Maarit Oikarinen
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View article: Detection of enterovirus RNA in pancreas and lymphoid tissues of organ donors with type 1 diabetes
Detection of enterovirus RNA in pancreas and lymphoid tissues of organ donors with type 1 diabetes Open
View article: Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes
Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes Open
View article: Detection of enterovirus RNA in pancreas and lymphoid tissues of organ donors with type 1 diabetes
Detection of enterovirus RNA in pancreas and lymphoid tissues of organ donors with type 1 diabetes Open
Aims/hypothesis The nPOD-Virus group collaboratively applied innovative technologies to detect and sequence viral RNA in pancreas and other tissues from organ donors with type 1 diabetes. These analyses involved the largest number of pancr…
View article: Serum 25-hydroxyvitamin D and fatty acids in relation to the risk of microbial infections in children: The TRIGR Divia study
Serum 25-hydroxyvitamin D and fatty acids in relation to the risk of microbial infections in children: The TRIGR Divia study Open
In young children with increased susceptibility to type 1 diabetes, long-chain n-3 PUFAs may influence the risk of viral infections and immune response against the infections. However, this association may depend on the type of virus sugge…
View article: Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study Open
View article: Enterovirus Infections Are Associated With the Development of Celiac Disease in a Birth Cohort Study
Enterovirus Infections Are Associated With the Development of Celiac Disease in a Birth Cohort Study Open
Enterovirus and adenovirus infections have been linked to the development of celiac disease. We evaluated this association in children who developed biopsy-proven celiac disease (N = 41) during prospective observation starting from birth, …
View article: Differential Detection of Encapsidated versus Unencapsidated Enterovirus RNA in Samples Containing Pancreatic Enzymes—Relevance for Diabetes Studies
Differential Detection of Encapsidated versus Unencapsidated Enterovirus RNA in Samples Containing Pancreatic Enzymes—Relevance for Diabetes Studies Open
Using immunohistochemistry, enterovirus capsid proteins were demonstrated in pancreatic islets of patients with type 1 diabetes. Virus proteins are mainly located in beta cells, supporting the hypothesis that enterovirus infections may con…
View article: Detection of enterovirus protein and RNA in multiple tissues from nPOD organ donors with type 1 diabetes
Detection of enterovirus protein and RNA in multiple tissues from nPOD organ donors with type 1 diabetes Open
Epidemiological studies have shown an association between enterovirus (EV) infections and type 1 diabetes (T1D), and EV protein has been detected in the pancreatic islets of T1D patients. Here we correlated the detection of EVs in lymphoid…
View article: Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes
Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes Open
Enteroviruses, specifically of the Coxsackie B virus family, have been implicated in triggering islet autoimmunity and type 1 diabetes, but their presence in pancreata of patients with diabetes has not been fully confirmed.To detect the pr…
View article: Relative sensitivity of immunohistochemistry, multiple reaction monitoring mass spectrometry, in situ hybridization and PCR to detect Coxsackievirus B1 in A549 cells
Relative sensitivity of immunohistochemistry, multiple reaction monitoring mass spectrometry, in situ hybridization and PCR to detect Coxsackievirus B1 in A549 cells Open
View article: Detection of Enteroviruses in Tissue Samples - Methods and applications in type 1 diabetes
Detection of Enteroviruses in Tissue Samples - Methods and applications in type 1 diabetes Open
Tyypin 1 diabetes (T1D) johtuu haiman insuliinia tuottavien beetasolujen tuhoutumisesta immunologisten mekanismien kautta. Tapahtumaketju, joka johtaa sairastumiseen, on monimutkainen ja vielä osittain epäselvä. Taudin puhkeamista edeltää …