Madeline G. Rollins
YOU?
Author Swipe
View article: 6.6 – 00176 CAR/CCR9 T cell immunotherapy shows promise in localization of SIV-specific CAR T cells to the gastrointestinal tract of rhesus macaques
6.6 – 00176 CAR/CCR9 T cell immunotherapy shows promise in localization of SIV-specific CAR T cells to the gastrointestinal tract of rhesus macaques Open
View article: Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome
Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome Open
View article: Proteomic and mechanistic dissection of the poxvirus-customized ribosome
Proteomic and mechanistic dissection of the poxvirus-customized ribosome Open
Ribosomes are often viewed as protein synthesis machines that lack intrinsic regulatory capacity. However, studies have established that ribosomes can functionally diversify through changes in the composition of, or post-translational modi…
View article: RACK1 evolved species-specific multifunctionality in translational control through sequence plasticity in a loop domain
RACK1 evolved species-specific multifunctionality in translational control through sequence plasticity in a loop domain Open
Receptor of Activated C Kinase 1 (RACK1) is a highly conserved eukaryotic protein that regulates several aspects of mRNA translation, yet how it does so remains poorly understood. Here we show that although RACK1 consists largely of conser…
View article: A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies
A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies Open
Amyloid β oligomers (AβOs) accumulate early in Alzheimer's disease ( AD ) and experimentally cause memory dysfunction and the major pathologies associated with AD , for example, tau abnormalities, synapse loss, oxidative damage, and cognit…
View article: Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit
Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit Open
View article: ZNF598 Plays Distinct Roles in Interferon-Stimulated Gene Expression and Poxvirus Protein Synthesis
ZNF598 Plays Distinct Roles in Interferon-Stimulated Gene Expression and Poxvirus Protein Synthesis Open
Post-translational modification of ribosomal subunit proteins (RPs) is emerging as an important means of regulating gene expression. Recently, regulatory ubiquitination of small RPs RPS10 and RPS20 by the ubiquitin ligase ZNF598 was found …
View article: Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station.
Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station. Open
Toxic amyloid beta oligomers (AβOs) are known to accumulate in Alzheimer's disease (AD) and in animal models of AD. Their structure is heterogeneous, and they are found in both intracellular and extracellular milieu. When given to CNS cult…