Magdalene C. Jawahar
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View article: Using Multi-Omic Signatures in the Understanding of Inflammation and Psychosis: Can Methylation-Derived White Blood Cell Proportions Guide Early Intervention?
Using Multi-Omic Signatures in the Understanding of Inflammation and Psychosis: Can Methylation-Derived White Blood Cell Proportions Guide Early Intervention? Open
View article: Pre-COVID life expectancy, mortality, and burden of diseases for adults 70 years and older in Australia: a systematic analysis for the Global Burden of Disease 2019 Study
Pre-COVID life expectancy, mortality, and burden of diseases for adults 70 years and older in Australia: a systematic analysis for the Global Burden of Disease 2019 Study Open
View article: Dotting the I's and crossing the T's: A South Australian perspective on variability in troponin thresholds for myocarditis risk in clozapine treatment
Dotting the I's and crossing the T's: A South Australian perspective on variability in troponin thresholds for myocarditis risk in clozapine treatment Open
View article: General intelligence and executive functioning are overlapping but separable at genetic and molecular pathway levels: An analytical review of existing GWAS findings
General intelligence and executive functioning are overlapping but separable at genetic and molecular pathway levels: An analytical review of existing GWAS findings Open
Understanding the genomic architecture and molecular mechanisms of cognitive functioning in healthy individuals is critical for developing tailored interventions to enhance cognitive functioning, as well as for identifying targets for trea…
View article: Genome-wide association study of circulating interleukin 6 levels identifies novel loci
Genome-wide association study of circulating interleukin 6 levels identifies novel loci Open
Interleukin 6 (IL-6) is a multifunctional cytokine with both pro- and anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex di…
View article: Genome-wide association study of circulating interleukin 6 levels identifies novel loci
Genome-wide association study of circulating interleukin 6 levels identifies novel loci Open
Interleukin 6 (IL-6) is a multifunctional cytokine with both pro- and anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex di…
View article: Short-Term Environmental Enrichment is a Stronger Modulator of Brain Glial Cells and Cervical Lymph Node T Cell Subtypes than Exercise or Combined Exercise and Enrichment
Short-Term Environmental Enrichment is a Stronger Modulator of Brain Glial Cells and Cervical Lymph Node T Cell Subtypes than Exercise or Combined Exercise and Enrichment Open
View article: Duration of Environmental Enrichment Determines Astrocyte Number and Cervical Lymph Node T Lymphocyte Proportions but Not the Microglial Number in Middle-Aged C57BL/6 Mice
Duration of Environmental Enrichment Determines Astrocyte Number and Cervical Lymph Node T Lymphocyte Proportions but Not the Microglial Number in Middle-Aged C57BL/6 Mice Open
Environmental enrichment (EE) has been shown to modulate behavior and immunity. We recently reported that both short and long-term EE enhance baseline locomotion and alleviate depressive-like behavior, but only long-term EE affects locomot…
View article: Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression
Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression Open
View article: Short-term environmental enrichment, and not physical exercise, alleviate cognitive decline and anxiety from middle age onwards without affecting hippocampal gene expression
Short-term environmental enrichment, and not physical exercise, alleviate cognitive decline and anxiety from middle age onwards without affecting hippocampal gene expression Open
View article: The PHF21B gene is associated with major depression and modulates the stress response
The PHF21B gene is associated with major depression and modulates the stress response Open
Major depressive disorder (MDD) affects around 350 million people worldwide; however, the underlying genetic basis remains largely unknown. In this study, we took into account that MDD is a gene-environment disorder, in which stress is a c…
View article: Epigenetic alterations following early postnatal stress: a review on novel aetiological mechanisms of common psychiatric disorders
Epigenetic alterations following early postnatal stress: a review on novel aetiological mechanisms of common psychiatric disorders Open
Stressor exposure during early life has the potential to increase an individual's susceptibility to a number of neuropsychiatric conditions such as mood and anxiety disorders and schizophrenia in adulthood. This occurs in part due to the d…