Explanipedia

Exploring viral diversity in diarrheic porcine feces: a metagenomic analysis from an Indian swine farm Open

Sushila Maan, Kanisht Batra, Jeyaprakash Rajendhran, R. Joseph, Vikash Singh , et al. · 2025

Background Pig husbandry is a vital sector in India, providing nutritional security and employment for marginalized communities. Pigs are advantageous due to high reproduction rates and fecundity, shorter generation intervals, and efficien…

A new mathematical model approach on the oncolytic virotherapy potency Open

A‎. ‎T‎. Alshammari, Narender S. Maan, Mahmoud A. M. Abdelaziz · 2024

In recent times, there has been an increasing focus on investigating the therapeutic capacity of virus particles in the management of cancer.This paper introduces a novel discrete-time mathematical model with fractional-order of oncolytic …

Development of a multiplexed Luminex assay for simultaneous detection of enteric viruses in cattle. Open

Monika Punia, Sushila Maan, Kanisht Batra, Aman Kumar, Narender S. Maan , et al. · 2024

Viral and bacterial gastroenteritis and diarrhea have long been a problem in livestock with devastating effects on animal health and production causing a heavy financial burden on producers. Therefore, the bead-based multiplex detection as…

Co-infection of bluetongue virus serotypes 12 and 16 in sheep from Haryana, India. Open

Anita Dalal, N. K. Kakker, Deepika Chaudhary, Aman Kumar, Narender S. Maan , et al. · 2023

World Organization for Animal Health has listed bluetongue (BT) under notifiable diseases. The BT is an arboviral infectious disease of domestic and wild ruminants caused by the bluetongue virus (BTV). Southern states of India had remained…

Do small RNAs have potential in disease diagnosis and treatment? Open

Sushila Maan, Kanisht Batra, Narender S. Maan · 2021

Ribonucleic acids (RNAs) are very complex and their complete functions are yet to be fully elucidated. Noncoding RNAs having no protein-coding capacity are represented by housekeeping noncoding RNA...

VP2 Gene-Based Molecular Evolutionary Patterns of Major Circulating Bluetongue Virus Serotypes Isolated during 2014–2018 from Telangana and Andhra Pradesh States of India Open

Thota Ravali, Vishweshwar Kumar Ganji, Sharanya Machanagari, Narasimha Reddy Yella, Bhagyalakshmi Buddala , et al. · 2020

Introduction: Bluetongue disease is an economically important viral disease of livestock caused by bluetongue virus (BTV) having multiple serotypes. It belongs to the genus Orbivirus of family Reoviridae and subfamily …

Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation Open

M. Saminathan, Karam Pal Singh, S. Vineetha, Madhulina Maity, Sanchay Kumar Biswas , et al. · 2020

Transplacental transmission (TPT) of wild-type Indian BTV-1 had never been experimentally proved. This study was first time investigated TPT of Indian BTV-1 (isolated from aborted and stillborn goat fetal spleens). The sequential pathology…

Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot Open

Maude Jacquot, P P Rao, Sarita Yadav, Kyriaki Nomikou, Sushila Maan , et al. · 2019

For segmented viruses, rapid genomic and phenotypic changes can occur through the process of reassortment, whereby co-infecting strains exchange entire segments creating novel progeny virus genotypes. However, for many viruses with segment…

Development of Next Generation Sequencing Protocols for dsRNA Viruses Open

Sushila Maan, Deepika Chaudhary, Nitish Bansal, Bhanita Devi, Narender S. Maan · 2019

Next generations sequencing (NGS) is a very important tool to identify pathogens in different forms i.e. viruses, bacteria etc. This helpful in decode life mysteries, detect pathogens and improve life qualities. Next generation sequencing/…

Quantitative RT-PCR assays for identification and typing of the Equine encephalosis virus Open

Sushila Maan, Manjunatha N. Belaganahalli, Narender S. Maan, A. C. Potgieter, Peter Mertens · 2018

Comparative Neuropathology of Major Indian Bluetongue Virus Serotypes in a Neonatal BALB/c Mouse Model Open

A. Anjaneya, Karam Pal Singh, Susan Cherian, M. Saminathan, Rajendra Singh , et al. · 2018

Novel Molecular Diagnostics and Therapeutic Tools for Livestock Diseases Open

Sushila Maan, Sangeeta Dalal, Aman Kumar, Anita Dalal, Nitish Bansal , et al. · 2018

Whole Genome Sequence Analysis of Bluetongue Virus Serotype 12 from Northern India Open

Anita Dalal, N. K. Kakker, Aman Kumar, Deepika Chaudhary, Nitish Bansal , et al. · 2017

All ten genome segments of a field strain (isolate ID: IND2016/118) of Bluetongue virus serotype 12 (BTV-12), isolated from affected sheep from village Pataudi, Gurugram, Haryana, northern India were sequenced. The total genome size was 19…

A comprehensive study on seroprevalence of bluetongue virus in Haryana state of India Open

Sushila Maan, Anuj Tiwari, Deepika Chaudhary, Anita Dalal, Nitish Bansal , et al. · 2017

The study showed that BTV is circulating in cattle and buffalo populations in the Northern part of India.

Isolation and evolutionary analysis of Australasian topotype of bluetongue virus serotype 4 from India Open

Y V Reddy, B. Susmitha, Sapana A. Patil, Y. Krishnajyothi, Kalyani Putty , et al. · 2017

Bluetongue (BT) is a Culicoides-borne disease caused by several serotypes of bluetongue virus (BTV). Similar to other insect-borne viral diseases, distribution of BT is limited to distribution of Culicoides species competent to transmit BT…

Molecular analysis of genome segment-3 of bluetongue virus serotype 12 isolates from Haryana Open

Anita Dalal, Sushila Maan, Nitish Bansal, Vinay Kumar, Aman Kumar , et al. · 2017

The study confirmed the circulation of BTV-12 in Haryana, India. The variations shown in genome Seg-3 of BTV-12 isolates may have some significance and need to be further explored.

Concurrent infection of Bluetongue and Peste-des-petits-ruminants virus in small ruminants in Haryana State of India Open

Sushila Maan, Aman Kumar, Aditya K. Gupta, Anita Dalal, Deepika Chaudhary , et al. · 2017

Bluetongue (BT) and peste-des-petits-ruminants (PPR) are major transboundary diseases of small ruminant, which are endemic in India. Testing of bluetongue virus (BTV) and peste-des-petits-ruminants virus (PPRV) from recent outbreaks (2015-…

Dual Infection with Bluetongue Virus Serotypes and First-Time Isolation of Serotype 5 in India Open

Divakar Hemadri, Sushila Maan, Mohammed Mudassar Chanda, P P Rao, Kalyani Putty , et al. · 2016

Bluetongue is endemic in India and has been reported from most Indian states. Of late, the clinical disease is most frequently seen in the states of Andhra Pradesh, Telangana (erstwhile Andhra Pradesh state), Tamil Nadu and Karnataka. Our …

Development and Evaluation of Real Time RT-PCR Assays for Detection and Typing of Bluetongue Virus Open

Sushila Maan, Narender S. Maan, Manjunatha N. Belaganahalli, A. C. Potgieter, Vinay Kumar , et al. · 2016

Bluetongue virus is the type species of the genus Orbivirus, family Reoviridae. Bluetongue viruses (BTV) are transmitted between their vertebrate hosts primarily by biting midges (Culicoides spp.) in which they also replicate. Consequently…

Development of Real-Time RT-PCR Assays for Detection and Typing of Epizootic Haemorrhagic Disease Virus Open

Narender S. Maan, Sushila Maan, A. C. Potgieter, Isabella Wright, Manjunatha N. Belaganahalli , et al. · 2016

Epizootic haemorrhagic disease virus (EHDV) is an emerging arboviral pathogen of wild and domestic ruminants worldwide. It is closely related to bluetongue virus (BTV) and is transmitted by adult females of competent Culicoides vector spec…

Development and evaluation of loop-mediated isothermal amplification assay for rapid detection of Capripoxvirus Open

Kanisht Batra, Aman Kumar, Vinay Kumar, Trilok Nanda, Narender S. Maan , et al. · 2015

LAMP assay can be a very good alternative for CaPV detection to other molecular techniques requiring sophisticated equipments.

Full-Genome Sequencing as a Basis for Molecular Epidemiology Studies of Bluetongue Virus in India Open

Sushila Maan, Narender S. Maan, Manjunatha N. Belaganahalli, P P Rao, Karam Pal Singh , et al. · 2015

Since 1998 there have been significant changes in the global distribution of bluetongue virus (BTV). Ten previously exotic BTV serotypes have been detected in Europe, causing severe disease outbreaks in naïve ruminant populations. Previous…

Genetic Characterization of the Tick-Borne Orbiviruses Open

Manjunatha N. Belaganahalli, Sushila Maan, Narender S. Maan, Joe Brownlie, Robert B. Tesh , et al. · 2015

The International Committee for Taxonomy of Viruses (ICTV) recognizes four species of tick-borne orbiviruses (TBOs): Chenuda virus, Chobar Gorge virus, Wad Medani virus and Great Island virus (genus Orbivirus, family Reoviridae). Nucleotid…

Genome Sequence of Bluetongue Virus Type 2 from India: Evidence for Reassortment between Outer Capsid Protein Genes Open

Sushila Maan, Narender S. Maan, Manjunatha N. Belaganahalli, Aman Kumar, Kanisht Batra , et al. · 2015

Southern Indian isolate IND1994/01 of bluetongue virus serotype 2 (BTV-2), from the Orbivirus Reference Collection at the Pirbright Institute ( http://www.reoviridae.org/dsRNA_virus_proteins/ReoID/btv-2.htm#IND1994/01 ), was sequenced. Its…

Isolation and Characterization of Mannheimia varigena from a Murrah Buffalo Open

Sarita Yadav, Aman Kumar, Sushila Maan, Ashok Boora, Narender S. Maan , et al. · 2015

The present study was aimed to isolate and characterize phenotypically as well as genotypically bacterial strain from tracheal froth of a Murrah buffalo on the Government livestock farm (GLF) located at Hisar, Haryana. The isolate showed t…

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