Maria Plesa
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View article: The effect of dose-interval on antibody response to mRNA COVID-19 vaccines: a prospective cohort study
The effect of dose-interval on antibody response to mRNA COVID-19 vaccines: a prospective cohort study Open
Background Vaccination against COVID-19 is highly effective in preventing severe disease and hospitalization, but primary COVID mRNA vaccination schedules often differed from those recommended by the manufacturers due to supply chain issue…
View article: Vitamin D3 Attenuates Viral-Induced Inflammation and Fibrotic Responses in Bronchial Smooth Muscle Cells
Vitamin D3 Attenuates Viral-Induced Inflammation and Fibrotic Responses in Bronchial Smooth Muscle Cells Open
Toll-like receptor 3 (TLR3) activation by viral infections plays a key role in promoting inflammatory immune responses that contribute to pulmonary fibrosis in chronic inflammatory respiratory diseases. Vitamin D3 has been shown to be bene…
View article: <p>Action of 1,25(OH)<sub>2</sub>D<sub>3</sub> on Human Asthmatic Bronchial Fibroblasts: Implications for Airway Remodeling in Asthma</p>
Action of 1,25(OH)<sub>2</sub>D<sub>3</sub> on Human Asthmatic Bronchial Fibroblasts: Implications for Airway Remodeling in Asthma Open
DHBFCs under TGF-β1 or TNF-α-IL-1β stimulation showed higher fibrogenic capacity when compared to NHBFCs. 1,25(OH)2D3 significantly blocked these effects and highlight 1,25(OH)2D3 as a possible therapeutic target for severe asthma.
View article: Action of 1,25(OH)2D3 on Human Asthmatic Bronchial Fibroblasts: Implications for Airway Remodeling in Asthma
Action of 1,25(OH)2D3 on Human Asthmatic Bronchial Fibroblasts: Implications for Airway Remodeling in Asthma Open
Maria Plesa,1 Mellissa Gaudet,1 Andrea Mogas,1 Ronald Olivenstein,1,2 Saba Al Heialy,1,3 Qutayba Hamid1,2,4 1Translational Research in Respiratory Diseases, Meakins-Christie Laboratories, Research Institute of the McGill University Health …
View article: Genes Identified Through Genome-wide Association Studies of Osteonecrosis in Childhood Acute Lymphoblastic Leukemia Patients
Genes Identified Through Genome-wide Association Studies of Osteonecrosis in Childhood Acute Lymphoblastic Leukemia Patients Open
Aim: To evaluate top-ranking genes identified through genome-wide association studies for an association with corticosteroid-related osteonecrosis in children with acute lymphoblastic leukemia (ALL) who received Dana-Farber Cancer Institut…
View article: Genetic predisposition to corticosteroid : related complications of childhood Acute Lymphoblastic Leukemia (cALL) treatment
Genetic predisposition to corticosteroid : related complications of childhood Acute Lymphoblastic Leukemia (cALL) treatment Open
L’ostéonécrose (ON) et les fractures (FR) sont des complications qui prennent de plus en plus place dans le traitement pédiatrique de la leucémie aiguë lymphoblastique (LAL). L’ON peut être causée par différents facteurs, dont principaleme…