Explanipedia

O-228 T’easy: redefining sperm detection after testicular sperm extraction (TESE) – A faster, smarter and more efficient approach to sperm retrieval in IVF Labs Open

K Wouters, Martine De Meyer, Maarten Larmuseau, N. Franceus, M. D. Krunić , et al. · 2025

Study question Can we develop an automated tool for fast, accurate, and efficient sperm detection in TESE samples, optimizing retrieval and enhancing efficiency in the IVF workflow? Summary answer T’easy shows high recall and precision wit…

Urbanization and genetic homogenization in the medieval Low Countries revealed through a ten-century paleogenomic study of the city of Sint-Truiden Open

Owyn Beneker, Ludovica Molinaro, Meriam Guellil, Stefania Sasso, Helja Kabral , et al. · 2025

UYSD: a novel data repository accessible via public website for worldwide population frequencies of Y-SNP haplogroups Open

Arwin Ralf, Dion Zandstra, Bram van Wersch, Zehra Köksal, Maarten Larmuseau , et al. · 2025

For decades, there has been scientific interest in the variation and geographic distribution of paternal lineages associated with the human Y chromosome. However, the relevant data have been dispersed across numerous publications, making i…

“I’m trying to figure out who the hell I am”: Examining the psychosocial and mental health experience of individuals learning “Not Parent Expected” news from a direct-to-consumer DNA ancestry test Open

Juliette Careau, Maarten Larmuseau, Rebekah Drumsta, Rob Whitley · 2025

This study reveals an expanding, vulnerable, and under-researched population facing unique stressors, that may be at high risk of developing a psychiatric disorder. There is a need for new services and supports for this population includin…

Toward 3D facial analysis for recognizing Mendelian causes of autism spectrum disorder Open

Yoeri Sleyp, Harold Matthews, Michiel Vanneste, Laura Vandenhove, Valentine Delanote , et al. · 2024

Recognizing Mendelian causes is crucial in molecular diagnostics and counseling for patients with autism spectrum disorder (ASD). We explored facial dysmorphism and facial asymmetry in relation to genetic causes in ASD patients and studied…

Capturing the fusion of two ancestries and kinship structures in Merovingian Flanders Open

Stefania Sasso, Lehti Saag, Rachèl Spros, Owyn Beneker, Ludovica Molinaro , et al. · 2024

The Merovingian period (5th to 8th cc AD) was a time of demographic, socioeconomic, cultural, and political realignment in Western Europe. Here, we report the whole-genome shotgun sequence data of 30 human skeletal remains from a coastal L…

Ethisch verantwoord omgaan bij onderzoek van menselijk botmateriaal in Vlaanderen Open

Lien Van der Dooren, Jeroen Vanden Borre, Liesbeth Massagé, Katrien Van de Vijver, Maarten Larmuseau , et al. · 2024

Het project MEMOR kent vele moeders en vaders, en even\nveelzijdig als de betrokken wetenschappers zijn ook de oorzaken en redenen van het onderzoek.\nNaast het feit dat archeologen, opdrachtgevers, depotverantwoordelijken steeds vaker wor…

"Memor" : créer un inventaire des restes humaines archéologiques en Flandres, Belgique Open

Katrien Van de Vijver, Isabelle De Groote, Liesbeth Massagé, Jonas Danckers, Maarten Larmuseau , et al. · 2024

MEMOR: A database of archeological human remains collections from Flanders, Belgium Open

Isabelle De Groote, Katrien Van de Vijver, Barbara Veselka, Pieterjan De Potter, Liesbeth Massagé , et al. · 2023

The aim of this article is to describe a newly created open access database of archeological human remains collections from Flanders, Belgium. The MEMOR database ( www.memor.be ) was created to provide an overview of the current practices …

Genomic analyses of hair from Ludwig van Beethoven Open

Tristan James Alexander Begg, Axel Schmidt, Arthur Kocher, Maarten Larmuseau, Göran Runfeldt , et al. · 2023

Merovinger DNA. De genetische en archeologische synthese van een Merovingisch grafveld aan de Vlaamse kust Open

Maarten Larmuseau, Stefania Sasso, Alexander Lehouck, Jan Geypen, Rachèl Spros , et al. · 2023

Na de melding van een toevalsvondst in Koksijde (Ter Duinenlaan) werd begin 2017 een Laat-Merovingische bewoning en grafveld opgegraven door het agentschap Onroerend Erfgoed. Deze Koksijdse site bleek bijzonder waardevol te zijn door de aa…

Y-chromosome target enrichment reveals rapid expansion of haplogroup R1b-DF27 in Iberia during the Bronze Age transition Open

Carla García-Fernández, Esther Lizano, Marco Telford, Íñigo Olalde, Rafael de Cid , et al. · 2022

The Y chromosome can yield a unique perspective into the study of human demographic history. However, due to the repetitive nature of part of its sequence, only a small set of regions are suitable for variant calling and discovery from sho…

Large-scale pedigree analysis highlights rapidly mutating Y-chromosomal short tandem repeats for differentiating patrilineal relatives and predicting their degrees of consanguinity Open

Arwin Ralf, Diego Montiel González, Dion Zandstra, Bram van Wersch, Nefeli Kousouri , et al. · 2022

Rapidly mutating Y-chromosomal short tandem repeats (RM Y-STRs) were suggested for differentiating patrilineally related men as relevant in forensic genetics, anthropological genetics, and genetic genealogy. Empirical data are available fo…

Mommy's baby, daddy's maybe: Misattributed paternity in a nationwide blood group database Open

Maarten Larmuseau · 2021

With 'Mater certa, pater semper incertus', the Romans already had their own version of the more contemporary 'Mommy's baby, daddy's maybe'. These expressions refer to the ever-present uncertainty surrounding the biological bond between fat…

CSYseq: The first Y-chromosome sequencing tool typing a large number of Y-SNPs and Y-STRs to unravel worldwide human population genetics Open

Sofie Claerhout, Paulien Verstraete, Liesbeth Warnez, Simon Vanpaemel, Maarten Larmuseau , et al. · 2021

Male-specific Y-chromosome (chrY) polymorphisms are interesting components of the DNA for population genetics. While single nucleotide polymorphisms (Y-SNPs) indicate distant evolutionary ancestry, short tandem repeats (Y-STRs) are able to…

3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies Open

Hanne Hoskens, Dongjing Liu, Sahin Naqvi, Myoung Keun Lee, Ryan J. Eller , et al. · 2021

The analysis of contemporary genomic data typically operates on one-dimensional phenotypic measurements (e.g. standing height). Here we report on a data-driven, family-informed strategy to facial phenotyping that searches for biologically …

MerovingerDNA: de genetische synthese van een laat-Merovingisch grafveld aan de Vlaamse kust Open

Maarten Larmuseau, Alexander Lehouck, Stefania Sasso, Katrien Van de Vijver, Rachèl Spros , et al. · 2021

Subdividing Y-chromosome haplogroup R1a1 reveals Norse Viking dispersal lineages in Britain Open

Gurdeep Matharu Lall, Maarten Larmuseau, Jon H. Wetton, Chiara Batini, Pille Hallast , et al. · 2020

Identification and characterization of novel rapidly mutating Y‐chromosomal short tandem repeat markers Open

Arwin Ralf, Delano Lubach, Nefeli Kousouri, Christian Winkler, Iris Schulz , et al. · 2020

Short tandem repeat polymorphisms on the male‐specific part of the human Y‐chromosome (Y‐STRs) are valuable tools in many areas of human genetics. Although their paternal inheritance and moderate mutation rate (~10 −3 mutations per marker …

Unravelling the evolution of Africa’s drainage basins through a widespread freshwater fish, the African sharptooth catfish Clarias gariepinus Open

Maarten Van Steenberge, Maarten P. M. Vanhove, Auguste Chocha Manda, Maarten Larmuseau, Belinda L. Swart , et al. · 2020

Aim The formation history of Africa's current river basins remains largely unknown. In order to date changes in landscape and climate, we studied the biogeography of the African freshwater fish with the largest natural distribution. We als…

A Historical-Genetic Reconstruction of Human Extra-Pair Paternity Open

Maarten Larmuseau, Pieter van den Berg, Sofie Claerhout, Francesc Calafell, Alessio Boattini , et al. · 2019

Ysurnames? The patrilineal Y-chromosome and surname correlation for DNA kinship research Open

Sofie Claerhout, Jennifer Roelens, Michiel Van der Haegen, Paulien Verstraete, Maarten Larmuseau , et al. · 2019

Correction to: The Dutch Y-chromosomal landscape Open

Eveline Altena, Risha Smeding, Kristiaan J. van der Gaag, Maarten Larmuseau, Ronny Decorte , et al. · 2019

The Dutch Y-chromosomal landscape Open

Eveline Altena, Risha Smeding, Kristiaan J. van der Gaag, Maarten Larmuseau, Ronny Decorte , et al. · 2019

Estimating Y-Str Mutation Rates and Tmrca Through Deep-Rooting Italian Pedigrees Open

Alessio Boattini, Stefania Sarno, Alessandra M. Mazzarisi, Cinzia Viroli, Sara De Fanti , et al. · 2019

A game of hide and seq: Identification of parallel Y-STR evolution in deep-rooting pedigrees Open

Sofie Claerhout, Michiel Van der Haegen, Lisa Vangeel, Maarten Larmuseau, Ronny Decorte · 2018

Growth of ancestry DNA testing risks huge increase in paternity issues Open

Maarten Larmuseau · 2018

Spatially Dense 3D Facial Heritability and Modules of Co-heritability in a Father-Offspring Design Open

Hanne Hoskens, Jiarui Li, Karlijne Indencleef, Dorothy Gors, Maarten Larmuseau , et al. · 2018

Introduction: The human face is a complex trait displaying a strong genetic component as illustrated by various studies on facial heritability. Most of these start from sparse descriptions of facial shape using a limited set of land…

Recombination hotspots in an extended human pseudoautosomal domain predicted from double-strand break maps and characterized by sperm-based crossover analysis Open

Nitikorn Poriswanish, Rita Neumann, Jon H. Wetton, J. Wagstaff, Maarten Larmuseau , et al. · 2018

The human X and Y chromosomes are heteromorphic but share a region of homology at the tips of their short arms, pseudoautosomal region 1 (PAR1), that supports obligate crossover in male meiosis. Although the boundary between pseudoautosoma…

The black legend on the Spanish presence in the low countries: Verifying shared beliefs on genetic ancestry Open

Maarten Larmuseau, Francesc Calafell, Sarah A. Princen, Ronny Decorte, Violet Soen · 2018

Objectives War atrocities committed by the Spanish army in the Low Countries during the 16th century are so ingrained in the collective memory of Belgian and Dutch societies that they generally assume a signature of this history to be pres…

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