Magdalena Zaucha
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View article: Differential Regulation of TCR‐Induced ZFP36 and ZFP36L1 Expression by Cyclosporin A in CD8 <sup>+</sup> T Cells
Differential Regulation of TCR‐Induced ZFP36 and ZFP36L1 Expression by Cyclosporin A in CD8 <sup>+</sup> T Cells Open
CD8 + T cells target infected or malignant cells via the production of pro‐inflammatory cytokines and direct target cell killing. Members of the ZFP36‐family of RNA‐binding proteins, ZFP36 and ZFP36L1, regulate these functions in T cells v…
View article: Gut microbiota: a new factor modulating the immunizing potential of viral and cancer vaccines
Gut microbiota: a new factor modulating the immunizing potential of viral and cancer vaccines Open
View article: RIG-I-like receptor-dependent type I Interferon regulates antigen dose and activation in yellow fever vaccine 17D-infected antigen presenting cells
RIG-I-like receptor-dependent type I Interferon regulates antigen dose and activation in yellow fever vaccine 17D-infected antigen presenting cells Open
The live-attenuated yellow fever vaccine 17D-204 (YF17D) activates robust innate immune responses followed by rapid induction of adaptive immunity resulting in long-lasting protection. YF17D triggers the production of type I interferons (I…
View article: Differential regulation of TCR-induced ZFP36 and ZFP36L1 expression by cyclosporin A in CD8+ T cells
Differential regulation of TCR-induced ZFP36 and ZFP36L1 expression by cyclosporin A in CD8+ T cells Open
CD8+ T cells target infected or malignant cells via the production of pro-inflammatory cytokines and direct target cell killing. Members of the ZFP36-family of RNA binding proteins, ZFP36 and ZFP36L1 regulate these functions in T cells via…
View article: Interferon-induced activation of dendritic cells and monocytes by yellow fever vaccination correlates with early antibody responses
Interferon-induced activation of dendritic cells and monocytes by yellow fever vaccination correlates with early antibody responses Open
Yellow fever vaccination provides long-lasting protection and is a unique model for studying the immune response to an acute RNA virus infection in humans. To elucidate the early innate immune events preceding the rapid generation of prote…
View article: Basal T cell activation predicts yellow fever vaccine response independently of cytomegalovirus infection and sex-related immune variations
Basal T cell activation predicts yellow fever vaccine response independently of cytomegalovirus infection and sex-related immune variations Open
View article: Interferon-induced activation state of circulating dendritic cells and monocytes triggered by yellow fever vaccination correlates with early protective antibody responses
Interferon-induced activation state of circulating dendritic cells and monocytes triggered by yellow fever vaccination correlates with early protective antibody responses Open
Yellow fever vaccination provides long-lasting protection and is a unique model for studying the immune response to an acute RNA virus infection in humans. To elucidate the early innate immune events preceding the rapid generation of prote…
View article: Prior flavivirus immunity skews the yellow fever vaccine response to cross-reactive antibodies with potential to enhance dengue virus infection
Prior flavivirus immunity skews the yellow fever vaccine response to cross-reactive antibodies with potential to enhance dengue virus infection Open
View article: Prior flavivirus immunity skews the yellow fever vaccine response to expand cross-reactive antibodies with increased risk of antibody dependent enhancement of Zika and dengue virus infection
Prior flavivirus immunity skews the yellow fever vaccine response to expand cross-reactive antibodies with increased risk of antibody dependent enhancement of Zika and dengue virus infection Open
Human pathogenic flaviviruses pose a significant health concern and vaccination is the most effective instrument to control their circulation. How pre-existing immunity to antigenically related viruses modulates immunization outcome remain…
View article: FluoRNT: A robust, efficient assay for the detection of neutralising antibodies against yellow fever virus 17D
FluoRNT: A robust, efficient assay for the detection of neutralising antibodies against yellow fever virus 17D Open
There is an urgent need for better diagnostic and analytical methods for vaccine research and infection control in virology. This has been highlighted by recently emerging viral epidemics and pandemics (Zika, SARS-CoV-2), and recurring vir…
View article: Dynamic changes in circulating T follicular helper cell composition predict neutralising antibody responses after yellow fever vaccination
Dynamic changes in circulating T follicular helper cell composition predict neutralising antibody responses after yellow fever vaccination Open
Objectives T follicular helper (Tfh) cells are the principal T helper cell subset that provides help to B cells for potent antibody responses against various pathogens. In this study, we took advantage of the live‐attenuated yellow fever v…