Mae J. Ciancio
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View article: Performance-Enhancing Effects of Inhaled Medications: Implications for Heart, Muscle Function, and Doping Detection in Athletes
Performance-Enhancing Effects of Inhaled Medications: Implications for Heart, Muscle Function, and Doping Detection in Athletes Open
Inhaled medications, commonly prescribed for respiratory conditions such as asthma and exercise-induced bronchoconstriction, are increasingly scrutinized in sports medicine due to their potential performance-enhancing effects. Bronchodilat…
View article: Current and Emerging Roles of GLP1 Receptor Agonists Across the Spectrum of Left Ventricular Ejection Fraction in Heart Failure
Current and Emerging Roles of GLP1 Receptor Agonists Across the Spectrum of Left Ventricular Ejection Fraction in Heart Failure Open
Glucagon-like peptide-1 receptor agonists (GLP1-RAs) have demonstrated significant cardiometabolic benefits, particularly in patients with type 2 diabetes and obesity. Their role in heart failure (HF) is gaining increasing attention, with …
View article: Advancements in Sensor Technology for Monitoring and Management of Chronic Coronary Syndrome
Advancements in Sensor Technology for Monitoring and Management of Chronic Coronary Syndrome Open
Chronic Coronary Syndrome (CCS) significantly impacts quality of life and increases the risk of adverse cardiovascular events, remaining the leading cause of mortality worldwide. The use of sensor technology in medicine is emerging as a pr…
View article: Exploring the Role of Genetic and Genomic Factors in Therapeutic Response to Heart Failure: A Comprehensive Analytical Review
Exploring the Role of Genetic and Genomic Factors in Therapeutic Response to Heart Failure: A Comprehensive Analytical Review Open
Heart failure (HF) remains a leading cause of morbidity and mortality worldwide. Despite significant advances in pharmacological therapies, responses to treatment vary widely among patients. Growing evidence suggests that genetic factors p…
View article: The Microbiome of an Outpatient Sports Medicine Clinic During a Global Pandemic: Effects of Implementation of a Microbiome-Specific Cleaning Program
The Microbiome of an Outpatient Sports Medicine Clinic During a Global Pandemic: Effects of Implementation of a Microbiome-Specific Cleaning Program Open
Outpatient healthcare facilities represent potential sources of healthcare-associated infections (HAIs). The purpose of this study was to survey high-contact surfaces in an outpatient physical therapy clinic, characterize the microbiome of…
View article: Tailoring Pharmacological Treatment in Cardiogenic Shock: A Narrative Review
Tailoring Pharmacological Treatment in Cardiogenic Shock: A Narrative Review Open
Cardiogenic shock (CS) is a critical condition marked by end-organ hypoperfusion and sustained hypotension, necessitating the use of inotropic or vasoactive agents for hemodynamic support. It is the leading cause of mortality in patients w…
View article: The Complementary Role of Cardiopulmonary Exercise Testing in Coronary Artery Disease: From Early Diagnosis to Tailored Management
The Complementary Role of Cardiopulmonary Exercise Testing in Coronary Artery Disease: From Early Diagnosis to Tailored Management Open
Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, accounting for over 9 million deaths annually. The prevalence of CAD continues to rise, driven by ageing and the increasing prevalence of risk fact…
View article: The microbiome of an outpatient rehabilitation clinic and predictors of contamination: A pilot study
The microbiome of an outpatient rehabilitation clinic and predictors of contamination: A pilot study Open
Background Understanding sources of microbial contamination in outpatient rehabilitation (REHAB) clinics is important to patients and healthcare providers. Purpose The purpose of this study was to characterize the microbiome of an outpatie…
View article: Fat and exposure to 4-nitroquinoline-1-oxide causes histologic and inflammatory changes in murine livers
Fat and exposure to 4-nitroquinoline-1-oxide causes histologic and inflammatory changes in murine livers Open
Risk factors for liver cancer include tobacco use, alcohol consumption, obesity, and male sex. Administration of 4-nitroquinonline-1-oxide (4NQO) in drinking water mimics the effects of tobacco and leads to oral carcinoma in mice. This stu…
View article: Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice
Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice Open
Objective One-carbon metabolism is a metabolic network that integrates nutritional signals with biosynthesis, redox homeostasis, and epigenetics. There are sex differences in hepatic one-carbon metabolism. However, it is unclear whether th…
View article: Selective Regional Alteration of the Gut Microbiota by Diet and Antibiotics
Selective Regional Alteration of the Gut Microbiota by Diet and Antibiotics Open
The small intestinal microbiota has recently been implicated in contributing to metabolic disease. We previously demonstrated that diets rich in saturated milk fat have a particularly strong impact on the small bowel microbiota as opposed …
View article: Effectiveness of an Interprofessional Education Event for Graduate Health Professional Students
Effectiveness of an Interprofessional Education Event for Graduate Health Professional Students Open
Purpose: The purpose of this study was to investigate the impact of a single, optional, half-day, interprofessional education (IPE) event for a myriad of graduate-level health professional students (n=44) at a university in Illinois, USA. …