Martha María Téllez‐Rojo
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View article: Impact of a Prenatal Exposure Mixture of Metals on DNA Methylation-derived Cell-Type Composition in Cord Blood
Impact of a Prenatal Exposure Mixture of Metals on DNA Methylation-derived Cell-Type Composition in Cord Blood Open
Background Metal(loid) exposure can exert immunotoxic effects, including changes in white blood cell proportions. The impact from metal exposure mixtures during pregnancy has not been examined in relation to cell-type composition at birth.…
View article: Prenatal exposure to metal(loid)s mixture and childhood lung function: Exploring sex-specific associations
Prenatal exposure to metal(loid)s mixture and childhood lung function: Exploring sex-specific associations Open
Background: The link between prenatal exposure to metal(loid)s and childhood lung function, including sex-specific effects, has not been completely elucidated. We aimed to examine sex-specific individual and joint effects of prenatal metal…
View article: Associations between prenatal metal mixtures and allergic symptoms in childhood
Associations between prenatal metal mixtures and allergic symptoms in childhood Open
Previous work has linked exposure to individual metals in pregnancy to allergic outcomes postnatally but few studies have examined metals exposure as a mixture. Analysis included 542 mother-child dyads enrolled in the Programming Research …
View article: Air pollution, temperature, and HbA1c levels among children in Mexico City, Mexico
Air pollution, temperature, and HbA1c levels among children in Mexico City, Mexico Open
Glycated hemoglobin (HbA1c), a strong indicator of diabetes, is affected by air pollution and temperature exposures. However, studies examining the association between HbA1c, temperature, fine particulate matter (PM2.5), and nitrogen dioxi…
View article: Performance of an automated sleep scoring approach for actigraphy data in children and adolescents
Performance of an automated sleep scoring approach for actigraphy data in children and adolescents Open
Study Objectives GGIR is an R package for processing raw acceleration data to estimate sleep health parameters. We aimed to (1) assess the performance of three sleep algorithms within GGIR against PSG for detecting sleep/wake in clinically…
View article: Associations Between Prenatal Phthalate Exposure and Atopic Symptoms in Childhood: Effect Modification by Child Sex
Associations Between Prenatal Phthalate Exposure and Atopic Symptoms in Childhood: Effect Modification by Child Sex Open
Background: The global rise in atopic diseases, like atopic dermatitis and allergic rhinitis, may be linked to prenatal exposure to endocrine-disrupting chemicals like phthalates, with potential sex-specific effects. Methods: We analyzed 5…
View article: Sleep Duration Modifies the Association of the Alternate Mediterranean Diet Score With Metabolic Syndrome in Midlife Women in Mexico
Sleep Duration Modifies the Association of the Alternate Mediterranean Diet Score With Metabolic Syndrome in Midlife Women in Mexico Open
Associations between diet and MetS are only observed in the presence of inadequate sleep duration, suggesting a potential interaction that warrants further investigation through longitudinal research.
View article: Adolescent dietary patterns and methyl-donor nutrient intakes in relation to blood leukocyte DNA methylation of circadian genes
Adolescent dietary patterns and methyl-donor nutrient intakes in relation to blood leukocyte DNA methylation of circadian genes Open
Dietary composition may impact circadian rhythms, potentially through DNA methylation of circadian genes. However, research among adolescents remains limited. Cross-sectional association of three dietary patterns, derived from principal co…
View article: Essential and non-essential metals in children’s intellectual functioning: A multi-media biomarker approach from a Mexico City birth cohort
Essential and non-essential metals in children’s intellectual functioning: A multi-media biomarker approach from a Mexico City birth cohort Open
Our study adds to the current body of literature about the co-pollutant confounding problem of evaluating metals and children's intellectual functioning, as well as the effect of understudied toxic metals of public health interest, such as…
View article: Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children
Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children Open
Lead (Pb) is a potent neurotoxicant, but few studies have evaluated its effect on neurobehavioral measures that can be used in multiple species including humans. We investigated the effect of prenatal and childhood Pb exposure on children’…
View article: Newborn mitochondrial DNA copy number is associated with changes to DNA methylation that persist into childhood and are associated with cognitive development
Newborn mitochondrial DNA copy number is associated with changes to DNA methylation that persist into childhood and are associated with cognitive development Open
In newborns, mtDNA-CN was associated with DNAm in mitochondria-related genes and throughout the genome, several of which remained associated in childhood, were associated with child memory scales, and were replicated in a US-based cohort. …
View article: Intermittent Water Supply and Beverage Consumption Patterns among Adolescents and Adults in Mexico: A Nationally Representative, Cross-Sectional Analysis
Intermittent Water Supply and Beverage Consumption Patterns among Adolescents and Adults in Mexico: A Nationally Representative, Cross-Sectional Analysis Open
Our findings suggest an association between IWS and consumption of industrialized beverages, and thus its potential contribution to chronic disease risk.
View article: Concentrations of Heavy Metals in Processed Baby Foods and Infant Formulas Worldwide: A Scoping Review
Concentrations of Heavy Metals in Processed Baby Foods and Infant Formulas Worldwide: A Scoping Review Open
The aim of this study was to synthesize the global evidence of heavy metal (HM) concentrations in baby foods and infant formulas. The toxic HMs lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) have been detected in baby foods and in…
View article: Influence of Overweight and Obesity on Bone Remodeling during Pregnancy
Influence of Overweight and Obesity on Bone Remodeling during Pregnancy Open
Background The prevalence of maternal overweight and obesity during pregnancy continues to increase. Less is known on how this can influence bone health. The aim of this study was to evaluate the association between body mass index (BMI) a…
View article: Association Between Change in the Global Diet Quality Score (GDQS) and Adiposity Change From 2 to 7 Years of Age Among Mexicans
Association Between Change in the Global Diet Quality Score (GDQS) and Adiposity Change From 2 to 7 Years of Age Among Mexicans Open
Overweight and obesity affects approximately 20%-30% of preschool- and school-aged children in Mexico. The GDQS has been proposed as a global metric for monitoring nutrient adequacy in populations, but data for its association with adiposi…
View article: 0299 Sleep Timing and Social Jet Lag Are Associated with Circadian Gene Expression: A Cross-sectional Study in Mexico City Adolescents
0299 Sleep Timing and Social Jet Lag Are Associated with Circadian Gene Expression: A Cross-sectional Study in Mexico City Adolescents Open
Introduction Circadian disruption has been linked to adverse metabolic health, potentially mediated through altered expression of circadian genes. Adolescents are particularly susceptible to circadian disruptors, such as delayed sleep onse…
View article: Dietary Fluoride Exposure During Early Childhood and Its Association with Dental Fluorosis in a Sample of Mexican Adolescents
Dietary Fluoride Exposure During Early Childhood and Its Association with Dental Fluorosis in a Sample of Mexican Adolescents Open
Dental fluorosis indicates past fluoride intake. People living in Mexico City are exposed to fluoridated salt, which contributes significantly to fluoride intake. This study aimed to (1) estimate fluoride intake during early childhood and …
View article: Associations of Prenatal Socioeconomic Status and Childhood Working Memory: A Structural Equation Modeling Approach
Associations of Prenatal Socioeconomic Status and Childhood Working Memory: A Structural Equation Modeling Approach Open
Objective: To determine if prenatal socioeconomic status (SES) is associated with childhood working memory (WM), we constructed a more precise, integrative measure of WM using variables from multiple tasks that may provide a more represent…
View article: Sleep timing and duration in relation to blood leukocyte DNA methylation in adolescents: an epigenome-wide analysis
Sleep timing and duration in relation to blood leukocyte DNA methylation in adolescents: an epigenome-wide analysis Open
Study Objectives To investigate associations between adolescent sleep duration and timing, and blood leukocyte DNA methylation, one type of epigenetic modification that may respond to changes in sleep. Methods Cross-sectional epigenome-wid…