Explanipedia

The Nationwide Impact of COVID‐19 on Lung Donation and Transplantation in Belgium Open

Jan Van Slambrouck, Robin Vos, Isabelle Étienne, François Carlier, Veronique Verplancke , et al. · 2025

SARS‐CoV‐2 primarily infects the respiratory tract. Consequently, lung transplantation (LTx) programs have been significantly impacted by the COVID‐19 pandemic. This study aimed to summarize the impact of the pandemic on LTx in Belgium. Eu…

Disparities in donor heart acceptance between the USA and Europe: clinical implications Open

Brian Wayda, Philipp Angleitner, Jacqueline M. Smits, Arne van Kins, Michael Berchtold‐Herz , et al. · 2023

Background and Aims Given limited evidence and lack of consensus on donor acceptance for heart transplant (HT), selection practices vary widely across HT centres in the USA. Similar variation likely exists on a broader scale—across countri…

Outcomes in patients with cardiac amyloidosis undergoing heart transplantation: the eurotransplant experience Open

Martin J. Kraus, Jacqueline M. Smits, Anna L. Meyer, Agita Strēlniece, Arne van Kins , et al. · 2023

Impact of diastolic pulmonary gradient and pulmonary artery pulse index on outcomes in heart transplant patients—Results from the Eurotransplant database Open

Tobias Wagner, Christina Magnussen, A. Bernhardt, Jacqueline M. Smits, Katrin Steinbach , et al. · 2022

Background Predicting complications associated with pulmonary hypertension (PH) after cardiac transplantation is an important factor when considering cardiac transplantation. The transpulmonary gradient (TPG) is recommended to quantify PH …

Gamma-glutamyltransferase is a strong predictor of secondary sclerosing cholangitis after lung transplantation for COVID-19 ARDS Open

Stefan Schwarz, Christian Lang, Matevž Harlander, Tomaž Štupnik, Jan Van Slambrouck , et al. · 2022

SSC-CIP is a severe late complication after LTx for COVID-19 ARDS leading to significant morbidity and mortality. GGT appears to be a sensitive parameter able to predict SSC-CIP even at the time of listing.

Psychosocial Risk and Health Behaviors as Predictors of Clinical Events in Patients Wait-Listed for a New Heart: Results from 7 Years of Follow-Up Open

Kathleen Gali, Gerdi Weidner, Jacqueline M. Smits, Jan Beyersmann, Heike Spaderna · 2021

We examined the long-term relationship of psychosocial risk and health behaviors on clinical events in patients awaiting heart transplantation (HTx). Psychosocial characteristics (e.g., depression), health behaviors (e.g., dietary habits, …

Study design and rationale of the pAtients pResenTing with cOngenital heaRt dIseAse Register (ARTORIA‐R) Open

Christoph Sinning, Elvin Zengin, Gerhard‐Paul Diller, Francesco Onorati, M. Castel , et al. · 2021

Aim Due to improved therapy in childhood, many patients with congenital heart disease reach adulthood and are termed adults with congenital heart disease (ACHD). ACHD often develop heart failure (HF) as a consequence of initial palliative …

Requests for Exceptional LAS in Eurotransplant Open

Robin Vos, Jacqueline M. Smits, Agita Strēlniece, Rikke Buhl, T. Deuse , et al. · 2021

The adapted Heart Donor Score Open

Philipp Angleitner, Alexandra Kaider, Jacqueline M. Smits, A. Aliabadi-Zuckermann, Emilio Osorio‐Jaramillo , et al. · 2021

The Heart Donor Score (HDS) predicts donor organ discard for medical reasons and survival after heart transplantation (HTX) in the Eurotransplant allocation system. Our aim was to adapt the HDS for application in the United Network for Org…

Clinical characteristics and outcomes of patients with adult congenital heart disease listed for heart and heart‒lung transplantation in the Eurotransplant region Open

Peter Moritz Becher, Benedikt Schrage, Jessica Weimann, Jacqueline M. Smits, Christina Magnussen , et al. · 2020

New French heart allocation system: Comparison with Eurotransplant and US allocation systems Open

Richard Dorent, Carine Jasseron, Benoît Audry, Florian Bayer, Camille Legeai , et al. · 2020

Impact of donor lung quality on post‐transplant recipient outcome in the Lung Allocation Score era in Eurotransplant – a historical prospective study Open

Jacqueline M. Smits, Jens Gottlieb, Erik A.M. Verschuuren, Patrick Evrard, Rogier A.S. Hoek , et al. · 2020

The aim of this study was to investigate whether there is an impact of donation rates on the quality of lungs used for transplantation and whether donor lung quality affects post-transplant outcome in the current Lung Allocation Score era.…

Heart re-transplantation in Eurotransplant Open

Jacqueline M. Smits, Michel De Pauw, Uwe Schulz, Johan Van Cleemput, Philip Raake , et al. · 2018

Internationally 3% of the donor hearts are distributed to re-transplant patients. In Eurotransplant, only patients with a primary graft dysfunction (PGD) within 1 week after heart transplantation (HTX) are indicated for high urgency listin…

Lung allocation score: the Eurotransplant model versus the revised US model - a cross-sectional study Open

Jacqueline M. Smits, George Nossent, Patrick Evrard, György Láng, Christiane Knoop , et al. · 2018

Both Eurotransplant (ET) and the US use the lung allocation score (LAS) to allocate donor lungs. In 2015, the US implemented a new algorithm for calculating the score while ET has fine-tuned the original model using business rules. A compa…

Lung transplantation after allogeneic stem cell transplantation: a pan-European experience Open

Mark Greer, Cristina Berastegui, Péter Jaksch, Christian Benden, John‐David Aubert , et al. · 2018

Late-onset noninfectious pulmonary complications (LONIPCs) affect 6% of allogeneic stem cell transplantation (SCT) recipients within 5 years, conferring subsequent 5-year survival of 50%. Lung transplantation is rarely performed in this se…

Role of Depression and Social Isolation at Time of Waitlisting for Survival 8 Years After Heart Transplantation Open

Heike Spaderna, Armin Zittermann, Hermann Reichenspurner, Corinna Ziegler, Jacqueline M. Smits , et al. · 2017

Background We evaluated depression and social isolation assessed at time of waitlisting as predictors of survival in heart transplant ( HT x) recipients. Methods and Results Between 2005 and 2006, 318 adult HT x candidates were enrolled in…

In Reply Open

Jens Gottlieb, Jacqueline M. Smits · 2017

Unlocking the Potential of Organ Donation Open

Jacqueline M. Smits · 2017

A retrospective database analysis to evaluate the potential of ex vivo lung perfusion to recruit declined lung donors Open

A Martens, Dirk Van Raemdonck, Jacqueline M. Smits, Stijn E. Verleden, Robin Vos , et al. · 2017

Ex vivo lung perfusion (EVLP) is currently used for both standard and extended-criteria donor (ECD) lungs. To enlarge the donor pool, we might have to extend the threshold for ECD donation. The purpose of this study was to estimate how man…

Lung Transplantation in Germany Since the Introduction of the Lung Allocation Score Open

Jens Gottlieb, Jacqueline M. Smits, René Schramm, Frank Langer, Roland Buhl , et al. · 2017

The introduction of the LAS in Germany was associated with a decrease in the number of patients on the waiting list, and also in the number of deaths among patients on the waiting list. The distribution of primary diagnoses among transplan…

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