Maarit J. Ahava
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View article: What is the proportion of samples reported as positive among reactive samples in Siemens Atellica IM analyzer HIV and HCV serological screening?
What is the proportion of samples reported as positive among reactive samples in Siemens Atellica IM analyzer HIV and HCV serological screening? Open
View article: Impact of selective reporting of wound cultures on microbiology reports and antimicrobial-drug use on a wound-care ward in Finland: a retrospective cohort study
Impact of selective reporting of wound cultures on microbiology reports and antimicrobial-drug use on a wound-care ward in Finland: a retrospective cohort study Open
HUS Diagnostic Center.
View article: Shiga toxin‐producing <i>Escherichia coli</i> (STEC) stool multiplex PCR can replace culture for clinical diagnosis and follow‐up
Shiga toxin‐producing <i>Escherichia coli</i> (STEC) stool multiplex PCR can replace culture for clinical diagnosis and follow‐up Open
Shiga toxin ( stx )‐producing Escherichia coli (STEC) causes potentially severe gastrointestinal infections. Due to its public health importance, control measures are required, and carriers may need to refrain from work or daycare when the…
View article: Low incidence of severe bacterial infections in hospitalised patients with COVID-19: A population-based registry study
Low incidence of severe bacterial infections in hospitalised patients with COVID-19: A population-based registry study Open
Bacterial infections complicating COVID-19 are rare but present a challenging clinical entity. The aim of this study was to evaluate the incidence, aetiology and outcome of severe laboratory-verified bacterial infections in hospitalised pa…
View article: The phylodynamics of SARS-CoV-2 during 2020 in Finland
The phylodynamics of SARS-CoV-2 during 2020 in Finland Open
View article: Rapid increase in SARS-CoV-2 seroprevalence during the emergence of Omicron variant, Finland
Rapid increase in SARS-CoV-2 seroprevalence during the emergence of Omicron variant, Finland Open
View article: Rapid increase in SARS-CoV-2 seroprevalence during the emergence of Omicron variant, Finland
Rapid increase in SARS-CoV-2 seroprevalence during the emergence of Omicron variant, Finland Open
Objectives The aim of this study was to assess changes in exposure and prevalence of SARS-CoV-2 infection during the first months of emergence of Omicron variant in the Greater Helsinki area, Finland. Methods A prospective seroepidemiologi…
View article: Detection of SARS-CoV-2 nucleocapsid antigen from serum can aid in timing of COVID-19 infection
Detection of SARS-CoV-2 nucleocapsid antigen from serum can aid in timing of COVID-19 infection Open
View article: Low incidence of severe bacterial infections in hospitalised patients with COVID-19: A population-based registry study
Low incidence of severe bacterial infections in hospitalised patients with COVID-19: A population-based registry study Open
Bacterial infections complicating COVID-19 are rare but present a challenging clinical entity. The aim of this study was to evaluate the incidence, aetiology and outcome of severe laboratory-verified bacterial infections in hospitalised pa…
View article: The phylodynamics of SARS-CoV-2 during 2020 in Finland — Disappearance and re-emergence of introduced strains.
The phylodynamics of SARS-CoV-2 during 2020 in Finland — Disappearance and re-emergence of introduced strains. Open
View article: Real-life clinical sensitivity of SARS-CoV-2 RT-PCR test in symptomatic patients
Real-life clinical sensitivity of SARS-CoV-2 RT-PCR test in symptomatic patients Open
Background Understanding the false negative rates of SARS-CoV-2 RT-PCR testing is pivotal for the management of the COVID-19 pandemic and it has implications for patient management. Our aim was to determine the real-life clinical sensitivi…
View article: A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept Open
PCR is currently the gold standard for the diagnosis of many acute infections. While PCR and its variants are highly sensitive and specific, the time from sampling to results is measured in hours at best.
View article: Evaluation of three rapid lateral flow antigen detection tests for the diagnosis of SARS-CoV-2 infection
Evaluation of three rapid lateral flow antigen detection tests for the diagnosis of SARS-CoV-2 infection Open
View article: Detection of SARS-CoV-2 nucleocapsid antigen from serum can aid in timing of COVID-19 infection
Detection of SARS-CoV-2 nucleocapsid antigen from serum can aid in timing of COVID-19 infection Open
SARS-CoV-2 RNA can be detected in respiratory samples for weeks or even months after onset of COVID-19 disease. Therefore, one of the diagnostic challenges of PCR positive cases is differentiating between acute COVID-19 disease and convale…
View article: Evaluation of three rapid lateral flow antigen detection tests for the diagnosis of SARS-CoV-2 infection
Evaluation of three rapid lateral flow antigen detection tests for the diagnosis of SARS-CoV-2 infection Open
Introduction The COVID-19 pandemic has led to high demand of diagnostic tools. Rapid antigen detection tests have been developed and many have received regulatory acceptance such as CE IVD or FDA markings. Their performance needs to be car…
View article: Male predominance in disease severity and mortality in a low Covid-19 epidemic and low case-fatality area – a population-based registry study
Male predominance in disease severity and mortality in a low Covid-19 epidemic and low case-fatality area – a population-based registry study Open
Men reportedly suffer from a more severe disease and higher mortality during the global SARS-CoV-2 (Covid-19) pandemic. We analysed sex differences in a low epidemic area with low overall mortality in Covid-19 in a population based setting…
View article: A generic, scalable, and rapid TR-FRET –based assay for SARS-CoV-2 antigen detection
A generic, scalable, and rapid TR-FRET –based assay for SARS-CoV-2 antigen detection Open
The ongoing COVID-19 pandemic has seen an unprecedented increase in the demand for rapid and reliable diagnostic tools, leaving many laboratories scrambling for resources. We present a fast and simple method for the detection of SARS-CoV-2…
View article: Real-life clinical sensitivity of SARS-CoV-2 RT-PCR test in symptomatic patients
Real-life clinical sensitivity of SARS-CoV-2 RT-PCR test in symptomatic patients Open
Importance Understanding the false negative rates of SARS-CoV-2 RT-PCR testing is pivotal for the management of the COVID-19 pandemic and it has practical implications for patient management in healthcare facilities. Objective To determine…
View article: SARS-CoV-2 sample-to-answer nucleic acid testing in a tertiary care emergency department: evaluation and utility
SARS-CoV-2 sample-to-answer nucleic acid testing in a tertiary care emergency department: evaluation and utility Open
View article: SARS-CoV-2 sample-to-answer nucleic acid testing in a tertiary care emergency department: evaluation and utility
SARS-CoV-2 sample-to-answer nucleic acid testing in a tertiary care emergency department: evaluation and utility Open
Rapid sample-to-answer tests for detection of SARS-CoV-2 are emerging and data on their relative performance is urgently needed. We evaluated the analytical performance of two rapid nucleic acid tests, Cepheid Xpert ® Xpress SARS-CoV-2 and…
View article: Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation
Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation Open
View article: Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation
Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation Open
There is an urgent need for reliable high-throughput serological assays for the management of the ongoing COVID-19 pandemic. Preferably, the performance of serological tests for a novel virus should be determined with clinical specimens ag…
View article: Identification of novel antigen candidates for a tuberculosis vaccine in the adult zebrafish (Danio rerio)
Identification of novel antigen candidates for a tuberculosis vaccine in the adult zebrafish (Danio rerio) Open
Tuberculosis (TB) remains a major global health challenge and the development of a better vaccine takes center stage in fighting the disease. For this purpose, animal models that are capable of replicating the course of the disease and are…
View article: DNA-rokotus tehostaa Bacillus Calmette-Guerin -rokotteen mykobakteeri-infektiota vastaan antamaa suojaa seeprakalassa
DNA-rokotus tehostaa Bacillus Calmette-Guerin -rokotteen mykobakteeri-infektiota vastaan antamaa suojaa seeprakalassa Open