Lan Ma
YOU?
Author Swipe
View article: Application of the BOPPPS combined with CBL method in clinical clerkship of pediatric dentistry
Application of the BOPPPS combined with CBL method in clinical clerkship of pediatric dentistry Open
The combination of the BOPPPS model with CBL enhances students' master of knowledge, promotes active learning, and elevates the quality of clinical clerkship education in pediatric dentistry. This innovative method has been proved as an ef…
View article: GWAS Identified Loci Associated With Orthodontically EARR Of Maxillary Incisors
GWAS Identified Loci Associated With Orthodontically EARR Of Maxillary Incisors Open
Aim or purpose: To identify the genetic susceptibility factors of orthodontic induced external apical root resorption (EARR) of maxillary incisors. Materials and methods: The study was approved by the institutional ethics committee of the …
View article: Dysbiotic Gut Microbiota Correlates with Altered Serum and Urinary Biomarkers in Recurrent Calcium Oxalate Stone Patients
Dysbiotic Gut Microbiota Correlates with Altered Serum and Urinary Biomarkers in Recurrent Calcium Oxalate Stone Patients Open
Gut microbiota dysbiosis correlates with metabolic and urinary abnormalities in recurrent stone formers. Monitoring E. coli levels and biochemical parameters may aid recurrence prediction.
View article: Disturbed engram network caused by NPTX downregulation underlies aging-related contextual fear memory deficits
Disturbed engram network caused by NPTX downregulation underlies aging-related contextual fear memory deficits Open
Engram cells storing episodic memories are allocated to separate neuronal ensembles. However, how these ensembles maintain their stability to drive precise memory expression, and whether their destabilization contributes to aging-related m…
View article: Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress
Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress Open
Acute stressors, significant risk factors for mood disorders, increase anxiety and reduce reward sensitivity. However, the underlying neuroadaptive mechanisms remain unclear. Here, it is shown that acute restraint stress upregulates Signal…
View article: Lyophilized apoptotic vesicles restore DNA damage and mitochondria dysfunction to ameliorate radiation enteritis
Lyophilized apoptotic vesicles restore DNA damage and mitochondria dysfunction to ameliorate radiation enteritis Open
Radiation therapy for malignant tumor patients often induces radiation enteritis (RE), a condition that impairs their quality of life. Currently, there is no standard treatment regimen available. In this study, we used lyophilized apoptoti…
View article: The intrinsic excitability of and autophagy protein expression levels in dentate gyrus ensembles regulate fear generalization
The intrinsic excitability of and autophagy protein expression levels in dentate gyrus ensembles regulate fear generalization Open
The overgeneralization of fear is associated with psychiatric disorders and cognitive decline. Recent studies have shown that engram cells in the dorsal dentate gyrus are integrated into functionally heterogeneous ensembles that are involv…
View article: Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Improve 5-FU-Induced Delayed Wound Healing by Mitochondrial Transfer
Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Improve 5-FU-Induced Delayed Wound Healing by Mitochondrial Transfer Open
Background/Objectives: This study aimed to explore the therapeutic potential of umbilical mesenchymal stem cell-derived apoptotic vesicles (UMSC-apoVs) in a 5-Fluorouracil (5-FU)-induced impairment in skin wound healing. Methods: UMSC-apoV…
View article: A Study on the Influence of Borrowing on Household Consumption Expenditures: A Layered Comparison from the Perspective of Alleviating Relative Poverty
A Study on the Influence of Borrowing on Household Consumption Expenditures: A Layered Comparison from the Perspective of Alleviating Relative Poverty Open
This study investigates how borrowing influences household consumption patterns in low-income and formerly impoverished regions of China, with implications for sustainable development goals (SDGs) such as poverty reduction (SDG 1), inclusi…
View article: Paternal heroin self-administration in rats increases drug-seeking behavior in male offspring via miR-19b downregulation in the nucleus accumbens
Paternal heroin self-administration in rats increases drug-seeking behavior in male offspring via miR-19b downregulation in the nucleus accumbens Open
Accumulating evidence indicates that drug addiction may lead to adaptive behavioral changes in offspring, potentially due to epigenetic modifications in parental germline. However, the underlying mechanisms remain inadequately understood. …
View article: Machine learning approaches for predicting fetal macrosomia at different stages of pregnancy: a retrospective study in China
Machine learning approaches for predicting fetal macrosomia at different stages of pregnancy: a retrospective study in China Open
This is the first study to utilize machine learning with data from the pre-pregnancy, first-trimester, and pre-labor periods to predict macrosomia. The logistic regression model and the final ensemble model demonstrated strong predictive p…
View article: Corrigendum: A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection
Corrigendum: A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection Open
[This corrects the article DOI: 10.3389/fimmu.2024.1530364.].
View article: A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection
A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection Open
Background Epstein–Barr virus (EBV) is a significant global public health concern because of its association with various malignancies and autoimmune diseases. Over 90% of the global population is chronically infected with EBV, impacting n…
View article: The Efficacy and Safety of Selinexor in Combination with Ruxolitinib in Ruxolitinib-Treated Myelofibrosis Patients: The Interim Analysis of a Prospective, Open-Label, Multicenter, Parallel-Cohort, Phase 2 Study
The Efficacy and Safety of Selinexor in Combination with Ruxolitinib in Ruxolitinib-Treated Myelofibrosis Patients: The Interim Analysis of a Prospective, Open-Label, Multicenter, Parallel-Cohort, Phase 2 Study Open
Background: Myelofibrosis is a chronic hematologic malignancy characterized by constitutional symptoms, bone marrow fibrosis, extramedullary hematopoiesis resulting in splenomegaly and a propensity toward leukemic progression. Although JAK…
View article: Prognostic Significance of POD24 and Monoclonal Paraproteinemia in Extranodal MZL
Prognostic Significance of POD24 and Monoclonal Paraproteinemia in Extranodal MZL Open
Marginal zone lymphoma (MZL) is a relatively uncommon subtype of non-Hodgkin's lymphoma, which can be categorized into three types: splenic MZL, nodal MZL (NMZL), and extranodal MZL (EMZL) of mucosa-associated lymphoid tissue (MALT). Extra…
View article: Precise hourly personalized embryo transfer significantly improves clinical outcomes in patients with repeated implantation failure
Precise hourly personalized embryo transfer significantly improves clinical outcomes in patients with repeated implantation failure Open
Purpose This study investigated whether RNA-Seq-based endometrial receptivity test (rsERT)—which provides precision for the optimal hour of the window of implantation (WOI)—can improve clinical outcomes of frozen embryo transfer (FET) cycl…
View article: Paternal Preconception Donepezil Exposure Enhances Learning in Offspring
Paternal Preconception Donepezil Exposure Enhances Learning in Offspring Open
Background Recent research has indicated that parental use of central nervous system-targeting medications during periconceptional periods may affect offspring across various developmental and behavioral domains. The present study sought t…
View article: Carvedilol to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension stratified by liver stiffness: study protocol for a randomied, double-blind, placebo-controlled, multicentre trial in China
Carvedilol to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension stratified by liver stiffness: study protocol for a randomied, double-blind, placebo-controlled, multicentre trial in China Open
Introduction Patients with clinically significant portal hypertension (CSPH) are recommended to be treated with non-selective beta-blockers (ie, carvedilol) to prevent the first hepatic decompensation event by the renewing Baveno VII conse…
View article: The notable outcomes of modified thiotepa-based conditioning followed by autologous stem cell transplantation in primary central nervous system lymphomas: A real-life pilot study
The notable outcomes of modified thiotepa-based conditioning followed by autologous stem cell transplantation in primary central nervous system lymphomas: A real-life pilot study Open
High-dose chemotherapy followed by autologous stem cell transplantation (HDC–ASCT) is a promising approach for patients with primary central nervous system lymphoma (PCNSL). Encouraging results have been reported with thiotepa-based condit…
View article: Destabilization of fear memory by Rac1-driven engram-microglia communication in hippocampus
Destabilization of fear memory by Rac1-driven engram-microglia communication in hippocampus Open
Rac1 is a key regulator of the cytoskeleton and neuronal plasticity, and is known to play a critical role in psychological and cognitive brain disorders. To elucidate the engram specific Rac1 signaling in fear memory, a doxycycline (Dox)-d…
View article: Effects of bone marrow sparing radiotherapy on acute hematologic toxicity for patients with locoregionally advanced cervical cancer: a prospective phase II randomized controlled study
Effects of bone marrow sparing radiotherapy on acute hematologic toxicity for patients with locoregionally advanced cervical cancer: a prospective phase II randomized controlled study Open
Objective To evaluate effects of bone marrow sparing (BMS) radiotherapy on decreasing the incidence of acute hematologic toxicity (HT) for locoregionally advanced cervical cancer (LACC) patients treated by pelvic irradiation. Materials and…
View article: Apoptotic vesicles are required to repair DNA damage and suppress premature cellular senescence
Apoptotic vesicles are required to repair DNA damage and suppress premature cellular senescence Open
It is well known that DNA damage can cause apoptosis. However, whether apoptosis and its metabolites contribute to DNA repair is largely unknown. In this study, we found that apoptosis‐deficient Fas mut and Bim − /− mice show significantly…