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View article: Proof of concept: real-time viability and metabolic profiling of probiotics with isothermal microcalorimetry
Proof of concept: real-time viability and metabolic profiling of probiotics with isothermal microcalorimetry Open
Isothermal microcalorimetry (IMC) is a potent analytical method for the real-time assessment of microbial metabolic activity, which serves as an indicator of microbial viability. This approach is highly relevant to the fields of probiotics…
View article: Epigenetics and chromatin structure regulate var2csa expression and the placental binding phenotype in Plasmodium falciparum
Epigenetics and chromatin structure regulate var2csa expression and the placental binding phenotype in Plasmodium falciparum Open
Plasmodium falciparum is responsible for what appears to be a never-ending public health issue in the developing world. With repeated infections, a gradual semi-immunity to severe malaria can be acquired but this is disrupted when women be…
View article: Epigenetics and chromatin structure regulate var2csa expression and the placental binding phenotype in Plasmodium falciparum
Epigenetics and chromatin structure regulate var2csa expression and the placental binding phenotype in Plasmodium falciparum Open
Plasmodium falciparum is responsible for what appears to be a never-ending public health issue in the developing world. With repeated infections, a gradual semi-immunity to severe malaria can be acquired but this is disrupted when women be…
View article: Epigenetics and chromatin structure regulate <i>var2csa</i> expression and the placental binding phenotype in <i>Plasmodium falciparum</i>
Epigenetics and chromatin structure regulate <i>var2csa</i> expression and the placental binding phenotype in <i>Plasmodium falciparum</i> Open
Plasmodium falciparum is responsible for what appears to be a never-ending public health issue in the developing world. With repeated infections, a gradual semi-immunity to severe malaria can be acquired but this is disrupted when women be…
View article: GPR43 regulates marginal zone B‐cell responses to foreign and endogenous antigens
GPR43 regulates marginal zone B‐cell responses to foreign and endogenous antigens Open
Marginal zone (MZ) B cells are innate‐like B cells that produce polyreactive antibodies with an affinity for microbial molecular patterns and carbohydrate ligands. MZ B cells have been shown to be important in mediating immunity to various…
View article: Epitopes of anti-RIFIN antibodies and characterization of rif-expressing Plasmodium falciparum parasites by RNA sequencing
Epitopes of anti-RIFIN antibodies and characterization of rif-expressing Plasmodium falciparum parasites by RNA sequencing Open
Variable surface antigens of Plasmodium falciparum have been a major research focus since they facilitate parasite sequestration and give rise to deadly malaria complications. Coupled with its potential use as a vaccine candidate, the rece…