Explanipedia

In-hospital exercise interventions improve inpatients’ frailty and demonstrate promising implementation outcomes: A systematic review and meta-analysis Open

Madeline E. Shivgulam, Haoxuan Liu, Zuha Zafar, Muhammad Arshad Cheema, Shirko Ahmadi , et al. · 2025

Despite limited available evidence, results indicate exercise training interventions may be effective in improving frailty. This supports the inclusion of exercise interventions beyond usual hospital care to improve frailty.

Exercise Interventions Improve Frailty in Patients Living in Long-Term Care: A Systematic Review and Meta-Analysis Open

Madeline E. Shivgulam, Haoxuan Liu, Zuha Zafar, Muhammad Arshad Cheema, Shirko Ahmadi , et al. · 2025

This review and meta-analysis support that exercise training is an effective model of improving frailty levels among older adults in long-term care. Strategies to address the practical aspects of these programs are needed, but this study e…

Becoming mindful of mindfulness: a promising approach to reducing sympathetic nervous system overactivity in chronic kidney disease Open

Molly K. Courish, Carson Halliwell, Cory A. Munroe, Beverly D. Schwartz, Madeline E. Shivgulam , et al. · 2025

How are exercise professionals described within academic literature? A narrative review Open

Madeline E. Shivgulam, Abigail R. Tiemstra, Bob Hebert, Jonathon R. Fowles, Myles W. O’Brien , et al. · 2025

There is growing interest to include exercise into healthcare for the prevention, treatment, and management of chronic disease. However, what defines an “exercise professional” to fulfil these roles and responsibilities is not clear across…

Meeting international self-report muscle strengthening guidelines is associated with better cardiovagal baroreflex sensitivity in adults Open

Jocelyn Waghorn, Beverly D. Schwartz, Madeline E. Shivgulam, Yanlin Wu, Derek S. Kimmerly , et al. · 2024

Engaging in muscle strengthening activities (e.g., resistance training) at least twice/week is promoted by (Inter)national movement guidelines. Cardiovagal baroreflex sensitivity (cvBRS) reflects the ability to modulate R-R interval in res…

Moderate intensity intermittent lifestyle physical activity is associated with better executive function in older adults Open

Emily MacDonald, E Morrison, Madeline E. Shivgulam, Liam P. Pellerine, Derek S. Kimmerly , et al. · 2024

Executive functions are among the first cognitive abilities to decline with age and age-related executive function slowing predisposes older adults to cognitive disorders and disease. Intermittent Lifestyle Physical Activity (ILPA) reflect…

Effectiveness of <span>contrast‐enhanced</span> duplex ultrasound for detecting renal artery stenosis: A systematic review Open

Madeline E. Shivgulam, Haoxuan Liu, Matthew J. Kivell, Jessica MacLeod, Myles W. O’Brien · 2024

Purpose Contrast‐enhanced duplex ultrasound (CEUS) might be a useful tool to diagnosing renal artery stenosis (RAS). We amalgamated and reviewed the evidence assessing the diagnostic accuracy of CEUS on detecting RAS compared to angiograph…

Effectiveness of physical activity counselling and exercise prescription education among medical students: a systematic review Open

Madeline E. Shivgulam, Jennifer L. Petterson, Liam P. Pellerine, Matthew J. Kivell, Taylor M. Wilson , et al. · 2024

Background: Providing physical activity counselling and prescribing exercise increases patients’ activity and cardiorespiratory fitness, but healthcare providers experience challenges in promoting activity to patients. Implementing educati…

Sitting knee-flexion angle does not influence endothelial-dependent vasodilation in laboratory or free-living conditions Open

Madeline E. Shivgulam, Myles W. O’Brien, Yanlin Wu, Haoxuan Liu, Jennifer L. Petterson , et al. · 2024

Introduction: Single bouts of prolonged bent-legged sitting attenuate popliteal endothelial-dependent vasodilation (as assessed via flow-mediated dilation [FMD]), which is partially attributed to arterial ‘kinking’. However, the impact of …

Accuracy of Duplex Ultrasound for Detecting Renal Artery Stenosis: A Systematic Review Open

Jessica MacLeod, Matthew J. Kivell, Madeline E. Shivgulam, Haoxuan Liu, Myles W. O’Brien · 2024

Background: Duplex ultrasound (DUS) is a well-tolerated, noninvasive imaging technique. Renal artery stenosis (RAS)—a narrowing of the arteries that supply the kidney—is involved in the cause of renal failure, and its gold-standard method …

Exercise Training Recommendations for Adults With and Without Chronic Disease to Improve Endothelial Health Open

Madeline E. Shivgulam, Myles W. O’Brien · 2023

The endothelium is the innermost layer of the blood vessels and is responsible for the production of chemicals that are used to regulate arterial diameter in response to changes in blood flow. Dysfunction of the endothelium is a key precur…

Validity of ActivPAL CREA software detection of sitting and lying during free-living conditions Open

Madeline E. Shivgulam, Ryan J. Frayne, Beverly D. Schwartz, Yanlin Wu, W Seth Daley , et al. · 2023

Objective . Approaches to differentiate sitting and lying are available within the default activPAL software from a single thigh-worn monitor. Dual-monitor methods use multiple monitors positioned on the thigh and torso to characterize sit…

Disagreements in physical activity monitor validation study guidelines create challenges in conducting validity studies Open

Myles W. O’Brien, Liam P. Pellerine, Madeline E. Shivgulam, Derek S. Kimmerly · 2023

OPINION article Front. Digit. Health, 10 January 2023Sec. Human Factors and Digital Health Volume 4 - 2022 | https://doi.org/10.3389/fdgth.2022.1063324

Characterization of Detailed Sedentary Postures Using a Tri-Monitor ActivPAL Configuration in Free-Living Conditions Open

Myles W. O’Brien, W. Seth Daley, Beverly D. Schwartz, Madeline E. Shivgulam, Yanlin Wu , et al. · 2023

Objective monitors such as the activPAL characterize time when the thigh is horizontal as sedentary time. However, there are physiological differences between lying, bent-legged sitting, and straight-legged sitting. We introduce a three-mo…

Exercise training augments brain function and reduces pain perception in adults with chronic pain: A systematic review of intervention studies Open

Kierstyn L. Palmer, Madeline E. Shivgulam, Anne Sophie Champod, Brian C. Wilson, Myles W. O’Brien , et al. · 2023

Our review suggests that alterations in brain function, notably the cortico-limbic, default-mode and dorsolateral prefrontal cortex, may be responsible for the downstream improvements in the subjective experience of CP. Through appropriate…

30 Year Trends of Reduced Physical Fitness in Undergraduate Students Studying Human Movement Open

Myles W. O’Brien, Madeline E. Shivgulam, William Robert Wojcik, Brittany A. Barron, Roxanne E. Seaman , et al. · 2022

The physical fitness of Canadian adults has decreased over the past 30 years, while sedentary time has increased. However, it is unknown if university students studying human movement exhibit similar population declines. Physical fitness (…

Habitual sedentary time and stationary time are inversely related to aerobic fitness Open

Myles W. O’Brien, Madeline E. Shivgulam, Jennifer L. Petterson, Yanlin Wu, Ryan J. Frayne , et al. · 2022

The Impact of Exercise Training Interventions on Flow-Mediated Dilation: An Umbrella Review Protocol Open

Myles W. O’Brien, Haoxuan Liu, Madeline E. Shivgulam, Jodi Langley, Nick W. Bray , et al. · 2022

Introduction. (Cardio)vascular diseases are among the top causes of death in western societies. The impact of exercise training interventions to improve endothelial-dependent, flow-mediated dilation (FMD) responses has been reviewed extens…

Impact of habitual sedentary patterns on popliteal artery endothelial-dependent vasodilation in healthy adults Open

Madeline E. Shivgulam, Myles W. O’Brien, Jarrett A. Johns, Jennifer L. Petterson, Yanlin Wu , et al. · 2022

Introduction: Acute, laboratory-based bouts of prolonged sitting attenuate lower-limb arterial endothelial-dependent vasodilation. However, the impact of habitual sedentary patterns on popliteal artery endothelial health is unclear. We tes…

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