Sana M. Al‐Khatib
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View article: Sudden cardiac arrest: Limitations in risk-stratification and treatment, and the potential for digital technologies and artificial intelligence to improve prediction and outcomes
Sudden cardiac arrest: Limitations in risk-stratification and treatment, and the potential for digital technologies and artificial intelligence to improve prediction and outcomes Open
Sudden cardiac death (SCD) remains a pervasive public health challenge, accounting for a significant proportion of cardiac and all-cause mortality worldwide. Despite notable advancements in cardiovascular therapies and reductions in overal…
View article: Characterization of Septal Scar After Left Bundle Branch Area Pacemaker Implantation
Characterization of Septal Scar After Left Bundle Branch Area Pacemaker Implantation Open
Background Left bundle branch area pacing (LBBAP) is increasingly used in patients with a ventricular pacing indication but necessitates precise septal localization. The resulting effects of intraoperative lead repositioning on septal fibr…
View article: Sudden cardiac death in patients with atrial fibrillation: role of heart failure, coronary artery disease and biomarkers - Insights from the ARISTOTLE trial
Sudden cardiac death in patients with atrial fibrillation: role of heart failure, coronary artery disease and biomarkers - Insights from the ARISTOTLE trial Open
Background Atrial fibrillation (AF) has been suggested as a risk factor for ventricular arrhythmias and sudden cardiac death (SCD). Both heart failure (HF) and coronary artery disease (CAD) are common comorbidities in AF and may influence …
View article: Same‐Day Discharge After Catheter Ablation of Atrial Fibrillation in the United States
Same‐Day Discharge After Catheter Ablation of Atrial Fibrillation in the United States Open
Background Patients undergoing atrial fibrillation (AF) ablation have historically been hospitalized overnight or longer postprocedure. National rates of same‐day discharge (SDD) following AF ablation remain unknown. Methods and Results Th…
View article: Evolving Indications, Challenges and Advances in Cardiac Resynchronization Therapy for Heart Failure
Evolving Indications, Challenges and Advances in Cardiac Resynchronization Therapy for Heart Failure Open
Cardiac resynchronization therapy (CRT) via biventricular pacing has markedly improved heart failure outcomes over the past 2 decades. However, some patients show no clinical improvement or evidence of reverse remodeling following device i…
View article: Patient Preferences for Features Associated With Leadless Versus Conventional Transvenous Cardiac Pacemakers
Patient Preferences for Features Associated With Leadless Versus Conventional Transvenous Cardiac Pacemakers Open
BACKGROUND: Regulatory approval of the first dual-chamber leadless pacemaker system provides patients an alternative to conventional transvenous pacemakers. The study objective was to quantify the preferences of patients for pacemaker feat…
View article: State of the art of mobile health technologies use in clinical arrhythmia care
State of the art of mobile health technologies use in clinical arrhythmia care Open
The rapid growth in consumer-facing mobile and sensor technologies has created tremendous opportunities for patient-driven personalized health management. The diagnosis and management of cardiac arrhythmias are particularly well suited to …
View article: Outcomes of Cardiac Resynchronization Therapy by New York Heart Association Class: A Patient‐Level Meta‐Analysis
Outcomes of Cardiac Resynchronization Therapy by New York Heart Association Class: A Patient‐Level Meta‐Analysis Open
Background Data on the benefits of cardiac resynchronization therapy (CRT) in patients with severe heart failure symptoms are limited. We investigated the relative effects of CRT in patients with ambulatory New York Heart Association (NYHA…
View article: Patient preferences for features associated with leadless versus conventional transvenous cardiac pacemakers
Patient preferences for features associated with leadless versus conventional transvenous cardiac pacemakers Open
Background Regulatory approval of the first dual-chamber leadless pacemaker (PM) system provides patients an alternative to conventional transvenous pacemakers. Objective To quantify patients’ preferences for pacemaker features. Methods Pa…
View article: Association of leadless pacing with ventricular and valvular function
Association of leadless pacing with ventricular and valvular function Open
Background Traditional transvenous pacemakers are associated with worsening tricuspid valve function due to lead‐related leaflet impingement, as well as ventricular dysfunction related to electromechanical dyssynchrony from chronic right v…
View article: Comorbidities and clinical response to cardiac resynchronization therapy: Patient‐level meta‐analysis from eight clinical trials
Comorbidities and clinical response to cardiac resynchronization therapy: Patient‐level meta‐analysis from eight clinical trials Open
Aims Patients with heart failure usually have several other medical conditions that might alter the effects of interventions. We investigated whether the burden of comorbidity modified the clinical response to cardiac resynchronization the…
View article: Utilization and Outcomes of Primary Prevention Implantable Cardioverter‐Defibrillators in Patients With Hypertrophic Cardiomyopathy
Utilization and Outcomes of Primary Prevention Implantable Cardioverter‐Defibrillators in Patients With Hypertrophic Cardiomyopathy Open
Background There is uncertainty about the appropriate use of primary prevention implantable cardioverter‐defibrillators (ICDs) among older patients with hypertrophic cardiomyopathy. Methods and Results Patients with hypertrophic cardiomyop…
View article: Cardiac resynchronization therapy in patients with a prior history of atrial fibrillation: Insights from four major clinical trials
Cardiac resynchronization therapy in patients with a prior history of atrial fibrillation: Insights from four major clinical trials Open
Aims To investigate the association of cardiac resynchronization therapy (CRT) on outcomes among participants with and without a history of atrial fibrillation (AF). Methods Individual‐patient‐data from four randomized trials investigating…
View article: Outcomes of Cardiac Resynchronization Therapy by New York Heart Association Class: A Patient-Level Meta-Analysis
Outcomes of Cardiac Resynchronization Therapy by New York Heart Association Class: A Patient-Level Meta-Analysis Open
Data on the benefits of cardiac resynchronization therapy (CRT) in patients with severe heart failure (HF) symptoms are limited. We investigated the relative effects of CRT in patients with ambulatory NYHA IV vs. III functional class at th…
View article: 2023 <scp>HRS</scp>/<scp>APHRS</scp>/<scp>LAHRS</scp> guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure
2023 <span>HRS</span>/<span>APHRS</span>/<span>LAHRS</span> guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure Open
Cardiac physiologic pacing (CPP), encompassing cardiac resynchronization therapy (CRT) and conduction system pacing (CSP), has emerged as a pacing therapy strategy that may mitigate or prevent the development of heart failure (HF) in patie…
View article: 2023 HRS/APHRS/LAHRS guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure
2023 HRS/APHRS/LAHRS guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure Open
Cardiac physiologic pacing (CPP), encompassing cardiac resynchronization therapy (CRT) and conduction system pacing (CSP), has emerged as a pacing therapy strategy that may mitigate or prevent the development of heart failure (HF) in patie…