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Prophylactic treatment with amnion progenitor cell secretome mitigates traumatic optic neuropathy Open
Traumatic optic neuropathy (TON), often resulting from repetitive mild traumatic brain injury (r-mTBI), is a major contributor to irreversible visual impairment, with few preventive therapeutic options available. This study evaluates the p…
PPARγ activation ameliorates cognitive impairment and chronic microglial activation in the aftermath of r-mTBI Open
Chronic neuroinflammation and microglial activation are key mediators of the secondary injury cascades and cognitive impairment that follow exposure to repetitive mild traumatic brain injury (r-mTBI). Peroxisome proliferator-activated rece…
Human amnionic progenitor cell secretome mitigates the consequence of traumatic optic neuropathy in a mouse model Open
Traumatic optic neuropathy (TON) is a condition in which acute injury to the optic nerve from direct or indirect trauma results in vision loss. The most common cause of TON is indirect injury to the optic nerve caused by concussive forces …