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View article: Transposon targeting non-coding RNA transcription targets G/C-rich tracts and is facilitated by an intrinsically disordered protein in <i>Tetrahymena</i>
Transposon targeting non-coding RNA transcription targets G/C-rich tracts and is facilitated by an intrinsically disordered protein in <i>Tetrahymena</i> Open
Tetrahymena is a well-established ciliate model organism, known for its nuclear dualism and unique mechanism for transposon defense, wherein transposons are kept within the highly heterochromatinized micronucleus (MIC), which is transcript…
View article: Who Tells the Story of the Treatment of Androgenetic Alopecia?—A Bibliometric Analysis From 2003 to 2023
Who Tells the Story of the Treatment of Androgenetic Alopecia?—A Bibliometric Analysis From 2003 to 2023 Open
Background Androgenetic alopecia (AGA) is a common form of nonscarring hair loss that affects both men and women, significantly influencing psychological well‐being and quality of life. Although AGA accounts for over 90% of male hair loss,…
View article: Elevational adaptation and distribution of woody saplings in a mountain forest: Insights from functional traits and mycorrhizal associations
Elevational adaptation and distribution of woody saplings in a mountain forest: Insights from functional traits and mycorrhizal associations Open
A trait-based approach can be used to effectively elucidate the adaptive strategies of trees in response to climate change, although the strategies of saplings remain unclear. Therefore, the adaptative strategies of saplings and the relati…
View article: A specialized TFIIB is required for transcription of transposon-targeting noncoding RNAs
A specialized TFIIB is required for transcription of transposon-targeting noncoding RNAs Open
Transposable elements (TEs) pose threats to genome stability. Therefore, small RNA-mediated heterochromatinization suppresses the transcription and hence the mobility of TEs. Paradoxically, transcription of noncoding RNA (ncRNA) from TEs i…
View article: WITHDRAWN: Identification of SUMOylation biomarkers in glioblastoma based on transcriptome and Mendelian randomization combined with single-cell RNA-seq analysis
WITHDRAWN: Identification of SUMOylation biomarkers in glioblastoma based on transcriptome and Mendelian randomization combined with single-cell RNA-seq analysis Open
The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
View article: Multiple types of cutaneous malignant tumors: A case report
Multiple types of cutaneous malignant tumors: A case report Open
Cutaneous malignant tumors are common, prevalent malignancies with high and rising incidence rates. Less attention has been paid to cutaneous malignant tumors because of their wide range of sites, variety of clinical manifestations, and lo…
View article: WITHDRAWN: Identification of SUMOylation biomarkers in glioblastoma based on transcriptome and Mendelian randomization combined with single-cell RNA-seq analysis
WITHDRAWN: Identification of SUMOylation biomarkers in glioblastoma based on transcriptome and Mendelian randomization combined with single-cell RNA-seq analysis Open
Aberrant SUMOylation has been associated with cancer, neurodegenerative diseases, and infections, but its exact role in glioblastoma (GBM) remains unknown. This study aimed to uncover this link and identify novel biomarkers for GBM treatme…
View article: The impact of moral judgment on bystanders’ interpersonal trust: the mediating role of trustworthiness
The impact of moral judgment on bystanders’ interpersonal trust: the mediating role of trustworthiness Open
Interpersonal trust is the premise and foundation of encouraging cooperation in this age of rapid progress. The purpose of this study was to investigate how moral judgment affects bystanders’ interpersonal trust and its internal mechanisms…
View article: IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. tuberculosis in macrophages
IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. tuberculosis in macrophages Open
Cytokine of interferon-gamma (IFNγ) plays a vital role in the immune response against Mycobacteria tuberculosis (Mtb) infection, yet the specific function of T cells producing IFNγ in this process remains unclear. In this study, we first i…
View article: Sea surface barometry with an O2 differential absorption radar: retrieval algorithm development and simulation
Sea surface barometry with an O2 differential absorption radar: retrieval algorithm development and simulation Open
Sea surface air pressure observations are a significant gap in the current Earth observing systems. This study addresses retrieval algorithm development and the evaluation of the potential impact of instrumental and environmental uncertain…
View article: Global sea surface air pressure observations with V-band&#160;O2 differential absorption radar
Global sea surface air pressure observations with V-band O2 differential absorption radar Open
Observed meteorological data are essential for initialization, adjustment, assimilation, and prediction of numerical weather prediction (NWP) models and influence daily activities of people and society. Many key weather variables such as t…
View article: Exploration of the causative gene in a case of multiple nevoid basal cell carcinoma: A case report
Exploration of the causative gene in a case of multiple nevoid basal cell carcinoma: A case report Open
Nevoid basal cell carcinoma syndrome is a rare autosomal dominant disorder characterized by a diverse clinical presentation, which includes developmental abnormalities and tumorigenesis that can impact multiple organ systems. Basal cell ca…
View article: Research on the Deep Integration of Intelligent Speech Recognition Technology and Flipped Classroom for College English Teaching
Research on the Deep Integration of Intelligent Speech Recognition Technology and Flipped Classroom for College English Teaching Open
Currently, intelligent speech recognition technology has become an important tool to improve the quality of English teaching, and the flipped classroom combined with intelligent speech recognition technology not only optimizes the teaching…
View article: Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival
Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival Open
Mycobacterium tuberculosis (Mtb) triggers distinct changes in macrophages, resulting in the formation of lipid droplets that serve as a nutrient source. We discover that Mtb promotes lipid droplets by inhibiting DNA repair responses, resul…
View article: Multifaceted roles of T cells in obesity and obesity‐related complications: A narrative review
Multifaceted roles of T cells in obesity and obesity‐related complications: A narrative review Open
Summary Obesity is characterized by chronic low‐grade inflammatory responses in the adipose tissue, accompanied by pronounced insulin resistance and metabolic anomalies. It affects almost all body organs and eventually leads to diseases su…
View article: Nitrogen and Phosphorus Co-Doped Carbon Dots for the Growth Promotion of Water Spinach
Nitrogen and Phosphorus Co-Doped Carbon Dots for the Growth Promotion of Water Spinach Open
Carbon dots have received much attention due to their unique physicochemical properties and diverse applications in bioimaging, optoelectronic devices, catalysis, and agriculture. Here, in this work, we report a simple hydrothermal synthes…
View article: Nitrogen and Phosphorus Co-Doped Carbon Dots for the Growth Promotion of Water Spinach
Nitrogen and Phosphorus Co-Doped Carbon Dots for the Growth Promotion of Water Spinach Open
Carbon dots have received much attention due to their unique physicochemical properties and diverse applications in bioimaging, optoelectronic devices, catalysis, and agriculture. Here in this work, we report a simple hydrothermal synthesi…
View article: Simulations of sea surface reflection for V-band O2 differential absorption radar barometry
Simulations of sea surface reflection for V-band O2 differential absorption radar barometry Open
This study simulates V-band sea surface reflectance and normalized radar cross-section (NRCS) for sea surface air pressure barometry using a differential absorption radar operating at three spectrally even spaced close frequency bands (65.…
View article: Comparative Physiological Analysis of Lignification, Anthocyanin Metabolism and Correlated Gene Expression in Red Toona sinensis Buds during Cold Storage
Comparative Physiological Analysis of Lignification, Anthocyanin Metabolism and Correlated Gene Expression in Red Toona sinensis Buds during Cold Storage Open
The characteristics of anthocyanin and lignin are important parameters in evaluating the quality of red Toona sinensis buds. Red T. sinensis buds are prone to senescence during postharvest storage, which subsequently affects their quality …
View article: The machine learning model based on trajectory analysis of ribonucleic acid test results predicts the necessity of quarantine in recurrently positive patients with SARS-CoV-2 infection
The machine learning model based on trajectory analysis of ribonucleic acid test results predicts the necessity of quarantine in recurrently positive patients with SARS-CoV-2 infection Open
Background SARS-CoV-2 patients re-experiencing positive nucleic acid test results after recovery is a concerning phenomenon. Current pandemic prevention strategy demands the quarantine of all recurrently positive patients. This study provi…
View article: Advances in T Cells Based on Inflammation in Metabolic Diseases
Advances in T Cells Based on Inflammation in Metabolic Diseases Open
With the increasing incidence of metabolic diseases year by year and their impact on the incidence of cardiovascular diseases, metabolic diseases have attracted great attention as a major health care problem, but there is still no effectiv…
View article: VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway
VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway Open
Diabetic retinopathy (DR) is a common microvascular complication in patients with diabetes mellitus. DR is caused by chronic hyperglycemia and is characterized by progressive loss of vision because of damage to the retinal microvasculature…
View article: MicroRNAs in Kawasaki disease: An update on diagnosis, therapy and monitoring
MicroRNAs in Kawasaki disease: An update on diagnosis, therapy and monitoring Open
Kawasaki disease (KD) is an acute autoimmune vascular disease featured with a long stage of febrile. It predominantly afflicts children under 5 years old and causes an increased risk of cardiovascular combinations. The onset and progressio…
View article: Status and strategies of college English teaching using adaptive deep learning from the perspective of multiculturalism
Status and strategies of college English teaching using adaptive deep learning from the perspective of multiculturalism Open
The aim is to deeply understand the current situation of College English Teaching (CET). By consulting the theories of Deep Learning (DL) and Edge Computing (EC), this work designs a Questionnaire Survey (QS) to understand the current situ…
View article: MoO3 Nanobelt-Modified HMCM-49 Zeolite with Enhanced Dispersion of Mo Species and Catalytic Performance for Methane Dehydro-Aromatization
MoO3 Nanobelt-Modified HMCM-49 Zeolite with Enhanced Dispersion of Mo Species and Catalytic Performance for Methane Dehydro-Aromatization Open
The methane dehydro-aromatization reaction (MDA) is a promising methane valorization process due to the conversion of methane to value-added aromatics (benzene, toluene and naphthalene). However, one of the major disadvantages of utilizing…
View article: The Bus Control System Based on Intelligent Security Design
The Bus Control System Based on Intelligent Security Design Open
Due to traffic congestion and the changeable internal and external driving environment, it is difficult for bus drivers to respond quickly to the surrounding environment in an emergency, resulting in traffic accidents. This paper designs a…
View article: Study on quasi two-stage compression cycle characteristics of the water heater of the air source heat pump in cold area
Study on quasi two-stage compression cycle characteristics of the water heater of the air source heat pump in cold area Open
The water heater of an air source heat pump has the disadvantages of high exhaust temperature and weak heating performance in a cold area. The quasi two-stage compression cycle technology can effectively improve its operation characteristi…