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View article: Prednisolone is associated with a worse bone mineral density in primary adrenal insufficiency
Prednisolone is associated with a worse bone mineral density in primary adrenal insufficiency Open
Context Patients with primary adrenal insufficiency (PAI) or congenital adrenal hyperplasia (CAH) receive life-long glucocorticoid (GC) therapy. Daily GC doses are often above the physiological cortisol production rate and can cause long-t…
View article: BclI polymorphism of the glucocorticoid receptor and adrenal crisis in primary adrenal insufficiency
BclI polymorphism of the glucocorticoid receptor and adrenal crisis in primary adrenal insufficiency Open
Context Patients with primary adrenal insufficiency (PAI) or congenital adrenal hyperplasia (CAH) are at a high risk of adrenal crisis (AC). Glucocorticoid sensitivity is at least partially genetically determined by polymorphisms of the gl…
View article: Reduction in daily hydrocortisone dose improves bone health in primary adrenal insufficiency
Reduction in daily hydrocortisone dose improves bone health in primary adrenal insufficiency Open
Objective Individuals with primary adrenal insufficiency (PAI) or congenital adrenal hyperplasia (CAH) receive life-long glucocorticoid (GC) replacement therapy. Current daily GC doses are still higher than the reported adrenal cortisol pr…