Mina Aleksanyan
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View article: Photoswitchable Endocytosis of Biomolecular Condensates in Giant Vesicles
Photoswitchable Endocytosis of Biomolecular Condensates in Giant Vesicles Open
Interactions between membranes and biomolecular condensates can give rise to complex phenomena such as wetting transitions, mutual remodeling, and endocytosis. In this study, light‐triggered manipulation of condensate engulfment is demonst…
View article: Photoswitchable endocytosis of biomolecular condensates in giant vesicles
Photoswitchable endocytosis of biomolecular condensates in giant vesicles Open
Interactions between membranes and biomolecular condensates can give rise to complex phenomena such as wetting transitions, mutual remodeling, and endocytosis. In this study, we demonstrate a light-triggered manipulation of condensate engu…
View article: Photomanipulation of Minimal Synthetic Cells: Area Increase, Softening, and Interleaflet Coupling of Membrane Models Doped with Azobenzene‐Lipid Photoswitches
Photomanipulation of Minimal Synthetic Cells: Area Increase, Softening, and Interleaflet Coupling of Membrane Models Doped with Azobenzene‐Lipid Photoswitches Open
Light can effectively interrogate biological systems in a reversible and physiologically compatible manner with high spatiotemporal precision. Understanding the biophysics of photo‐induced processes in bio‐systems is crucial for achieving …
View article: Kinetic relaxation of giant vesicles validates diffusional softening in a binary lipid mixture
Kinetic relaxation of giant vesicles validates diffusional softening in a binary lipid mixture Open
The stiffness of biological membranes determines the work required by cellular machinery to form and dismantle vesicles and other lipidic shapes. Model membrane stiffness can be determined from the equilibrium distribution of giant unilame…
View article: Photomanipulation of minimal synthetic cells: area increase, softening and interleaflet coupling of membrane models doped with azobenzene-lipid photoswitches
Photomanipulation of minimal synthetic cells: area increase, softening and interleaflet coupling of membrane models doped with azobenzene-lipid photoswitches Open
Light can effectively interrogate biological systems in a reversible and physiologically compatible manner with high spatiotemporal precision. Understanding the biophysics of photo-induced processes in bio-systems is crucial for achieving …
View article: Assessing membrane material properties from the response of giant unilamellar vesicles to electric fields
Assessing membrane material properties from the response of giant unilamellar vesicles to electric fields Open
Knowledge of the material properties of membranes is crucial to understanding cell viability and physiology. A number of methods have been developed to probe membranes in vitro, utilizing the response of minimal biomimetic membrane models …
View article: Kinetic relaxation of giant vesicles validates diffusional softening in a binary lipid mixture
Kinetic relaxation of giant vesicles validates diffusional softening in a binary lipid mixture Open
The stiffness of biological membranes determines the work required by cellular machinery to form and dismantle vesicles and other lipidic shapes. Model membrane stiffness can be determined from the equilibrium distribution of giant unilame…
View article: Zwitterionic Dendrimersomes: A Closer Xenobiotic Mimic of Cell Membranes
Zwitterionic Dendrimersomes: A Closer Xenobiotic Mimic of Cell Membranes Open
Building functional mimics of cell membranes is an important task toward the development of synthetic cells. So far, lipid and amphiphilic block copolymers are the most widely used amphiphiles with the bilayers by the former lacking stabil…
View article: Characterization of DAG Binding to TRPC Channels by Target-Dependent cis–trans Isomerization of OptoDArG
Characterization of DAG Binding to TRPC Channels by Target-Dependent cis–trans Isomerization of OptoDArG Open
Azobenzene-based photochromic lipids are valuable probes for the analysis of ion channel–lipid interactions. Rapid photoisomerization of these molecules enables the analysis of lipid gating kinetics and provides information on lipid sensin…
View article: GM1 asymmetry in the membrane stabilizes pores
GM1 asymmetry in the membrane stabilizes pores Open
View article: Glycopolymer Based LbL Multilayer Thin Films with Embedded Liposomes
Glycopolymer Based LbL Multilayer Thin Films with Embedded Liposomes Open
Layer‐by‐layer (LbL) self‐assembly emerged as an efficient technique for fabricating coating systems for, e.g., drug delivery systems with great versatility and control. In this work, protecting group free and aqueous‐based syntheses of bi…
View article: GM1 asymmetry in the membrane stabilizes pores
GM1 asymmetry in the membrane stabilizes pores Open
Cell membranes are highly asymmetric and their stability against poration is crucial for survival. We investigated the influence of membrane asymmetry on electroporation of giant unilamellar vesicles with membranes doped with GM1, a gangli…
View article: Effects of Solution Conductivity on Macropore Size Dynamics in Electroporated Lipid Vesicle Membranes
Effects of Solution Conductivity on Macropore Size Dynamics in Electroporated Lipid Vesicle Membranes Open
View article: CCDC 2097845: Experimental Crystal Structure Determination
CCDC 2097845: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: GM1 Leaflet Asymmetry Stabilizes Membrane Pores
GM1 Leaflet Asymmetry Stabilizes Membrane Pores Open
View article: Perfluorinated Ligands Induce Meridional Metal Stereochemistry to Generate M<sub>8</sub>L<sub>12</sub>, M<sub>10</sub>L<sub>15</sub>, and M<sub>12</sub>L<sub>18</sub> Prisms
Perfluorinated Ligands Induce Meridional Metal Stereochemistry to Generate M<sub>8</sub>L<sub>12</sub>, M<sub>10</sub>L<sub>15</sub>, and M<sub>12</sub>L<sub>18</sub> Prisms Open
Meridional (mer) coordination promotes the generation of larger and lower-symmetry prismatic metallosupramolecular structures, in contrast with the facial (fac) coordination common to smaller and higher-symmetry polyhedra. Here, we describ…
View article: CCDC 1442991: Experimental Crystal Structure Determination
CCDC 1442991: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1442989: Experimental Crystal Structure Determination
CCDC 1442989: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1442990: Experimental Crystal Structure Determination
CCDC 1442990: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1442988: Experimental Crystal Structure Determination
CCDC 1442988: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …