Marie‐Laure Tanguy
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View article: Evaluation of a nurse-led program for the prevention of complications of long-term glucocorticoids (COCORTICO): study protocol for a randomized trial
Evaluation of a nurse-led program for the prevention of complications of long-term glucocorticoids (COCORTICO): study protocol for a randomized trial Open
View article: Assessing Rubella Immunity: Seroprevalence among Pregnant Women in Brazzaville, Congo
Assessing Rubella Immunity: Seroprevalence among Pregnant Women in Brazzaville, Congo Open
Background: Rubella is a major public health problem because of its teratogenic effects, especially in early pregnancy. Understanding the serological profile of pregnant women is crucial to preventing congenital rubella syndrome. This stud…
View article: Data from Recurrent Mutations of <i>MYD88</i> and <i>TBL1XR1</i> in Primary Central Nervous System Lymphomas
Data from Recurrent Mutations of <i>MYD88</i> and <i>TBL1XR1</i> in Primary Central Nervous System Lymphomas Open
Purpose: Our objective was to identify the genetic changes involved in primary central nervous system lymphoma (PCNSL) oncogenesis and evaluate their clinical relevance.Experimental Design: We investigated a series of 29 newl…
View article: Data from Recurrent Mutations of <i>MYD88</i> and <i>TBL1XR1</i> in Primary Central Nervous System Lymphomas
Data from Recurrent Mutations of <i>MYD88</i> and <i>TBL1XR1</i> in Primary Central Nervous System Lymphomas Open
Purpose: Our objective was to identify the genetic changes involved in primary central nervous system lymphoma (PCNSL) oncogenesis and evaluate their clinical relevance.Experimental Design: We investigated a series of 29 newl…
View article: Supplementary Table 1 from Recurrent Mutations of <i>MYD88</i> and <i>TBL1XR1</i> in Primary Central Nervous System Lymphomas
Supplementary Table 1 from Recurrent Mutations of <i>MYD88</i> and <i>TBL1XR1</i> in Primary Central Nervous System Lymphomas Open
PDF file, 55K, Table S1: Recurrent chromosome region imbalances found in more than 20% of PCNSLs investigated by high resolution genomic arrays.
View article: Supplementary Table 1 from Recurrent Mutations of <i>MYD88</i> and <i>TBL1XR1</i> in Primary Central Nervous System Lymphomas
Supplementary Table 1 from Recurrent Mutations of <i>MYD88</i> and <i>TBL1XR1</i> in Primary Central Nervous System Lymphomas Open
PDF file, 55K, Table S1: Recurrent chromosome region imbalances found in more than 20% of PCNSLs investigated by high resolution genomic arrays.
View article: Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer
Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer Open
View article: High-Accuracy Determination of Microsatellite Instability Compatible with Liquid Biopsies
High-Accuracy Determination of Microsatellite Instability Compatible with Liquid Biopsies Open
Background Microsatellite instability (MSI) has recently emerged as a predictive pan-tumor biomarker of immunotherapy efficacy, stimulating the development of diagnostic tools compatible with large-scale screening of patients. In this cont…
View article: Toxicity of locoregional radiotherapy in combination with bevacizumab in patients with non-metastatic breast cancer (TOLERAB): Final long-term evaluation
Toxicity of locoregional radiotherapy in combination with bevacizumab in patients with non-metastatic breast cancer (TOLERAB): Final long-term evaluation Open
Concurrent B and locoregional RT are associated with acceptable 5-year toxicity in patients with non-metastatic breast cancer. No grade ≥3 toxicity was observed.
View article: Implanted Phrenic Stimulation Impairs Local Diaphragm Myofiber Reinnervation in Amyotrophic Lateral Sclerosis
Implanted Phrenic Stimulation Impairs Local Diaphragm Myofiber Reinnervation in Amyotrophic Lateral Sclerosis Open
International audience
View article: Machine Learning for Better Prognostic Stratification and Driver Gene Identification Using Somatic Copy Number Variations in Anaplastic Oligodendroglioma
Machine Learning for Better Prognostic Stratification and Driver Gene Identification Using Somatic Copy Number Variations in Anaplastic Oligodendroglioma Open
Background 1p/19q-codeleted anaplastic gliomas have variable clinical behavior. We have recently shown that the common 9p21.3 allelic loss is an independent prognostic factor in this tumor type. The aim of this study is to identify less fr…
View article: Cdk4/6 inhibitors and overall survival: power of first-line trials in metastatic breast cancer
Cdk4/6 inhibitors and overall survival: power of first-line trials in metastatic breast cancer Open
Palbociclib, ribociclib, and abemaciclib have been investigated in combination with aromatase inhibitors as first-line therapy for metastatic hormone receptor-positive breast cancer (PALOMA-2, MONALEESA-2 and MONALEESA-7, MONARCH-3 trials,…
View article: A clinical trial combining megakaryocytes and haematopoietic stem cells to promote engraftment after autologous transplantation
A clinical trial combining megakaryocytes and haematopoietic stem cells to promote engraftment after autologous transplantation Open
Nilsson's group first suggested the role of megakaryocytes (MKs) as haematopoietic stem cells (HSCs)-regulating niche cells, reporting that transplanted HSCs with long-term multi-lineage reconstitution capacities preferentially lodged with…
View article: Effect of maternal obesity on birthweight and neonatal fat mass: A prospective clinical trial
Effect of maternal obesity on birthweight and neonatal fat mass: A prospective clinical trial Open
Regardless of gestational diabetes, maternal obesity and insulin resistance were associated with increased adiposity in girls only. Persistence of this sexual dimorphism remains to be explored during infancy.
View article: OS11.3 Machine learning for better prognostic stratification and driver genes identification in 1p/19q-codeleted grade III gliomas
OS11.3 Machine learning for better prognostic stratification and driver genes identification in 1p/19q-codeleted grade III gliomas Open
BACKGROUND: Although major advances have been accomplished over the last years in their characterization, 1p/19q-codeleted anaplastic gliomas have variable clinical behavior and mysterious 1p/19q-codeletion “driven” molecular oncogenesis. …
View article: Cigarette Smoking During Pregnancy: Do Complete Abstinence and Low Level Cigarette Smoking Have Similar Impact on Birth Weight?
Cigarette Smoking During Pregnancy: Do Complete Abstinence and Low Level Cigarette Smoking Have Similar Impact on Birth Weight? Open
As an alternative to quitting smoking, pregnant smokers reduce their smoking rate thinking that this diminishes smoking-related negative health outcomes. No study has established whether low smoking rate (more than 0 but less than 5 cpd) d…
View article: Polyvalent immunoglobulins, platelet lysate and lenalidomide: cocktail for polyfunctional NK cells expansion for multiple myeloma
Polyvalent immunoglobulins, platelet lysate and lenalidomide: cocktail for polyfunctional NK cells expansion for multiple myeloma Open
View article: Correction: Bee Venom for the Treatment of Parkinson Disease – A Randomized Controlled Clinical Trial
Correction: Bee Venom for the Treatment of Parkinson Disease – A Randomized Controlled Clinical Trial Open
[This corrects the article DOI: 10.1371/journal.pone.0158235.].
View article: Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk
Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk Open
PRLRI146L and PRLRI176V variants are not associated with breast cancer or MFA risk. However, one cannot exclude that low but sustained PRLR signaling may facilitate or contribute to pathological development driven by …
View article: Bee Venom for the Treatment of Parkinson Disease – A Randomized Controlled Clinical Trial
Bee Venom for the Treatment of Parkinson Disease – A Randomized Controlled Clinical Trial Open
ClinicalTrials.gov NCT01341431.
View article: Repetitive Transcranial Magnetic Stimulation to Supplementary Motor Area in Refractory Obsessive-Compulsive Disorder Treatment: a Sham-Controlled Trial
Repetitive Transcranial Magnetic Stimulation to Supplementary Motor Area in Refractory Obsessive-Compulsive Disorder Treatment: a Sham-Controlled Trial Open
Low-frequency repetitive transcranial magnetic stimulation applied to the presupplementary area seems ineffective for the treatment of obsessive-compulsive disorder patients, at least in severe and drug-refractory cases such as those inclu…
View article: The Efficacy of Three Modalities of Internet-Based Psychotherapy for Non–Treatment-Seeking Online Problem Gamblers: A Randomized Controlled Trial
The Efficacy of Three Modalities of Internet-Based Psychotherapy for Non–Treatment-Seeking Online Problem Gamblers: A Randomized Controlled Trial Open
ANSM 2013-A00794-41.
View article: Factors associated with experimentation of electronic cigarettes among Parisian teenagers in 2013
Factors associated with experimentation of electronic cigarettes among Parisian teenagers in 2013 Open
Rate of e-cig. experimentation among schoolchildren increased by 8.1 % in 1 year. Non-smoking youth may use e-cig. Prospective studies are urgently needed to assess the evolution of e-cig. use both among smoking and non-smoking youth.
View article: Evaluation of an integrated multidisciplinary approach in multiple sclerosis care: A prospective, randomized, controlled study
Evaluation of an integrated multidisciplinary approach in multiple sclerosis care: A prospective, randomized, controlled study Open
Background Disabled multiple sclerosis (MS) patients often need intervention of multiple specialists, resulting in a complex organization of care. How this multidisciplinary care should be organized and structured has not been studied. Obj…
View article: Endplate denervation correlates with Nogo-A muscle expression in amyotrophic lateral sclerosis patients
Endplate denervation correlates with Nogo-A muscle expression in amyotrophic lateral sclerosis patients Open
Our results support the hypothesis that morphological alterations of NMJs are present from early-stage disease and may significantly contribute to functional motor impairment in ALS patients. Muscle expression of Nogo-A is associated with …