Margaret Johnson
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Establishing Consensus on the Breakthrough Pain Assessment Questionnaire-Self Report (BTPAQ-SR) for Typically Developing Children and Young People (8–25 yrs) with Life-Limiting and Life-Threatening Conditions: An International e-Delphi Study of Expert Healthcare Professionals Open
Background/Objectives: Breakthrough pain (BTP) is commonly experienced by children and young people with life-limiting and life-threatening conditions. While over 50 tools exist for the assessment of breakthrough pain in adults, there is c…
View article: Lung Transplant Outcomes Following Treatment of Pre‐Transplant MAC Pulmonary Infection
Lung Transplant Outcomes Following Treatment of Pre‐Transplant MAC Pulmonary Infection Open
Background Treating Mycobacterium avium complex (MAC) infection pre‐lung transplant (LT) can be challenging to treat, given prolonged therapy and side effects. The impact of pre‐transplant MAC treatment on recurrence and outcomes post‐LT r…
The Role of Healthy Relationships and Social Connectivity in the Mediterranean Lifestyle: An Umbrella Review of Reviews Open
Introduction Social connectivity and interpersonal relationships underpin all aspects of lifestyle. As part of a broader research collaboration on the Mediterranean lifestyle, we examined existing evidence on social connectivity patterns i…
View article: Severe acute respiratory syndrome coronavirus-2 antibody prevalence in adults with HIV
Severe acute respiratory syndrome coronavirus-2 antibody prevalence in adults with HIV Open
Objectives: To measure severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antibody seroprevalence within a cohort of adults with HIV and correlate demographics with response rates to SARS CoV-2 vaccination. Design: Initial vaccin…
View article: A Bayesian hierarchical framework for fusion of remote sensing data: An example with solar-induced fluorescence
A Bayesian hierarchical framework for fusion of remote sensing data: An example with solar-induced fluorescence Open
Solar-induced chlorophyll fluorescence (SIF) has emerged as an effective indicator of vegetation productivity and plant health. The global quantification of SIF and its associated uncertainties yields many important capabilities, including…
Caregiver burden in lung transplantation: A review Open
Caregivers play a pivotal role in supporting patients undergoing lung transplant and often experience significant psychological, physical, and financial burdens. The current literature suggests that caregivers face heightened depression an…
National Survey of Sexual Attitudes and Lifestyles, 2010-2012: Secure Access Open
The British National Surveys of Sexual Attitudes and Lifestyles, or Natsal, are among the largest and most detailed studies of sexual behaviour in the world. Three Natsal surveys have taken place to date: Natsal-1 in 1990-1991 (available f…
View article: Major Depressive Disorder and Driving Behavior Among Older Adults
Major Depressive Disorder and Driving Behavior Among Older Adults Open
Importance Depression and antidepressant use are independently associated with crash risk among older drivers. However, it is unclear what factors impact daily driving that increase safety risk for drivers with depression. Objective To exa…
View article: Exploring the cascade of mental healthcare among people with <scp>HIV</scp> experiencing depressive symptoms in the UK and Ireland: The <scp>POPPY</scp> study
Exploring the cascade of mental healthcare among people with <span>HIV</span> experiencing depressive symptoms in the UK and Ireland: The <span>POPPY</span> study Open
Introduction Depressive symptoms are highly prevalent among people with HIV, which can negatively impact HIV‐related outcomes. We explore the cascade of mental healthcare for people with HIV experiencing depressive symptoms. Methods People…
Unlocking the potential of digital therapeutics: The need for consistent and granular inclusion in drug compendia for managed care Open
The field of digital therapeutics (DTx), software programs that prevent, manage, and treat medical conditions, continues to grow. DTx offers new treatment options and has the potential to close gaps in care caused by unmet patient needs, p…
View article: Footprints of innate immune activity during HIV-1 reservoir cell evolution in early-treated infection
Footprints of innate immune activity during HIV-1 reservoir cell evolution in early-treated infection Open
Antiretroviral treatment (ART) initiation during the early stages of HIV-1 infection is associated with a higher probability of maintaining drug-free viral control during subsequent treatment interruptions, for reasons that remain unclear.…
View article: Clinical characteristics of women with <scp>HIV</scp> in the <scp>RESPOND</scp> cohort: A descriptive analysis and comparison to men
Clinical characteristics of women with <span>HIV</span> in the <span>RESPOND</span> cohort: A descriptive analysis and comparison to men Open
Background Women with HIV are globally underrepresented in clinical research. Existing studies often focus on reproductive outcomes, seldom focus on older women, and are often underpowered to assess sex/gender differences. We describe CD4,…
View article: MAVMET trial: maraviroc and/or metformin for metabolic dysfunction associated fatty liver disease in adults with suppressed HIV
MAVMET trial: maraviroc and/or metformin for metabolic dysfunction associated fatty liver disease in adults with suppressed HIV Open
Objective: Metabolic dysfunction associated fatty liver disease (MAFLD) is over-represented in people with HIV (PWH). Maraviroc (MVC) and/or metformin (MET) may reduce MAFLD by influencing inflammatory pathways and fatty acid metabolism. D…
Impact of using drones in emergency medicine: What does the future hold? Open
The use of unmanned aerial vehicles or “drones” has expanded in the last decade, as their technology has become more sophisticated, and costs have decreased. They are now used routinely in farming, environmental surveillance, public safety…
Drone Delivery of an Automated External Defibrillator Open
To the Editor: Every year, an estimated 350,000 persons in the United States have an out-ofhospital cardiac arrest; only approximately 10% survive.1 The probability of survival doubles when a bystander administers cardiopulmonary resuscita…
View article: Implementation of a transitional care model for stroke: Perspectives from frontline clinicians, administrators, and COMPASS-TC implementation staff
Implementation of a transitional care model for stroke: Perspectives from frontline clinicians, administrators, and COMPASS-TC implementation staff Open
Background and Objectives: Stroke is a chronic, complex condition that disproportionally affects older adults. Health systems are evaluating innovative transitional care (TC) models to improve outcomes in these patients. The Comprehensive …
Post-acute Ambulatory Care Service Use among Patients Discharged Home after Stroke or TIA: The Cluster-randomized COMPASS Study Open
Background and Objectives: We examined transitional care management within 90 days and 1 year following discharge home among acute stroke and transient ischemic attack patients from the Comprehensive Post-Acute Stroke Services (COMPASS) St…
Skilled Nursing and Inpatient Rehabilitation Facility Use by Medicare Fee-for-Service Beneficiaries Discharged Home After a Stroke: Findings From the COMPASS Trial Open
Objectives: To examine the effect of a comprehensive transitional care model on the use of skilled nursing facility (SNF) and inpatient rehabilitation facility (IRF) care in the 12 months after acute care discharge home following stroke; a…
Randomized Pragmatic Trial of Stroke Transitional Care: The COMPASS Study Open
Background The objectives of this study were to develop and test in real-world clinical practice the effectiveness of a comprehensive postacute stroke transitional care (TC) management program. Methods and Results The COMPASS study (Compre…
View article: Improving sexual health through partner notification: the LUSTRUM mixed-methods research Programme including RCT of accelerated partner therapy
Improving sexual health through partner notification: the LUSTRUM mixed-methods research Programme including RCT of accelerated partner therapy Open
Background Sexually transmitted infections disproportionately affect young people and men who have sex with men. Chlamydia is Britain’s most common sexually transmitted infection. Partner notification is a key intervention to reduce transm…
National Survey of Sexual Attitudes and Lifestyles, 2010-2012: Biological Data: Secure Access Open
The British National Surveys of Sexual Attitudes and Lifestyles, or Natsal, are among the largest and most detailed studies of sexual behaviour in the world. Three Natsal surveys have taken place to date: Natsal-1 in 1990-1991 (available f…
A rapid systematic review of breakthrough pain definitions and descriptions Open
Background Breakthrough pain is common in life-limiting conditions and at end-of-life. Despite over 30 years of study, there is little consensus regarding the definition and characteristics of breakthrough pain. Objective This study aims t…