Explanipedia

Profile Of Antihypertensive Drug Use In Patients With Coronary Artery Disease At Prof. Dr. I.G.N.G. Ngoerah General Hospital (RSUP) In 2023 Open

Jainal Arifin, Ida Ayu Alit Widhiartini, I Made Jawi · 2025

Background: Coronary heart disease (CHD) is often triggered by atherosclerosis, with hypertension as a major risk factor. Managing hypertension through lifestyle modification and pharmacological therapy, such as ACE inhibitors, ARBs, beta-…

Association between phase angle and ECW/TBW ratio with body composition in individuals with central obesity: a cross-sectional study Open

Agustinus I Wayan Harimawan, Anak Agung Sagung Mirah Prabandari, Desak Made Wihandani, I Made Jawi, I Wayan Weta , et al. · 2025

Background Central obesity is closely linked with increased metabolic risk, systemic inflammation, and adverse outcomes. Bioelectrical impedance analysis (BIA) provides phase angle (PhA) and extracellular water to total body water (ECW/TBW…

Non-Invasive Prenatal Testing with Next Generation Sequencing Methods in Birth Defect Pregnancy: A Pilot Study Open

Anom Suardika, Anak Agung Ngurah Jaya Kusuma, Ni Gusti Ayu Manik Ermayanti, Endang Sri Widiyanti, I Gusti Ngurah Agung Satria Wibawa , et al. · 2025

BACKGROUND: Identification of cell-free foetal DNA (cffDNA) in maternal blood, combined with next-generation sequencing (NGS) advancement, has paved the way for non-invasive prenatal screening to detect foetal aneuploidies. However, there …

Karakteristik penderita karsinoma laring di Poliklinik THT-KL RSUP Prof. I. G. N. G. Ngoerah Denpasar periode tahun 2019 – 2023 Open

I Ketut Suanda, I Made Jawi, I Gde Ardika Nuaba, Indra Lesmana, Ni Komang Tri Utami Handayani Sutarta · 2025

Background: Laryngeal carcinoma is an increasingly prevalent head and neck malignancy in Indonesia, particularly among elderly males. Knowledge of patient characteristics is essential for guiding management strategies and prevention. There…

Slow 0.9% NaCl Bolus Administration Reduces ANP, MMP-2, and Syndecan-1 Shedding in Septic Shock Rabbit Models Open

I Nyoman Budi Hartawan, Made Wiryana, I Made Jawi, I Nyoman Mantik Astawa, I Made Bakta , et al. · 2025

Background: The optimal rate for fluid bolus administration in septic shock remains a critical and unresolved question. Rapid bolus administration is commonly practiced but has been linked to elevated levels of atrial natriuretic peptide (…

Expression of CD8+ and Foxp3+ T Lymphocyte as Predictor for Response to Neoadjuvant Chemotherapy in Stage III Breast Cancer Open

I Nyoman Wawan Tirtha Yasa, I Wayan Sudarsa, I Wayan Niryana, Ni Putu Sriwidyani, I Made Jawi , et al. · 2025

BACKGROUND: Neoadjuvant chemotherapy (NAC) in breast cancer is usually utilized to eradicate micro-metastasis, induce apoptosis in tumor cells, and reduce the primary tumor size, enabling surgical intervention. Recent studies have shown th…

Light physical activity and vitamin D improve sperm quality of male Rattus norvegicus exposed to cigarette smoke Open

Mauricio Amaral, Bagus Komang Satriyasa, I Wayan Putu Sutirta Yasa, I Made Sudarmaja, I Made Jawi , et al. · 2025

Background: Male infertility is a significant global health issue, with rising prevalence linked to environmental factors such as secondhand smoke, which impairs sperm quality. This study aimed to examine how light physical activity and vi…

Analysis of Q-Angle as a Risk Factor for Patellofemoral Pain Syndrome in Volleyball Athletes: A Cross-Sectional Study Open

Ni Ketut Evitri Widhiantari, M. Widnyana, I Made Jawi, Agung Wiwiek Indrayani · 2025

Introduction: Patellofemoral Pain Syndrome (PFPS) is a common knee injury caused by excessive loading during knee flexion, such as running or jumping, frequently experienced by volleyball athletes. One of the primary risk factors is an inc…

Pilot study on the effectiveness of Sidhakarya meditation in reducing malondialdehyde levels: an experimental approach Open

Santosa Imam, I Made Jawi, Cokorda Bagus Jaya Lesmana, Yenni Kandarini, Ida Bagus Yorky Brahmantya , et al. · 2025

Introduction: Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidants, contributes to chronic diseases. Malondialdehyde (MDA), a marker of oxidative damage, is commonly used to assess this stress. Me…

Oral administration Of Gedi Leaves Extract (Abelmoschus Manihot) Increased Glp-1 Serum and Decreased Fasting Glucose Level on Hyperglycaemia Male White Rat (Rattus Novergicus) Open

Erynne Gracia Monica Sheriman, I Made Jawi, I Made Winarsa Ruma · 2025

Synergistic Antifungal Effects of Gardenia augusta and Averrhoa bilimbi Leaf Extracts Against Candida albicans: Implications for the Treatment of Oral Candidiasis In Vitro Study Open

Pande Putu Karina Candra, I Made Jawi, I Gusti Ayu Artini, I Gusti Made Gde Surya Chandra Trapika · 2025

Oral candidiasis, commonly known as thrush, is a frequent fungal infection caused by Candida albicans that can lead to painful canker sores and more severe complications. Conventional treatments may have side effects, necessitating the exp…

Phytochemicals of Beluntas (Pluchea indica(L) Less.) and their health benefits Open

Putu Wira Kusuma Putra, I Made Jawi, Anak Agung Ngurah Subawa, Nyoman Mantik Astawa, Agung Wiwiek Indrayani , et al. · 2025

Bioactive compounds derived from plants are acquiring global popularity due to their safety and diverse applications as medicinal agents. Beluntas, also known as Pluchea indica, is a shrub abundantly found in coastal regions and is rich in…

Penggunaan Obat Antivirus Bagi Penderita COVID – 19 di RS Universitas Udayana Tahun 2022 – 2023 Open

Kadek Agastya Widya Sedana Grudug, I Made Jawi, I Gusti Ayu Artini · 2024

COVID-19, yang disebabkan oleh virus SARS-CoV-2, pertama kali ditemukan di Wuhan, Cina, dan menjadi ancaman kesehatan global sejak awal 2020. Penelitian mengenai penggunaan obat antivirus di RS Universitas Udayana pada 2022-2023 penting un…

The Role of Mesenchymal Stem Cells for Corneal Endothelial Regeneration: A Systematic Review Open

Siska Siska, I Gede Eka Wiratnaya, I Made Bakta, I Made Jawi, I Gde Raka Widiana , et al. · 2024

Objective: A single layer of tightly spaced cells, known as the endothelium, rests on the posterior side of the cornea. This endothelium regulates the stroma’s relative dehydration, which is essential for corneal clarity. Cell therapy is a…

Phytoconstituent and In silico Screening of Active Compounds from Red Ginger (Zingiber officinale var. rubrum Theilade) Rhizome and Avocado (Persea americana Mill.) Leaves Extracts as Novel Inhibitors of MRSA Open

Ni Kadek Yunita Sari, Putu Angga Wiradana, Anak Agung Ayu Putri Permatasari, I Gede Widhiantara, Novaria Sari Dewi Panjaitan , et al. · 2024

Red ginger rhizome (Zingiber officinale var. Rubrum) and avocado leaves (Persea americana Mill.) are empirically known as one of the medicinal plants used in Taro Village, Gianyar Regency, Bali which have great potential in treating infect…

The effect of meditation on telomerase and stem cell Open

I. Gusti Ngurah Putra Eka Santosa, I Made Jawi, I Made Bakta, I Wayan Putu Sutirta Yasa, I Made Ady Wirawan , et al. · 2024

Meditation has garnered increasing interest due to its potential effects on cellular aging processes, particularly telomere and stem cells. This narrative review aims to synthesize existing research on how meditation affects telomeres and …

Effects of Moleac 901 after severe spinal cord injury on chronic phase in Wistar rats Open

Dewa Putu Wisnu Wardhana, Sri Maliawan, Tjokorda Gde Bagus Mahadewa, Andi Asadul Islam, I Made Jawi , et al. · 2024

MLC901 positively affects motor and histopathological outcomes in the chronic phase of severe SCI in the Wistar rat model. These benefits are believed to be achieved by suppressing gliosis, neuroapoptosis, and neuroinflammation processes.

SCREENING OF ALPHA-GLUCOSIDASE INHIBITORY ACTIVITY FROM TWO PRODUCTS OF THE CAPSULIZED JAMU CINNAMON EXTRACT (CINNMOMUM BURMANNII) Open

Larasati Hanifa Febrianda, I Made Jawi, Ida Ayu Alit Widiarthini, I Gusti Made Aman · 2024

Cinnamon (Cinnamomim burmannii) found in the markets, comes in many forms with one of them being a type of jamu which the cinnamon dust is capsulized. The capsulized jamu is claimed to be beneficial on treating diabetes melitus. The effe…

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BUAH JUWET (Syzygium Cumini) TERHADAP PERTUMBUHAN Staphylococcus EpidermidisPENYEBAB ACNE VULGARIS Open

Kadek Wina Santhya Putri, I Made Jawi, Agung Wiwiek Indrayani, Agung Nova Mahendra · 2024

Acne vulgaris merupakan permasalahan yang banyak dialami oleh masyarakat baik pria dan wanita. Salah satu penyebab terjadinya acne vulgaris adalah Staphylococcus epidermidis yaitu bakteri gram positif yang normal berada di kulit, namun dal…

Evaluation of the antiatherogenic potential of purple sweet potato (Ipomoea batatas L.) extracts in Wistar rats exposed to a high-cholesterol diet Open

I Made Jawi, I Wayan Putu Sutirta Yasa, I Gede Widhiantara · 2024

by various causes, one of which is dyslipidemia.Dyslipidemia, caused mainly by an increase in low-density lipoprotein (LDL) cholesterol, may lead to endothelial dysfunction [2] and is susceptible to oxidative stress and the formation of ox…

Safe and effective dosage combination of purple sweet potato extract and red fruit oil extract as antioxidant and hypolipidemic in rats given high cholesterol feed Open

I Made Jawi, Anak Agung Ngurah Subawa, I Wayan Putu Sutirta Yasa, I Putu Eka Widyadharma · 2023

Safe and effective dosage combination of purple sweet potato extract and red fruit oil extract as antioxidant and hypolipidemic in rats given high cholesterol feed

Risk factors of the patellofemoral pain syndrome Open

Ni Ketut Evitri Widhiantari, M. Widnyana, I Made Jawi · 2023

Background: Patellofemoral pain syndrome (PFPS) is one of the common injuries to the knee that often occur, causing pain when doing physical activities such as squatting, running or going up and down stairs when the knee is bent. As the jo…

Vitamin D Status of the Adult Population in Bali and Its Relationship to Anthropometry and Body Fat: A Cross-Sectional Study Open

Putu Adi Suputra, I Made Jawi, Susy Purnawati, I Made Muliarta · 2023

Introduction: In both children and adults, obesity is frequently correlated with low levels of vitamin D. The metabolic syndrome and insulin resistance have both been linked to people with low vitamin D levels.Low vitamin D levels and a hi…

A Review on Individual Based Nutrition and Role of Genetic Open

Ni Putu Yenny Kendarini, Prayuda Prayuda, I Made Jawi · 2023

Health is a result of interactions between genes and environmental factors. The environmental factors that most significantly influence human health are nutrition, diet and daily lifestyle. Individual-based nutrition is an approach that re…

Inhibition Test of Sambiloto (Andrographis paniculata Nees) and Moringa (Moringa oleifera L.) Leaves Ethanol Extract Against Streptococcus pyogenes Bacteria Open

Kadek Prastiti Surya Pratiwi, I Made Jawi, Agung Wiwiek Indrayani, Agung Nova Mahendra · 2023

Cases of infection and antibiotic resistance by Streptococcus pyogenes are increasing. Sambiloto leaf has unique phytochemical, namely andrographolide as antibacterial and other phytochemicals such as alkaloids, flavonoids, phenols, saponi…

PERBANDINGAN PENGARUH PEMBERIAN JUS BUAH NAGA MERAH(HYLOCEREUS POLYRHIZUS) DENGAN OBAT SIMVASTATIN TERHADAP PENURUNAN KADAR KOLESTEROL DARAH MENCIT (MUS MUSCULUS) DENGAN KONDISI HIPERKOLESTEROLEMIA Open

Gayus Erino Nabasa, I Made Jawi, Bagus Komang Satriyasa · 2023

This study aims to determine the effect of giving red dragon fruit juice with graded doses on reducing total cholesterol levels of mice with hypercholesterolemic conditions. This research was conducted to prove the anti-cholesterol effec…

EKSTRAK ETANOL UMBI UBI JALAR UNGU (Ipomoea batatas L) MENINGKATKAN KETEBALAN ENDOMETRIUM Open

Desak Putu Citra Udiyani, I Made Jawi, Wayan Sugiritama, I Gusti Kamasan Nyoman Arijana, Komang Trisna Sumadewi · 2023

Menopause merupakan salah satu proses yang alami untuk Wanita, dengan terapi Hormone Replacement Therapy (HRT) menimbulkan efek endometriosis dan tromboemboli vena. Umbi ubi jalar ungu (Ipomoea batatas L) merupakan tumbuhan dengan antosian…

The potential of MLC901 as adjuvant therapy for traumatic spinal cord injury by multi-pathway biomechanism: a systematic review Open

Dewa Putu Wisnu Wardhana, Agung Bagus Sista Satyarsa, Rohadi Muhammad Rosyid, Husni Harmansyah, Tjokorda Gde Bagus Mahadewa , et al. · 2023

Background: Traumatic spinal cord injury (tSCI) is a severe neurological condition that causes long-term nerve function impairment and can even cause death. Further efforts are needed to find better therapy for this condition to improve pa…

KESESUAIAN PERESEPAN ANTIBIOTIKA PADA BERBAGAI TINGKAT KEPARAHAN COVID-19 DI PELAYANAN KESEHATAN RUJUKAN Open

Leonardo Alpha Diaz, I Made Jawi, Ida Ayu Alit Widhiartini, I Gusti Made Aman · 2023

COVID-19 telah menghadapkan klinisi dengan sebuah tantangan baru dimana belum ditemukannya terapi definitif dalam penanganan penyakit tersebut hingga tahun 2021. COVID-19 dapat menyebabkan disregulasi daya tahan tubuh pada sebagian pasien,…

Oral Administration of Ethanol Extract of Moringa Leaves (Moringa oleifera) Reduces F2-Isoprostane and Monocyte Chemoattractant Protein (MCP-1) Levels in Wistar Rats (Rattus norvegicus) as an Obesity Model Open

Stefani Krisanti, Agus Eka Darwinata, I Made Jawi · 2023

Background: Obesity is a chronic condition causes oxidative stress and low-grade chronic inflammation characterized by increased oxidative stress biomarkers F2-Isoprostane and proinflammatory biomarkers Monocyte Chemoattractant Protein (MC…

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