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View article: Multicenter study on the diagnostic accuracy of left ventricular hypertrophy using a fully automated echocardiographic analysis system with artificial intelligence
Multicenter study on the diagnostic accuracy of left ventricular hypertrophy using a fully automated echocardiographic analysis system with artificial intelligence Open
Background A fully automated echocardiographic analysis system utilizing artificial intelligence was provided. It enables to generate diagnostic reports based on guidelines through zero-click measurements. While the system is expected to s…
View article: Elevated left atrial stiffness index is a poor prognostic factor in heart failure with preserved ejection fraction undergoing transcatheter aortic valve replacement
Elevated left atrial stiffness index is a poor prognostic factor in heart failure with preserved ejection fraction undergoing transcatheter aortic valve replacement Open
Background Patients with severe aortic valve stenosis undergoing transcatheter aortic valve replacement (TAVR) present with a high prevalence of heart failure with preserved ejection fraction (HFpEF). An elevated left atrial stiffness inde…
View article: Prognostic utility of non-invasive left atrial stiffness index in patients with heart failure with preserved ejection fraction: insights from EASY-HFpEF study
Prognostic utility of non-invasive left atrial stiffness index in patients with heart failure with preserved ejection fraction: insights from EASY-HFpEF study Open
Background It is known that an increase left atrial stiffness is associated with poor prognosis in patients with heart failure with preserved ejection fraction (HFpEF). Purpose We evaluated the predictive utility of non-invasive left atria…
View article: Drug-coated balloon versus drug-eluting stent for de novo culprit lesion in acute coronary syndromes: a report from nationwide registry in japan
Drug-coated balloon versus drug-eluting stent for de novo culprit lesion in acute coronary syndromes: a report from nationwide registry in japan Open
Background Randomized trials have demonstrated the non-inferiority of DCB strategy compared to DES strategy for ACS [1-3]. However, generalizability in clinical settings remains unclear. Purpose This study aims to compare the outcomes betw…
View article: Evaluation of Medication Adherence Among Prevalent Users in Hypertension, Dyslipidemia, and Diabetes Using Health Insurance Claims: A Population‐Based Cohort Study in Japan
Evaluation of Medication Adherence Among Prevalent Users in Hypertension, Dyslipidemia, and Diabetes Using Health Insurance Claims: A Population‐Based Cohort Study in Japan Open
Purpose Hypertension (HT), dyslipidemia (DL), and diabetes mellitus (DM) are major risk factors for cardiovascular diseases. Despite the wide availability of medications to reduce this risk, poor adherence to medications remains an issue. …
View article: Serum anti‑KIAA0513 antibody as a common biomarker for mortal atherosclerotic and cancerous diseases
Serum anti‑KIAA0513 antibody as a common biomarker for mortal atherosclerotic and cancerous diseases Open
Numerous antibody biomarkers have been reported for cancer and atherosclerosis-related diseases. The major complications of atherosclerosis and diabetes mellitus (DM) are acute ischemic stroke (AIS), cardiovascular disease (CVD) and chroni…
View article: Dietary intake of folate, vitamin B6, vitamin B12, and riboflavin and the risk of incident dementia
Dietary intake of folate, vitamin B6, vitamin B12, and riboflavin and the risk of incident dementia Open
Background/Objectives: Low intake of B-vitamins may increase dementia; However, epidemiological evidence, particularly for riboflavin (vitamin B₂), remains sparse. The aim of this study was to examine the association between dietary intake…
View article: Association of Nonalcoholic Fatty Liver Disease with Arterial Stiffness and its Metabolomic Profiling in Japanese Community-Dwellers
Association of Nonalcoholic Fatty Liver Disease with Arterial Stiffness and its Metabolomic Profiling in Japanese Community-Dwellers Open
NAFLD was associated with a marker of atherosclerosis, and several metabolites related to insulin resistance, including BCAAs and AAAs, could be involved in the process by which NAFLD leads to atherosclerosis.
View article: Study Profile of the Tsuruoka Metabolomics Cohort Study (TMCS)
Study Profile of the Tsuruoka Metabolomics Cohort Study (TMCS) Open
The Tsuruoka Metabolomics Cohort Study (TMCS) is an ongoing population-based cohort study being conducted in the rural area of Yamagata Prefecture, Japan. This study aimed to enhance the precision prevention of multi-factorial, complex dis…
View article: Metabolomics Profiles Alterations in Cigarette Smokers and Heated Tobacco Product Users
Metabolomics Profiles Alterations in Cigarette Smokers and Heated Tobacco Product Users Open
Our study showed that the glutamate pathway is affected by habitual smoking. These changes in the glutamate pathway may partly explain the mechanism by which cigarette smoking causes cardiovascular disease. HTP use was also associated with…
View article: IkBz is an inhibitor of the serine/threonine kinase and liquid-liquid phase separation that causes transition from adaptive cardiac hypertrophy to heart failure during pressure overload
IkBz is an inhibitor of the serine/threonine kinase and liquid-liquid phase separation that causes transition from adaptive cardiac hypertrophy to heart failure during pressure overload Open
Background and Purpose Inflammation contributes to both adaptive cardiac hypertrophy and heart failure. However, how inflammation causes transition from compensatory response to heart failure remains largely unknown. IkBz is a transcriptio…
View article: Two-year outcomes of drug-coated balloon only strategy for de novo lesions in large coronary vessels
Two-year outcomes of drug-coated balloon only strategy for de novo lesions in large coronary vessels Open
Background Drug-coated balloons (DCB) are effective for the treatment of in-stent restenosis and de novo lesions in small coronary vessels (reference vessel diameter: RVD < 3.0 mm). Recently, several studies have reported acceptable res…
View article: Facial sporotrichosis and chromoblastomycosis In Madagascar: serial cases
Facial sporotrichosis and chromoblastomycosis In Madagascar: serial cases Open
Objective our study aims to determine the epidemiological and clinical management of deep facial mycosis cases. Methods We have conducted a prospective descriptive study of facial sporotrichosis and chromoblastomycosis cases at the two der…
View article: Utility of atherosclerosis-associated serum antibodies against colony-stimulating factor 2 in predicting the onset of acute ischemic stroke and prognosis of colorectal cancer
Utility of atherosclerosis-associated serum antibodies against colony-stimulating factor 2 in predicting the onset of acute ischemic stroke and prognosis of colorectal cancer Open
Introduction Autoantibodies against inflammatory cytokines may be used for the prevention of atherosclerosis. Preclinical studies consider colony-stimulating factor 2 (CSF2) as an essential cytokine with a causal relationship to atheroscle…
View article: The association between sleep parameters and sarcopenia in Japanese community-dwelling older adults
The association between sleep parameters and sarcopenia in Japanese community-dwelling older adults Open
Long sleep was associated with sarcopenia, including LMS and LPP. However, in long sleepers, insomnia was not associated with sarcopenia or any of its components.
View article: Correction to: Determinants of double product: a cross-sectional study of urban residents in Japan
Correction to: Determinants of double product: a cross-sectional study of urban residents in Japan Open
After the publication of this article [1], it was discovered that there was a typo in one sentence of the discussion.Therefore, we will correct it as follows.On line 47 of the discussion, it says "This is equivalent to playing tennis for a…
View article: Determinants of double product: a cross-sectional study of urban residents in Japan
Determinants of double product: a cross-sectional study of urban residents in Japan Open
High DP values at rest were associated with insulin resistance, gamma-glutamyl transferase, and the amount of exercise in participants without underlying disease.
View article: Accumulated unhealthy behaviours and insomnia in Japanese dwellers with and without cardiovascular risk factors: a cross-sectional study
Accumulated unhealthy behaviours and insomnia in Japanese dwellers with and without cardiovascular risk factors: a cross-sectional study Open
Objectives To date, the association between accumulated unhealthy behaviours and insomnia in individuals stratified according to the presence or absence of major cardiovascular risk factors is unclear. This study aimed to examine the effec…
View article: Trends in Prevalence, Treatment, and Control of Hypertension According to 40-Year-Old Life Expectancy at Prefectures in Japan from the National Health and Nutrition Surveys
Trends in Prevalence, Treatment, and Control of Hypertension According to 40-Year-Old Life Expectancy at Prefectures in Japan from the National Health and Nutrition Surveys Open
The prevalence of hypertension has been decreasing in Japan due to improved medical treatment and a decrease in dietary salt intake. However, disparities in the prevalence, treatment, and control of hypertension are expected to occur in di…
View article: A preliminary study of the safety and effectiveness of isoproterenol loading transesophageal echocardiography in atrial fibrillation
A preliminary study of the safety and effectiveness of isoproterenol loading transesophageal echocardiography in atrial fibrillation Open
Funding Acknowledgements Type of funding sources: None. Background In patients with sludge or severe spontaneous echo contrast (SEC) in the left atrial appendage (LAA), isoproterenol loading transesophageal echocardiography (ISP-TEE) has b…
View article: Prediction of Lifetime Risk of Cardiovascular Disease Deaths Stratified by Sex in the Japanese Population
Prediction of Lifetime Risk of Cardiovascular Disease Deaths Stratified by Sex in the Japanese Population Open
Background Lifetime risk is an informative estimate for driving lifestyle and behavioral changes especially for young adults. The impact of composite risk factors for cardiovascular disease on lifetime risk stratified by sex has not been i…
View article: Breastfeeding in Infancy in Relation to Subsequent Physical Size: A 20-year Follow-up of the Ibaraki Children’s Cohort Study (IBACHIL)
Breastfeeding in Infancy in Relation to Subsequent Physical Size: A 20-year Follow-up of the Ibaraki Children’s Cohort Study (IBACHIL) Open
Breastfeeding may prevent overweight in childhood, but its impact is not significant in adolescence and adulthood.
View article: 874Impact of overweight on diabetes prevalence: 20-year trends in National Health and Nutrition Survey, Japan
874Impact of overweight on diabetes prevalence: 20-year trends in National Health and Nutrition Survey, Japan Open
Background Increasing trend of diabetes is significant public health threats. This is a consecutive cross-sectional study aimed to estimate the attribution of overweight for diabetes prevalence in Japan. Methods We used individual data age…
View article: 697Change of smoking habits by introducing and spreading heated tobacco products in Japan
697Change of smoking habits by introducing and spreading heated tobacco products in Japan Open
Background Heated tobacco product (HTP) users are rapidly increasing in Japan since 2014. Controlling HTPs is now one of the most urgent issues. We aimed to clarify the change of smoking habits by introducing and spreading HTPs. Methods We…
View article: 990Seaweed intake and risk of cardiovascular disease: the Japan Public Health Center–based Prospective (JPHC) Study
990Seaweed intake and risk of cardiovascular disease: the Japan Public Health Center–based Prospective (JPHC) Study Open
Background The minerals, vitamins, soluble dietary fibers, and flavonoids of seaweed are protective for preventing cardiovascular diseases. However, the association between seaweed intake and risk of cardiovascular disease has not been est…
View article: Erratum to “Validity Assessment of Self-reported Medication Use for Hypertension, Diabetes, and Dyslipidemia in a Pharmacoepidemiologic Study by Comparison With Health Insurance Claims” [J Epidemiol 31 (9) (2021) 495–502]
Erratum to “Validity Assessment of Self-reported Medication Use for Hypertension, Diabetes, and Dyslipidemia in a Pharmacoepidemiologic Study by Comparison With Health Insurance Claims” [J Epidemiol 31 (9) (2021) 495–502] Open
1 some of the generic names and their Anatomical Therapeutic Chemical (ATC) codes were incorrectly stated in eTable 1, eTable 2, and eTable 3. Some of the generic names and their ATC codes have been added or deleted.Additionally, some of t…