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View article: Patient Portal Engagement in Oncology: Results From the NU IMPACT Study in a Large Health Care System
Patient Portal Engagement in Oncology: Results From the NU IMPACT Study in a Large Health Care System Open
PURPOSE Electronic patient portals can promote patient-centered care, but determinants of engagement remain underexplored in oncology. This study examines sociodemographic and clinical factors associated with engagement with four portal fe…
View article: Web-Based Cancer Symptom Self-Management System
Web-Based Cancer Symptom Self-Management System Open
Importance Patients with cancer and cancer survivors frequently experience symptoms that increase the need for health care services and impair quality of life. Effective symptom management is critical for comprehensive patient-centered can…
View article: Development of a method for qualitative data integration to advance implementation science within research consortia
Development of a method for qualitative data integration to advance implementation science within research consortia Open
Limited guidance exists on how to support qualitative data integration, data exchange, and sharing across multiple studies. This paper describes a systematic method for employing an implementation determinant framework-guided approach to f…
View article: Implementation of patient-reported outcome dashboards within the electronic health record to support shared decision-making in serious chronic illness
Implementation of patient-reported outcome dashboards within the electronic health record to support shared decision-making in serious chronic illness Open
Background Attending to patient-reported outcomes (PROs) using data visualisation dashboards could enhance shared decision-making (SDM) and care delivery for serious chronic illnesses. However, few studies have evaluated real-world strateg…
View article: Personality Feedback With Tailored Self‐Care Recommendations Improves Self‐Efficacy for Cancer Management: A Randomized Controlled Trial
Personality Feedback With Tailored Self‐Care Recommendations Improves Self‐Efficacy for Cancer Management: A Randomized Controlled Trial Open
Objective To test whether a personality feedback intervention improves three domains of cancer self‐management: self‐awareness, self‐efficacy, and positive affect. Methods From 11/2020‐02/2021, 372 adults diagnosed with cancer participated…
View article: The Impact of Next-Generation Sequencing Workflows on Outcomes in Advanced Lung Cancer: A Retrospective Analysis at One Academic Health System
The Impact of Next-Generation Sequencing Workflows on Outcomes in Advanced Lung Cancer: A Retrospective Analysis at One Academic Health System Open
Purpose: Broad-based molecular testing with next-generation sequencing (NGS) is now the standard of care in advanced non-small cell lung cancer (NSCLC). Two approaches to molecular testing are (1) reflexive testing at pathologic NSCLC conf…
View article: A phase II study of FOLFOX combined with nab-paclitaxel in the treatment of metastatic or advanced unresectable gastric, gastroesophageal junction adenocarcinoma: a Big Ten Cancer Research Consortium trial
A phase II study of FOLFOX combined with nab-paclitaxel in the treatment of metastatic or advanced unresectable gastric, gastroesophageal junction adenocarcinoma: a Big Ten Cancer Research Consortium trial Open
Background Doublet platinum or taxane-based therapies are the current standard backbone of treatment for advanced gastric/gastroesophageal junction (GEJ) adenocarcinoma. Previously used anthracycline-based triplet regimens are no longer us…
View article: Exploring the Relationship Among Financial Hardship, Anxiety, and Depression in Patients With Cancer: A Longitudinal Study
Exploring the Relationship Among Financial Hardship, Anxiety, and Depression in Patients With Cancer: A Longitudinal Study Open
PURPOSE Financial hardship (FH) is a complex issue in cancer care, affecting material conditions, well-being, and coping behaviors. This study aimed to longitudinally examine FH, anxiety, depressive symptoms, and their associations while i…
View article: Shared decision-making and disease management in advanced cancer and chronic kidney disease using patient-reported outcome dashboards
Shared decision-making and disease management in advanced cancer and chronic kidney disease using patient-reported outcome dashboards Open
Objectives To assess the use of a co-designed patient-reported outcome (PRO) clinical dashboard and estimate its impact on shared decision-making (SDM) and symptomatology in adults with advanced cancer or chronic kidney disease (CKD). Mate…
View article: Implementation of a Co-Design Strategy to Develop a Dashboard to Support Shared Decision Making in Advanced Cancer and Chronic Kidney Disease
Implementation of a Co-Design Strategy to Develop a Dashboard to Support Shared Decision Making in Advanced Cancer and Chronic Kidney Disease Open
Background: Shared decision making (SDM) is the process by which patients and clinicians exchange information and preferences to come to joint healthcare decisions. Clinical dashboards can support SDM by collecting, distilling, and present…
View article: Development of an electronic health record-integrated patient-reported outcome-based shared decision-making dashboard in oncology
Development of an electronic health record-integrated patient-reported outcome-based shared decision-making dashboard in oncology Open
Objectives Patient-reported outcomes (PROs) describe a patient’s unique experiences with disease or treatment, yet effective use of this information during clinical encounters remains challenging. This project sought to build a PRO based d…
View article: Bridging clinical informatics and implementation science to improve cancer symptom management in ambulatory oncology practices: experiences from the IMPACT consortium
Bridging clinical informatics and implementation science to improve cancer symptom management in ambulatory oncology practices: experiences from the IMPACT consortium Open
Objectives To report lessons from integrating the methods and perspectives of clinical informatics (CI) and implementation science (IS) in the context of Improving the Management of symPtoms during and following Cancer Treatment (IMPACT) C…
View article: Scalable Telehealth Cancer Care: integrated healthy lifestyle program to live well after cancer treatment
Scalable Telehealth Cancer Care: integrated healthy lifestyle program to live well after cancer treatment Open
Northwestern University’s Center for Scalable Telehealth Cancer Care (STELLAR) is 1 of 4 Cancer Moonshot Telehealth Research Centers of Excellence programs funded by the National Cancer Institute to establish an evidence base for telehealt…
View article: Oncologic drug repository programs in the United States: a review and comparison
Oncologic drug repository programs in the United States: a review and comparison Open
As cancer affects 40% of all Americans during their lifetime, the financial burden of cancer care represents a significant contribution towards the overall cost of health care in the United States. Cancer drug repository programs offer a u…
View article: Implementing a Patient-Reported Outcome Dashboard in Oncology Telemedicine Encounters: Clinician and Patient Adoption and Acceptability
Implementing a Patient-Reported Outcome Dashboard in Oncology Telemedicine Encounters: Clinician and Patient Adoption and Acceptability Open
PURPOSE Telemedicine provides numerous benefits to patients, yet effective communication and symptom assessment remain a concern. The recent uptake of telemedicine provided an opportunity to use a newly developed dashboard with patient-rep…
View article: Patient-Reported Financial Burden of Treatment for Colon or Rectal Cancer
Patient-Reported Financial Burden of Treatment for Colon or Rectal Cancer Open
Importance The longitudinal experience of patients is critical to the development of interventions to identify and reduce financial hardship. Objective To evaluate financial hardship over 12 months in patients with newly diagnosed colorect…
View article: Systematic symptom management in the IMPACT Consortium: rationale and design for 3 effectiveness-implementation trials
Systematic symptom management in the IMPACT Consortium: rationale and design for 3 effectiveness-implementation trials Open
Cancer and its treatment produce deleterious symptoms across the phases of care. Poorly controlled symptoms negatively affect quality of life and result in increased health-care needs and hospitalization. The Improving the Management of sy…
View article: Adverse COVID-19 experiences and health-related quality of life in cancer survivors: indirect effects of COVID-19-related depression and financial burden
Adverse COVID-19 experiences and health-related quality of life in cancer survivors: indirect effects of COVID-19-related depression and financial burden Open
Background Cancer survivors are at greater risk for poor health outcomes due to COVID-19. However, the pandemic's impact on patients’ health-related quality of life (HRQoL) is not well known. This study hypothesized that cancer survivors' …
View article: Perspectives of private payers on multicancer early-detection tests: informing research, implementation, and policy
Perspectives of private payers on multicancer early-detection tests: informing research, implementation, and policy Open
Emerging blood-based multicancer early-detection (MCED) tests may redefine cancer screening, reduce mortality, and address health disparities if their benefit is demonstrated. U.S. payers’ coverage policies will impact MCED test adoption a…
View article: Medical Oncologists' Knowledge and Perspectives on the Use of Biosimilars in the United States
Medical Oncologists' Knowledge and Perspectives on the Use of Biosimilars in the United States Open
PURPOSE: Despite increasing availability of biosimilar cancer treatments, little is known about oncologists' knowledge and concerns regarding biosimilar use in the United States. We surveyed medical oncologists to examine their knowledge, …
View article: A Qualitative Study of Medical Oncologists’ Knowledge and Views of Biosimilars in the United States
A Qualitative Study of Medical Oncologists’ Knowledge and Views of Biosimilars in the United States Open
Background: As the cost of cancer care continues to rise, biosimilars provide an important cost-saving treatment option. Thus, understanding barriers to biosimilar uptake, including perceptions of biosimilars among oncologists, is critical…
View article: Resource and Reimbursement Barriers to Comprehensive Cancer Care Delivery: An Analysis of Association of Community Cancer Centers Survey Data
Resource and Reimbursement Barriers to Comprehensive Cancer Care Delivery: An Analysis of Association of Community Cancer Centers Survey Data Open
PURPOSE: Comprehensive cancer care (CCC) delivery is recommended in guidelines and considered essential for high-quality cancer management. Barriers, such as insufficient reimbursement, prevent consistent access to and delivery of CCC. Ass…