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View article: Role of FlhF and its domains in the assembly of a polar flagellum in <i>P. aeruginosa</i>
Role of FlhF and its domains in the assembly of a polar flagellum in <i>P. aeruginosa</i> Open
FlhF, an SRP GTPase, regulates the polarity and flagellation patterns in various bacteria, including Pseudomonas aeruginosa . FlhF is a multidomain protein that comprises three domains: B, N, and G, or the GTPase domain. However, the roles…
View article: Emetine dihydrochloride inhibits Chikungunya virus nsP2 helicase and shows antiviral activity in the cell culture and mouse model of virus infection
Emetine dihydrochloride inhibits Chikungunya virus nsP2 helicase and shows antiviral activity in the cell culture and mouse model of virus infection Open
Chikungunya virus (CHIKV), a mosquito-borne alphavirus, causes frequent epidemics of chikungunya fever across the world and has become a significant medical challenge, warranting the development of novel antivirals. A cell imaging-based hi…
View article: Fabrication of novel red light emitting PVA/ZnO: Eu3+ electrospun composite nanofibers
Fabrication of novel red light emitting PVA/ZnO: Eu3+ electrospun composite nanofibers Open
Polyvinyl Alcohol (PVA)/ZnO: Eu3+ composite nanofibers (NFs) have been successfully prepared by Electrospinning technique. The crystal structure, surface morphology, distribution of elements and photoluminescence properties of composite NF…
View article: Viability of Automating Annotation through MediaPipe’s Effectiveness on Pose Points Model Accuracy
Viability of Automating Annotation through MediaPipe’s Effectiveness on Pose Points Model Accuracy Open
This research investigates the effectiveness of automated annotation using MediaPipe for human motion recognition tasks, comparing its performance against manually annotated data from the MP2 dataset. Through the evaluation of three machin…
View article: Universal Superconductivity in FeTe and All‐Iron‐Based Ferromagnetic Superconductor Heterostructures
Universal Superconductivity in FeTe and All‐Iron‐Based Ferromagnetic Superconductor Heterostructures Open
Ferromagnetism (FM) and superconductivity (SC) are two of the most famous macroscopic quantum phenomena. However, nature normally does not allow SC and FM to coexist without significant degradation. Here, the first fully iron‐based SC/FM h…
View article: Youth's Online Privacy Concerns: An Examination of Social Media Platforms' Data Protection Policies
Youth's Online Privacy Concerns: An Examination of Social Media Platforms' Data Protection Policies Open
Social media platforms have become a central part of youth culture in India, offering avenues for communication, social interaction, and self-expression. However, these platforms also pose significant risks related to data privacy and secu…
View article: Withaferin A inhibits Chikungunya virus nsP2 protease and shows antiviral activity in the cell culture and mouse model of virus infection
Withaferin A inhibits Chikungunya virus nsP2 protease and shows antiviral activity in the cell culture and mouse model of virus infection Open
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus causing fever, myalgia, and debilitating joint swelling and pain, which in many patients becomes chronic. The frequent epidemics of CHIKV across the world pose a significant pu…
View article: Role of Nocardia sp. bioactives in regulating the key molecular checkpoints in quorum-sensing pathways of P. aeruginosa: application towards improved fabrication of medical devices
Role of Nocardia sp. bioactives in regulating the key molecular checkpoints in quorum-sensing pathways of P. aeruginosa: application towards improved fabrication of medical devices Open
AIM: Understanding the inhibitory role of bioactives from a novel Nocardia sp. against P. aeruginosa's Quorum-Sensing (QS) regulatory pathways and fabrication of effective foley catheters. BACKGROUND: P. aeruginosa‘s antimicrobial resistan…
View article: Travel Heaven
Travel Heaven Open
The objective of this paper is to design and develop a comprehensive online accommodation platform aimed at simplifying the process of listing, searching, and booking accommodations for both travellers and property owners. The platform see…
View article: Mystery of superconductivity in FeTe films and the role of neighboring layers
Mystery of superconductivity in FeTe films and the role of neighboring layers Open
Since the discovery of superconductivity in the Fe(Te,Se) system, it has been a general consensus that the end member of FeTe is not superconducting. Nonetheless, in recent years, there have been reports of superconducting FeTe films, but …
View article: Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease
Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease Open
Co-inheritance of α-thalassemia has a significant protective effect on the severity of complications of sickle cell disease (SCD), including stroke. However, little information exists on the association and interactions for the common Afri…
View article: Efficacy of Nitrofurantoin and Fosfomycin against Extended Spectrum Beta Lactamase Producing Uropathogens in the Era of Antibiotic Resistance: A Cross-sectional Study
Efficacy of Nitrofurantoin and Fosfomycin against Extended Spectrum Beta Lactamase Producing Uropathogens in the Era of Antibiotic Resistance: A Cross-sectional Study Open
Background: Urinary Tract Infection (UTI) is one of the most common bacterial infections that require medical care. It accounts for 25% of all infections. Limited number of antibiotics are available for the treatment of UTI due to increase…
View article: Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants
Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants Open
Chronic obstructive pulmonary disease (COPD), diagnosed by reduced lung function, is a leading cause of morbidity and mortality. We performed whole genome sequence (WGS) analysis of lung function and COPD in a multi-ethnic sample of 11,497…
View article: Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program
Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program Open
Hemoglobin A1c (HbA1c) is widely used to diagnose diabetes and assess glycemic control in individuals with diabetes. However, nonglycemic determinants, including genetic variation, may influence how accurately HbA1c reflects underlying gly…
View article: Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program Open
The genetic determinants of fasting glucose (FG) and fasting insulin (FI) have been studied mostly through genome arrays, resulting in over 100 associated variants. We extended this work with high-coverage whole genome sequencing analyses …
View article: Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension
Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension Open
Background: The availability of whole-genome sequencing data in large studies has enabled the assessment of coding and noncoding variants across the allele frequency spectrum for their associations with blood pressure. Methods: We conducte…
View article: Investigation of elastic scattering cross-sections of electron with neon atoms
Investigation of elastic scattering cross-sections of electron with neon atoms Open
In the present study, Integral [QI(E)], Momentum transfer [QM(E)] and Total [QT(E)] cross-sections have been successfully determined for the elastic scattering of electrons with Neon (Ne) atoms in intermediate incident energy range (100 – …
View article: Electrodynamics of the quantum anomalous Hall state in a magnetically doped topological insulator
Electrodynamics of the quantum anomalous Hall state in a magnetically doped topological insulator Open
Magnetically doped topological insulators have been extensively studied over the past decade as a material platform to exhibit quantum anomalous Hall effect. Most material realizations are magnetically doped and despite material advances s…
View article: Transformer-based models for hate speech classification
Transformer-based models for hate speech classification Open
This research paper explores the application of text classification and natural language processing techniques for enhancing hate speech detection. The study employs machine learning (ML) and deep learning models, including transformer mod…
View article: Signatures of Majorana Bound States in the Diffraction Patterns of Extended Superconductor-Topological Insulator-Superconductor Josephson Junctions
Signatures of Majorana Bound States in the Diffraction Patterns of Extended Superconductor-Topological Insulator-Superconductor Josephson Junctions Open
In an extended superconductor-topological insulator-superconductor (S-TI-S) Josephson junction in a magnetic field, localized Majorana bound states (MBS) are predicted to exist at the cores of Josephson vortices where the local phase diffe…
View article: REC domain stabilizes the active heptamer of σ54-dependent transcription factor, FleR from Pseudomonas aeruginosa
REC domain stabilizes the active heptamer of σ54-dependent transcription factor, FleR from Pseudomonas aeruginosa Open
Motility in Pseudomonas aeruginosa is mediated through a single, polar flagellum, which is essential for virulence, colonization, and biofilm formation. FleSR, a two-component system (TCS), serves as a critical checkpoint in flagellar asse…
View article: Erratum: Mutation of putative glycosyl transferases PslC and PslI confers susceptibility to antibiotics and leads to drastic reduction in biofilm formation in Pseudomonas aeruginosa
Erratum: Mutation of putative glycosyl transferases PslC and PslI confers susceptibility to antibiotics and leads to drastic reduction in biofilm formation in Pseudomonas aeruginosa Open
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our princi…
View article: Mutation of putative glycosyl transferases PslC and PslI confers susceptibility to antibiotics and leads to drastic reduction in biofilm formation in Pseudomonas aeruginosa
Mutation of putative glycosyl transferases PslC and PslI confers susceptibility to antibiotics and leads to drastic reduction in biofilm formation in Pseudomonas aeruginosa Open
Pseudomonas aeruginosa is an opportunistic, multidrug-resistant pathogen capable of adapting to numerous environmental conditions and causing fatal infections in immunocompromised patients. The predominant lifestyle of P. aeruginosa is in …
View article: Structural analysis of novel drug targets for mitigation of <i>Pseudomonas aeruginosa</i> biofilms
Structural analysis of novel drug targets for mitigation of <i>Pseudomonas aeruginosa</i> biofilms Open
Pseudomonas aeruginosa is an opportunistic human pathogen responsible for acute and chronic, hard to treat infections. Persistence of P. aeruginosa is due to its ability to develop into biofilms, which are sessile bacterial communities adh…
View article: High temperature, gate-free quantum anomalous Hall effect with an active capping layer
High temperature, gate-free quantum anomalous Hall effect with an active capping layer Open
Quantum anomalous Hall effect (QAHE) was discovered a decade ago, but is still not utilized beyond a handful of research groups, due to numerous limitations such as extremely low temperature, electric field-effect gating requirement, small…