológicos (EIMOPO) in Chinese patients with cancer
Translation and psychometric validation of the Escala de Impactos da Mucosite Oral em Pacientes Oncológicos (EIMOPO) in Chinese patients with cancer Open
View article: A Multimodal Machine Learning Framework for Box Office Prediction Using CNN-Based Trailer Analysis and Random Forest Models
A Multimodal Machine Learning Framework for Box Office Prediction Using CNN-Based Trailer Analysis and Random Forest Models Open
This study presents a comprehensive multimodal machine learning framework for box office prediction in the Chinese film market. We develop an integrated approach combining multiple computational techniques: time series analysis for market …
View article: Data-driven subtypes of polycystic ovary syndrome and their association with clinical outcomes
Data-driven subtypes of polycystic ovary syndrome and their association with clinical outcomes Open
Polycystic ovary syndrome (PCOS) is a common and heterogeneous endocrine disorder that affects 11%-13% of women worldwide, with profound implications for fertility and long-term metabolic health. Here we identify four reproducible subtypes…
View article: MiR-125b-5p targets Bak1 to regulate HCT-8 cell apoptosis in response to Cryptosporidium parvum infection via mitochondrial pathway
MiR-125b-5p targets Bak1 to regulate HCT-8 cell apoptosis in response to Cryptosporidium parvum infection via mitochondrial pathway Open
View article: Edamame Growth Stages in Miami-Dade County
Edamame Growth Stages in Miami-Dade County Open
This EDIS publication provides an overview of the growth stages of edamame (Glycine max (L.) Merr.), a promising new crop introduced in Miami-Dade County. This information covers the physiological changes that occur during each development…
View article: Secretome and Transcriptome Analyses Reveal New Potential Virulence Factors during <i>Cryptosporidium parvum</i> Invasion
Secretome and Transcriptome Analyses Reveal New Potential Virulence Factors during <i>Cryptosporidium parvum</i> Invasion Open
Cryptosporidium parvum is a major cause of life-threatening diarrheal disease in young children and immunocompromised individuals. During the initial infection, C. parvum secretes a large number of virulence proteins that hel…
View article: Comparison of the safety and efficacy of moderately hypofractionated and conventionally fractionated radiotherapy for localized prostate cancer: evidence from 9074 men in 13 randomized clinical trials
Comparison of the safety and efficacy of moderately hypofractionated and conventionally fractionated radiotherapy for localized prostate cancer: evidence from 9074 men in 13 randomized clinical trials Open
View article: Overexpression of the Lipid Transfer Protein Gene SpLTP1 from Desert Pioneer Plant Stipagrostis pennata Enhances the Drought Tolerance in Arabidopsis
Overexpression of the Lipid Transfer Protein Gene SpLTP1 from Desert Pioneer Plant Stipagrostis pennata Enhances the Drought Tolerance in Arabidopsis Open
Lipid transfer proteins (LTPs) play crucial regulatory roles in plant growth, development, and abiotic stress responses. Stipagrostis pennata is a species of grass widely distributed in arid and semi-arid regions, particularly adapted to d…
View article: Add-on ketogenic diet versus antiseizure medications alone in children with developmental and epileptic encephalopathies: a prospective comparative cohort study
Add-on ketogenic diet versus antiseizure medications alone in children with developmental and epileptic encephalopathies: a prospective comparative cohort study Open
Objective To compare the effectiveness and safety of ketogenic diet (KD) versus antiseizure medications (ASMs) adjustment in developmental and epileptic encephalopathy (DEE). Methods In this prospective, single-center cohort study, 268 par…
View article: Effect of magnetic auricular acupuncture on pain during ophthalmic examination of the newborn: a multicenter, triple-blinded, randomized controlled study
Effect of magnetic auricular acupuncture on pain during ophthalmic examination of the newborn: a multicenter, triple-blinded, randomized controlled study Open
MAA may offer an alternative or adjunct to current non-pharmacologic and pharmacologic interventions to alleviate neonatal pain. Future studies should assess combinations of pain interventions and long term outcomes.
View article: A sequential dual-site repetitive transcranial magnetic stimulation for major depressive disorder: A randomized clinical trial
A sequential dual-site repetitive transcranial magnetic stimulation for major depressive disorder: A randomized clinical trial Open
Repetitive transcranial magnetic stimulation (rTMS) is approved for major depressive disorder (MDD), but it is limited by variable efficacy. Here, we examine antidepressant effects of our sequential dorsolateral prefrontal cortex (dlPFC)-d…
View article: Unveiling the ‘Eating Poison’ of Polygala tenuifolia xylem: Mood changes and myocardial injury
Unveiling the ‘Eating Poison’ of Polygala tenuifolia xylem: Mood changes and myocardial injury Open
View article: Supplementary Material
Supplementary Material Open
This dataset comprises experimental measurements and model predictions for analyzing the Mode I interlaminar fracture toughness (GIC) of additively manufactured continuous glass fiber-reinforced polyetheretherketone (CGF/PEEK) composites. …
View article: Radiological frontiers in understanding paraspinal muscle pathophysiology in chronic low back pain
Radiological frontiers in understanding paraspinal muscle pathophysiology in chronic low back pain Open
Background Paraspinal muscles have a profound role in maintaining spinal stability and are often implicated in spinal degenerative conditions as well as chronic low back pain (CLBP). Alterations in these muscles have significant clinical i…
View article: Effect of Nano-Selenium on Intestinal Oxidative Stress Induced by H2O2 in Mice
Effect of Nano-Selenium on Intestinal Oxidative Stress Induced by H2O2 in Mice Open
Selenium is an important trace element with certain antioxidant effects. Nano-selenium, as a novel selenium source, has the advantages of strong biological activity, high absorption efficiency, and low toxicity. The aim of the present stud…
View article: Menstrual blood-derived endometrial stem cells ameliorate neuroinflammation and apoptosis through JAK2/STAT3 signaling pathway in NPC1 mutant cell and mice
Menstrual blood-derived endometrial stem cells ameliorate neuroinflammation and apoptosis through JAK2/STAT3 signaling pathway in NPC1 mutant cell and mice Open
Our study demonstrate that MenSCs ameliorate neuroinflammation and apoptosis in NPC1 mutant cell and mice through JAK2/STAT3 signaling pathway.
View article: Serplulimab combined with gemcitabine, nab-paclitaxel, and stereotactic body radiotherapy as first-line treatment for metastatic pancreatic adenocarcinoma: a multicentre, single-arm, phase II trial
Serplulimab combined with gemcitabine, nab-paclitaxel, and stereotactic body radiotherapy as first-line treatment for metastatic pancreatic adenocarcinoma: a multicentre, single-arm, phase II trial Open
Metastatic pancreatic ductal adenocarcinoma (mPDAC) is a highly aggressive cancer associated with extremely poor outcomes. We postulated that a combination of immunotherapy, chemotherapy, and stereotactic body radiation therapy (ICSBR) cou…
View article: High-quality chromosome-level genome assembly of Davidia involucrata reveals evolutionary insights into tannin biosynthesis and bract development
High-quality chromosome-level genome assembly of Davidia involucrata reveals evolutionary insights into tannin biosynthesis and bract development Open
View article: [Total 3D laparoscopic ileal ureters replacement for bilateral ureters combined with bladder augmentation in the management of post-radiotherapy bilateral ureteral strictures and contracted bladder].
[Total 3D laparoscopic ileal ureters replacement for bilateral ureters combined with bladder augmentation in the management of post-radiotherapy bilateral ureteral strictures and contracted bladder]. Open
Membrane anatomy-based dissection facilitates safe mobilization of fibrotic ureters with minimal bleeding and collateral damage. Total intracorporeal 3D laparoscopic ileal ureters replacement for bilateral ureters combined with bladder aug…
View article: CAR Cell-Derived Exosomes in Cancer Therapy: Biogenesis, Engineering Strategies and Antitumor Mechanisms
CAR Cell-Derived Exosomes in Cancer Therapy: Biogenesis, Engineering Strategies and Antitumor Mechanisms Open
Chimeric antigen receptor (CAR) cell therapy, encompassing CAR T, CAR NK, and CAR macrophage cells, demonstrates high efficacy in tumor treatment, conferring durable and effective responses, notably in hematologic malignancies. However, ch…
View article: Role and mechanism of Integrin α5β1 in bone formation and disease
Role and mechanism of Integrin α5β1 in bone formation and disease Open
Integrin α5β1 is a key signaling protein between cells and the extracellular matrix. It plays crucial roles in biological processes such as cell adhesion, migration, and differentiation. Recent studies have shown that integrin α5β1 is sign…
View article: Can working in agriculture have a favorable effect on depressive symptoms? Life satisfaction as a mediator
Can working in agriculture have a favorable effect on depressive symptoms? Life satisfaction as a mediator Open
Purpose Several studies have explored the relationship between various aspects of work and the onset of depressive symptoms. However, there is a lack of research focusing on the association between job types and depressive symptoms. This s…
View article: Cardiometabolic index is a novel predictor for osteoporosis in type 2 diabetes mellitus patients with MAFLD: a cross-sectional study
Cardiometabolic index is a novel predictor for osteoporosis in type 2 diabetes mellitus patients with MAFLD: a cross-sectional study Open
CMI shows a significant negative correlation with BMD in T2DM patients with MAFLD. It is an independent risk factor for OP in this patient population, offering a new direction for the prevention and screening of OP in individuals with T2DM…
View article: Pre- and post-diagnosis dietary total antioxidant capacity and overall survival in patients with ovarian cancer: a prospective cohort study
Pre- and post-diagnosis dietary total antioxidant capacity and overall survival in patients with ovarian cancer: a prospective cohort study Open
Increased pre- and post-diagnosis DTAC intake, and maintaining moderate or high DTAC intake after diagnosis, may be associated with enhanced OS in patients with OC.
View article: Retroperitoneal invasive fibromatosis after laparoscopic radical resection of colon cancer: a case report and literature review
Retroperitoneal invasive fibromatosis after laparoscopic radical resection of colon cancer: a case report and literature review Open
Invasive fibromatosis is a rare, locally invasive, benign fibrous tumor that mainly occurs in the anterior abdominal wall and limbs, with a lower incidence in the retroperitoneum. This article reports a case of retroperitoneal invasive fib…
View article: Overexpression of the β-Glucosidase Gene SpBGLU25 from the Desert Pioneer Plant Stipagrostis pennata Enhances the Drought Tolerance in Arabidopsis
Overexpression of the β-Glucosidase Gene SpBGLU25 from the Desert Pioneer Plant Stipagrostis pennata Enhances the Drought Tolerance in Arabidopsis Open
This research centers on the sand-fixing plant known as Stipagrostis pennata, from which the β-glucosidase gene SpBGLU25 was successfully cloned using the molecular cloning method. SpBGLU25 encodes a hydrophilic and stable protein made up …
View article: Associations between dietary macronutrient quality and odds of hyperlipidemia: findings from the NEC-Biobank cohort
Associations between dietary macronutrient quality and odds of hyperlipidemia: findings from the NEC-Biobank cohort Open
View article: Identification and Expression Pattern Analysis of AsSWEET Gene Family in Achnatherum splendens
Identification and Expression Pattern Analysis of AsSWEET Gene Family in Achnatherum splendens Open
Sugars Will Eventually Be Exported Transporters (SWEETs) are involved in plant growth and development, particularly in resistance to adverse environments. Achnatherum splendens (Trin.) Nevski exhibits rhizosheath formation and demonstrates…
View article: <scp>CD81</scp> Aggravates Ovarian Cancer Progression via p‐Cresyl Sulfate‐Mediated Mitophagy in Tim4<sup>+</sup> Tumour‐Associated Macrophages
<span>CD81</span> Aggravates Ovarian Cancer Progression via p‐Cresyl Sulfate‐Mediated Mitophagy in Tim4<sup>+</sup> Tumour‐Associated Macrophages Open
Ovarian cancer (OC) is characterised by widespread peritoneal metastasis. Tetraspanin CD81 is predominantly located at the cellular membrane and exhibits inconsistent roles in tumour progression. However, its precise function in OC remains…