Maha Abdullah
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View article: Exploring the synthesis and biomedical potential of banana stem fiber for antimicrobial and wound healing applications
Exploring the synthesis and biomedical potential of banana stem fiber for antimicrobial and wound healing applications Open
Need for non-toxic materials especially for biomedical application remains the most important driving force for the discovery of nature-derived biomaterials. In particular, fibers and extracts from plants with medicinal value are vastly in…
View article: Review on Plant-Based Management in Combating Antimicrobial Resistance - Mechanistic Perspective
Review on Plant-Based Management in Combating Antimicrobial Resistance - Mechanistic Perspective Open
Antimicrobial resistance (AMR) occurs when microbes no longer respond to any pharmacological agents, rendering the conventional antimicrobial agents ineffective. AMR has been classified as one of the top 10 life-threatening global health p…
View article: Evaluation of Circulating MicroRNAs and Adipokines in Breast Cancer Survivors with Arm Lymphedema
Evaluation of Circulating MicroRNAs and Adipokines in Breast Cancer Survivors with Arm Lymphedema Open
Breast cancer-related lymphedema (BCRL) is a form of secondary lymphedema that is characterized by abnormal swelling of one or both arms due to the accumulation of lymph fluid in the interstitial tissue spaces, resulting from obstruction o…
View article: Exploration of biomarkers for the diagnosis, treatment and prognosis of cervical cancer: a review
Exploration of biomarkers for the diagnosis, treatment and prognosis of cervical cancer: a review Open
As the fourth most diagnosed cancer, cervical cancer (CC) is one of the major causes of cancer-related mortality affecting females globally, particularly when diagnosed at advanced stage. Discoveries of CC biomarkers pave the road to preci…
View article: Expression of Killer Cell Immunoglobulin-like Receptors (KIR) in Sex-associated Malignancies
Expression of Killer Cell Immunoglobulin-like Receptors (KIR) in Sex-associated Malignancies Open
Introduction: Sex shapes immune response with possible consequence on tumor immune escape. Acute lymphoblastic leukemia (ALL) predominates in males while ovarian cancer (OC) occurs in females. NK cells essential for tumor killing may have …
View article: Editorial: Differential Efficacy of Immune Checkpoint Inhibitors due to Age and Sex Factors
Editorial: Differential Efficacy of Immune Checkpoint Inhibitors due to Age and Sex Factors Open
EDITORIAL article Front. Immunol., 16 June 2022Sec. Cytokines and Soluble Mediators in Immunity Volume 13 - 2022 | https://doi.org/10.3389/fimmu.2022.941254
View article: Differential Regulation of NK Cell Receptors in Acute Lymphoblastic Leukemia
Differential Regulation of NK Cell Receptors in Acute Lymphoblastic Leukemia Open
Cancer immunotherapies are preferred over conventional treatments which are highly cytotoxic to normal cells. Focus has been on T cells but natural killer (NK) cells have equal potential. Concepts in cancer control and influence of sex req…
View article: Alpha-2-macroglobulin, an infection resistant biomarker in Epinephelus fuscoguttatus (Forsskål, 1775)
Alpha-2-macroglobulin, an infection resistant biomarker in Epinephelus fuscoguttatus (Forsskål, 1775) Open
Data availability
View article: Inverse influence of HLA-DR7, DR12 and DR13 on the pathogenesis of Der p 1-induced allergic rhinitis
Inverse influence of HLA-DR7, DR12 and DR13 on the pathogenesis of Der p 1-induced allergic rhinitis Open
Supplementary tables and figures from the yet to be published study entitled "Inverse influence of HLA-DR7, DR12 and DR13 on the pathogenesis of Der p 1-induced allergic rhinitis".
View article: Inverse influence of HLA-DR7, DR12 and DR13 on the pathogenesis of Der p 1-induced allergic rhinitis
Inverse influence of HLA-DR7, DR12 and DR13 on the pathogenesis of Der p 1-induced allergic rhinitis Open
Supplementary tables and figures from the yet to be published study entitled "Inverse influence of HLA-DR7, DR12 and DR13 on the pathogenesis of Der p 1-induced allergic rhinitis".
View article: TAT Κappa (TATΚ): A Novel Cell Penetrating Peptide for Delivery of Pluripotent Proteins into Target Cells
TAT Κappa (TATΚ): A Novel Cell Penetrating Peptide for Delivery of Pluripotent Proteins into Target Cells Open
Induced pluripotent stem cell (iPSC) holds a magnificent place in the medical revolution. Its emergence is expected to instigate development of novel therapies for regenerative medicine and treatment of malignant diseases. Moreover, iPSC u…
View article: Human leucocyte antigens profiling in Malay female patients with systemic lupus erythematosus: are we the same or different?
Human leucocyte antigens profiling in Malay female patients with systemic lupus erythematosus: are we the same or different? Open
Objective SLE is a heterogeneous autoimmune disease, in terms of clinical presentation, incidence and severity across diverse ethnic populations. We investigated the human leucocyte antigens (HLA) profile (ie, HLA-A, HLA-B and HLA-C, HLA-D…
View article: Alpha-2-macroglobulin, an infection resistant biomarker in Epinephelus fuscoguttatus (Forsskål, 1775)
Alpha-2-macroglobulin, an infection resistant biomarker in Epinephelus fuscoguttatus (Forsskål, 1775) Open
Data availability
View article: Recent Updates on Mechanisms of Resistance to 5-Fluorouracil and Reversal Strategies in Colon Cancer Treatment
Recent Updates on Mechanisms of Resistance to 5-Fluorouracil and Reversal Strategies in Colon Cancer Treatment Open
5-Fluorouracil (5-FU) plus leucovorin (LV) remain as the mainstay standard adjuvant chemotherapy treatment for early stage colon cancer, and the preferred first-line option for metastatic colon cancer patients in combination with oxaliplat…
View article: Assessment of Potential Risk Factors and Skin Ultrasound Presentation Associated with Breast Cancer-Related Lymphedema in Long-Term Breast Cancer Survivors
Assessment of Potential Risk Factors and Skin Ultrasound Presentation Associated with Breast Cancer-Related Lymphedema in Long-Term Breast Cancer Survivors Open
Breast cancer has been reported to have the highest survival rate among various cancers. However, breast cancer survivors face several challenges following breast cancer treatment including breast cancer-related lymphedema (BCRL), sexual d…
View article: Cross-Cultural Adaptation of the Functional Assessment of Cancer Therapy-Breast (FACT-B) in Malaysian Breast Cancer Survivors
Cross-Cultural Adaptation of the Functional Assessment of Cancer Therapy-Breast (FACT-B) in Malaysian Breast Cancer Survivors Open
The Malay version of the FACT-B demonstrated reliable properties and is effective in assessing QOL and can be applied in Malaysian breast cancer survivors.
View article: HLA-DRB1*04 as a Risk Allele to Systemic Lupus Erythematosus and Lupus Nephritis in the Malay Population of Malaysia
HLA-DRB1*04 as a Risk Allele to Systemic Lupus Erythematosus and Lupus Nephritis in the Malay Population of Malaysia Open
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease afflicting multiple organs. Lupus nephritis (LN) is a serious complication of SLE and remains a major cause of mortality and morbidity. Curative therapy remains unavailable…
View article: Mycobiome in the Gut: A Multiperspective Review
Mycobiome in the Gut: A Multiperspective Review Open
Human gut is home to a diverse and complex microbial ecosystem encompassing bacteria, viruses, parasites, fungi, and other microorganisms that have an undisputable role in maintaining good health for the host. Studies on the interplay betw…
View article: Elevated interleukin-25 and its association to Th2 cytokines in systemic lupus erythematosus with lupus nephritis
Elevated interleukin-25 and its association to Th2 cytokines in systemic lupus erythematosus with lupus nephritis Open
Systemic lupus erythematosus (SLE) is an autoimmune disorder that is associated with lupus nephritis, initiated by the deposition of immune complexes in the kidney; subsequently, this induces the overexpression of cytokines. Lupus nephriti…
View article: Recovery of recombinant Mycobacterium tuberculosis antigens fused with cell wall-anchoring motif (LysM) from inclusion bodies using non-denaturing reagent (N-laurylsarcosine)
Recovery of recombinant Mycobacterium tuberculosis antigens fused with cell wall-anchoring motif (LysM) from inclusion bodies using non-denaturing reagent (N-laurylsarcosine) Open
The presented NLS purification strategy enables an efficient and rapid method for obtaining higher yields of soluble cell wall-anchoring Mycobacterium tuberculosis antigens-LysM fusion proteins from IBs in E. coli.
View article: Latent tuberculosis infection among medical students in Malaysia
Latent tuberculosis infection among medical students in Malaysia Open
Objective: This study aimed to determine prevalence of latent tuberculosis infection among medical students and tuberculosis exposure at the health facilities. Methods: A cross-section of study year 1 (n=68) and year 5 (n=75) medical stude…
View article: Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice Open
View article: Immunity, feed, and husbandry in fish health management of cultured Epinephelus fuscoguttatus with reference to Epinephelus coioides
Immunity, feed, and husbandry in fish health management of cultured Epinephelus fuscoguttatus with reference to Epinephelus coioides Open
Groupers are dispersed worldwide in the tropical and subtropical waters. They are prized in the live reef fish trade, making them candidates with high market value and consumer demand. In the Asian-Pacific region, the brown-marbled grouper…
View article: Additional file 3: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Additional file 3: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice Open
Table S3. Data set from ELISA for time-course of the serum total IgG antibody response against Lp ACERL, Lp ACERL/LcIL-12, ACERL, LcIL-12, Lp and PBS immunization. (XLSX 16 kb)
View article: Additional file 6: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Additional file 6: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice Open
Table S6. Data set from cytokine response profiling of GIT for IFN-Îł (pg/ml), IL-4 (pg/ml), IL-2 (pg/ml), IL-6 (pg/ml), IL-12 (pg/ml) and TNF-Îą (pg/ml). (XLSX 148 kb)
View article: Additional file 7: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Additional file 7: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice Open
Table S7. Data set from cytokine response profiling of re-stimulated splenocytes with ACERL antigen after 48Â h for IFN-Îł (pg/ml), IL-4 (pg/ml), IL-2 (pg/ml), IL-6 (pg/ml), IL-12 (pg/ml) and TNF-Îą (pg/ml). (XLSX 41 kb)
View article: Additional file 4: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Additional file 4: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice Open
Table S4. Data set from cytokine response profiling of spleen for IFN-Îł (pg/ml), IL-4 (pg/ml), IL-2 (pg/ml), IL-6 (pg/ml), IL-12 (pg/ml) and TNF-Îą (pg/ml). (XLSX 47 kb)
View article: Additional file 2: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Additional file 2: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice Open
Table S2. Data set of whole cell ELISA of L. plantarum attached with ACERL for a four-day period. (XLSX 13 kb)
View article: Additional file 1: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Additional file 1: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice Open
Table S1. Data set of L. plantarum Pa21 carrying ACERL antigen growth profiles. (XLSX 25 kb)
View article: Additional file 5: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Additional file 5: of Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice Open
Table S5. Data set from cytokine response profiling of lung for IFN-Îł (pg/ml), IL-4 (pg/ml), IL-2 (pg/ml), IL-6 (pg/ml), IL-12 (pg/ml) and TNF-Îą (pg/ml). (XLSX 37 kb)