Benjamin Misselwitz
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View article: Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan Open
Recent evidence suggests that the development of gut microbiota during infancy affects several metabolic, immune, and endocrine pathways in humans. An imbalance in gut microbiota diversity or function, also known as dysbiosis, not only aff…
View article: Factors limiting the detection of domestic violence by general practitioners in Yaound: Assessment of knowledge, attitude and practices
Factors limiting the detection of domestic violence by general practitioners in Yaound: Assessment of knowledge, attitude and practices Open
View article: Emergent spatial structure in the gut microbiota is driven by bacterial growth and gut contractions
Emergent spatial structure in the gut microbiota is driven by bacterial growth and gut contractions Open
Spatial structure can determine function and evolution of bacterial communities. The gut microbiota is known to be spatially structured longitudinally along the many meters of the gastrointestinal tract, but micro-scale structure in the gu…
View article: Ultrasound of Bile Ducts—An Update on Measurements, Reference Values, and Their Influencing Factors
Ultrasound of Bile Ducts—An Update on Measurements, Reference Values, and Their Influencing Factors Open
Objective: To provide an overview of the technique and normal values of ultrasound studies of the bile system based on the published literature. Methods: A literature search for ultrasound studies with measurements of the bile ducts in hea…
View article: Portal Hypertension—Noninvasive Multiparametric Ultrasound‐Based Criteria and Measurements
Portal Hypertension—Noninvasive Multiparametric Ultrasound‐Based Criteria and Measurements Open
Portal hypertension, the most common complication in liver cirrhosis, is characterized by a pathologic increase in portal venous pressure. Portal hypertension is defined as a pressure gradient greater than 5 mmHg between the portal vein an…
View article: Gastrointestinal Ultrasound: Measurements and Normal Findings – What Do You Need to Know?
Gastrointestinal Ultrasound: Measurements and Normal Findings – What Do You Need to Know? Open
Background: A standardized examination procedure and correct bowel wall assessment are the prerequisites for correct findings and for distinguishing normal findings from pathological diagnoses. PubMed was searched for the time period from …
View article: Anwendung fortgeschrittener Therapien bei chronisch-entzündlichen Darmerkrankungen
Anwendung fortgeschrittener Therapien bei chronisch-entzündlichen Darmerkrankungen Open
View article: Efficacy and Safety of Anthocyanin-Rich Extract in Patients with Ulcerative Colitis: A Randomized Controlled Trial
Efficacy and Safety of Anthocyanin-Rich Extract in Patients with Ulcerative Colitis: A Randomized Controlled Trial Open
Background: Bilberries are effective in inducing clinical, endoscopic, and biochemical improvement in ulcerative colitis (UC) patients. The aim of this study was to investigate the efficacy of anthocyanin-rich extract (ACRE), the bioactive…
View article: Efficacy and Safety of Anthocyanin-Rich Extract in Patients with Ulcerative Colitis: A Randomized Controlled Trial
Efficacy and Safety of Anthocyanin-Rich Extract in Patients with Ulcerative Colitis: A Randomized Controlled Trial Open
Background: Bilberries are effective in inducing clinical, endoscopic, and biochemical improvement in ulcerative colitis (UC) patients. The aim of this study was to investigate the efficacy of anthocyanin-rich extract (ACRE), the bioactive…
View article: Endoskopische und chirurgische Behandlung intestinaler Stenosen im Zusammenhang mit chronisch-entzündlichen Darmerkrankungen
Endoskopische und chirurgische Behandlung intestinaler Stenosen im Zusammenhang mit chronisch-entzündlichen Darmerkrankungen Open
Zusammenfassung Der Morbus Crohn (MC), eine chronisch-entzündliche Darmerkrankung (CED), ist durch eine übergreifende transmurale Entzündung des Gastrointestinaltrakts gekennzeichnet, die zu entzündlichen und fibrotischen Stenosen führen k…
View article: Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan Open
Recent evidence suggests that the development of gut microbiota during infancy affects several metabolic, immune, and endocrine pathways in humans. An imbalance in gut microbiota diversity or function, also known as dysbiosis, not only af…
View article: <scp>XBB</scp>.1.5‐Adapted <scp>COVID</scp>‐19 <scp>mRNA</scp> Vaccines but Not Infections With Previous Omicron Variants Boost Neutralisation Against the <scp>SARS</scp>‐<scp>CoV</scp>‐2 <scp>JN</scp>.1 Variant in Patients With Inflammatory Bowel Disease
<span>XBB</span>.1.5‐Adapted <span>COVID</span>‐19 <span>mRNA</span> Vaccines but Not Infections With Previous Omicron Variants Boost Neutralisation Against the <span>SARS</span>‐<span>CoV</span>‐2 <span>JN</span>.1 Variant in Patients With Inflammatory Bowel Disease Open
Background Variant‐adapted COVID‐19 vaccines are recommended for patients with inflammatory bowel disease (IBD). However, many patients rely on pre‐existing immunity by original vaccines or prior infections. Aim To assess whether such immu…
View article: Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan Open
Recent evidence suggests that gut microbiota development during infancy impact several metabolic, immune and endocrine pathways in humans. An imbalance in the gut microbiota diversity or function, also known dysbiosis, not only affect earl…
View article: Fecal urgency and incontinence in inflammatory bowel disease perceived by physician and patient: Results from the Swiss fecal urgency survey
Fecal urgency and incontinence in inflammatory bowel disease perceived by physician and patient: Results from the Swiss fecal urgency survey Open
Introduction Although increasingly appreciated, little is known about the prevalence of fecal urgency, fecal incontinence and differences between patients' and physicians' perception in inflammatory bowel disease (IBD). Methods We performe…
View article: Comments and illustrations of the European Federation of Societies for Ultrasound in Medicine contrast-enhanced ultrasound guidelines: Multiparametric imaging and EUS-guided sampling in rare pancreatic tumors. Benign mesenchymal pancreatic tumors
Comments and illustrations of the European Federation of Societies for Ultrasound in Medicine contrast-enhanced ultrasound guidelines: Multiparametric imaging and EUS-guided sampling in rare pancreatic tumors. Benign mesenchymal pancreatic tumors Open
The focus of the review is on primary benign mesenchymal pancreatic tumors and their imaging appearance. These tumors are extremely rare. Usually, they are not diagnosed until postoperative histology is available, and so even benign tumors…
View article: Associations between gut microbiota characteristics and non‐motor symptoms following pharmacological and surgical treatments in Parkinson's disease patients
Associations between gut microbiota characteristics and non‐motor symptoms following pharmacological and surgical treatments in Parkinson's disease patients Open
Background The gut microbiota has been implicated in Parkinson's disease (PD), with alterations observed in microbial composition and reduced microbial species richness, which may influence gastrointestinal symptoms in PD patients. It rema…
View article: Optimal timing of a colonoscopy screening schedule depends on adenoma detection, adenoma risk, adherence to screening and the screening objective: A microsimulation study
Optimal timing of a colonoscopy screening schedule depends on adenoma detection, adenoma risk, adherence to screening and the screening objective: A microsimulation study Open
Colonoscopy-based screening provides protection against colorectal cancer (CRC), but the optimal starting age and time intervals of screening colonoscopies are unknown. We aimed to determine an optimal screening schedule for the US populat…
View article: Comments and Illustrations of Ultrasound Findings in Extrapulmonary Tuberculosis Manifestations
Comments and Illustrations of Ultrasound Findings in Extrapulmonary Tuberculosis Manifestations Open
This review describes the appearance of extrapulmonary tuberculosis manifestations in comprehensive and multiparametric ultrasound imaging. The aim is to increase awareness of typical ultrasound findings regarding extrapulmonary tuberculos…
View article: Comments and illustrations of the European Federation of Societies for Ultrasound in Medicine guidelines: Rare pancreatic tumors, ultrasound and contrast-enhanced ultrasound features—Malignant mesenchymal tumors
Comments and illustrations of the European Federation of Societies for Ultrasound in Medicine guidelines: Rare pancreatic tumors, ultrasound and contrast-enhanced ultrasound features—Malignant mesenchymal tumors Open
Rare malignant mesenchymal pancreatic tumors are systematized and reported in this review. The focus is on the appearance on imaging. The present overview summarizes the data and shows that not every pancreatic tumor corresponds to the mos…
View article: Development of non-alcoholic steatohepatitis is associated with gut microbiota but not with oxysterol enzymes CH25H, EBI2, or CYP7B1 in mice
Development of non-alcoholic steatohepatitis is associated with gut microbiota but not with oxysterol enzymes CH25H, EBI2, or CYP7B1 in mice Open
View article: Refining the Concept of Microscopic Colitis: HLA Signatures Discriminating Collagenous and Lymphocytic Colitis
Refining the Concept of Microscopic Colitis: HLA Signatures Discriminating Collagenous and Lymphocytic Colitis Open
View article: P266 Predictive tissue-based biomarkers in treatment of Inflammatory Bowel Disease with biologicals and small molecules: a systematic review
P266 Predictive tissue-based biomarkers in treatment of Inflammatory Bowel Disease with biologicals and small molecules: a systematic review Open
Background The treatment landscape of inflammatory bowel disease (IBD) has changed in the past decade with introduction of new drug classes. For most drugs, only 30% of patients achieve long-term remission. Clinical implementation of predi…
View article: Treatment of Crohn’s disease with complex fistula disease using an exclusion diet
Treatment of Crohn’s disease with complex fistula disease using an exclusion diet Open
Exclusive Enteral Nutrition (EEN) is considered the standard of care for the treatment of children with Crohns Disease (CD) but it is rarely used in adults. The main reason for this might be severe dietary restrictions, resulting in a redu…
View article: Childlessness in Patients with Inflammatory Bowel Disease – Data from the Prospective Multi-center Swiss IBD Cohort Study
Childlessness in Patients with Inflammatory Bowel Disease – Data from the Prospective Multi-center Swiss IBD Cohort Study Open
Background and Aims: Childlessness and infertility represent a frequent and important issue in inflammatory bowel disease (IBD) patients. Nevertheless, until now epidemiological data remains scarce. Therefore, main objectives of this study…
View article: Immune activation and inflammation in lactating women on combination antiretroviral therapy: role of gut dysfunction and gut microbiota imbalance
Immune activation and inflammation in lactating women on combination antiretroviral therapy: role of gut dysfunction and gut microbiota imbalance Open
Introduction Combination antiretroviral therapy (cART) effectively controls HIV; however, chronic low-level viremia and gut microbiota dysbiosis remain significant drivers of gut and systemic inflammation. In this study, we explored the re…
View article: The Bern Birth Cohort (BeBiCo) to study the development of the infant intestinal microbiota in a high-resource setting in Switzerland: rationale, design, and methods
The Bern Birth Cohort (BeBiCo) to study the development of the infant intestinal microbiota in a high-resource setting in Switzerland: rationale, design, and methods Open
Background Microbiota composition is fundamental to human health with the intestinal microbiota undergoing critical changes within the first two years of life. The developing intestinal microbiota is shaped by maternal seeding, breast milk…
View article: Benchmarking microbial DNA enrichment protocols from human intestinal biopsies
Benchmarking microbial DNA enrichment protocols from human intestinal biopsies Open
Shotgun metagenomic sequencing is a powerful tool for studying bacterial communities in their natural habitats or sites of infection, without the need for cultivation. However, low microbial signals in metagenomic sequencing can be overwhe…
View article: Antenatal gut microbiome profiles and effect on pregnancy outcome in HIV infected and HIV uninfected women in a resource limited setting
Antenatal gut microbiome profiles and effect on pregnancy outcome in HIV infected and HIV uninfected women in a resource limited setting Open
View article: Because I’m happy – positive affect and its predictive value for future disease activity in patients with inflammatory bowel diseases: a retrospective cohort study
Because I’m happy – positive affect and its predictive value for future disease activity in patients with inflammatory bowel diseases: a retrospective cohort study Open
Background: While the detrimental impact of negative emotions on the clinical course of inflammatory bowel disease (IBD) and quality of life has been extensively investigated, evidence for a potential impact of positive emotions is scarce.…
View article: Development of non-alcoholic steatohepatitis is associated with gut microbiota but not oxysterol synthesis
Development of non-alcoholic steatohepatitis is associated with gut microbiota but not oxysterol synthesis Open
Liver steatosis is the most frequent liver disorder and its advanced stage, non-alcoholic steatohepatitis (NASH), will soon become the main reason for liver fibrosis and cirrhosis. The “multiple hits hypothesis” suggests that progression f…