Mac Dionys Rodrigues da Costa
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View article: Care Bundle: Strategies for Managing Antimicrobials in a Reference Transplant Hospital in Northeastern Brazil
Care Bundle: Strategies for Managing Antimicrobials in a Reference Transplant Hospital in Northeastern Brazil Open
Introduction: Infections by multidrug-resistant bacteria represent a serious public health problem, especially among transplant patients who, due to immunosuppression, become more susceptible to opportunistic infections and resistant patho…
View article: Cymbopogon citratus Essential Oil Protects Tubular Renal Cells against Ischemia/Reoxygenation Injury - Involvement Nrf2/Keap1 Pathway
Cymbopogon citratus Essential Oil Protects Tubular Renal Cells against Ischemia/Reoxygenation Injury - Involvement Nrf2/Keap1 Pathway Open
Ischemia and reoxygenation (I/R) cause acute kidney injury with progression related to oxidative damage, mitochondrial dysfunction and cell death. Nrf2-Keap1 pathway is involved in this process. Cymbopogon citratus, used in popular medicin…
View article: Single-nucleotide polymorphism rs670 in the promoter region of the apolipoprotein A-I gene
Single-nucleotide polymorphism rs670 in the promoter region of the apolipoprotein A-I gene Open
Apolipoprotein A-I (Apo A-I) plays a central role in the function of high-density lipoprotein (HDL). The rs670 single-nucleotide polymorphism (SNP) was identified as a cytosine-to-thymine (C>T) transition in a cytosine–phosphate&ndas…
View article: Urinary cystatin-C and urinary NGAL associated with sepsis predicts longer hospital stay in premature newborns
Urinary cystatin-C and urinary NGAL associated with sepsis predicts longer hospital stay in premature newborns Open
Aim: To evaluate the urinary biomarkers related to sepsis in preterm newborns (NBs) and to investigate the predictive capacity of these biomarkers for a longer hospital stay.Methods: Serum and urine were collected from 27 healthy NBs, 24 N…
View article: Evidence of obesity-induced inflammatory changes in client-owned cats
Evidence of obesity-induced inflammatory changes in client-owned cats Open
Background and Aim: Insulin resistance and type 2 diabetes mellitus are common health issues in obese (OB) cats. In humans, obesity leads to alterations in adipokine and proinflammatory cytokine secretion, causing persistent inflammation. …
View article: Correlation of Apolipoprotein a-i with Renal Function in Diabetic Patients
Correlation of Apolipoprotein a-i with Renal Function in Diabetic Patients Open
Diabetes mellitus (DM) is a major cause of chronic kidney disease (CKD) and changes in lipoprotein. Literature data suggest that cholesterol associated with high-density lipoprotein (HDLc) plays a protective role against albuminuria and di…
View article: Association of serum lipoproteins and inflammatory parameters derived from the blood test with renal function in COVID-19 outpatients
Association of serum lipoproteins and inflammatory parameters derived from the blood test with renal function in COVID-19 outpatients Open
Changes in lipoprotein metabolism are among the main causes of hemodynamic impairment in renal function. COVID-19 is an multisystemic inflammatory disease, aggravating this situation. This cross-sectional study investigated the relationshi…
View article: Protective Effect of Quercetin on Renal Tubular Cells and the Involvement with the Renin-Angiotensin-Aldosterone Axis
Protective Effect of Quercetin on Renal Tubular Cells and the Involvement with the Renin-Angiotensin-Aldosterone Axis Open
Ischemia-reperfusion (I/R) plays an important role in the process of acute kidney injury (AKI) due to the generation of reactive oxygen species (ROS). Substances of natural origin have been studied in the prevention of oxidative damage rel…