Maha Fadel
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View article: Impact of the antifungal and antioxidant potential of monoterpenoids on the paper manuscripts with iron gall ink
Impact of the antifungal and antioxidant potential of monoterpenoids on the paper manuscripts with iron gall ink Open
View article: Protection of paper manuscripts by antimicrobial polyphenolic compounds from fungal extracts and antioxidant nanoparticles
Protection of paper manuscripts by antimicrobial polyphenolic compounds from fungal extracts and antioxidant nanoparticles Open
This study describes a novel method for protecting paper manuscripts with antifungal and antioxidant compounds. Polyphenolic compounds, such as methyl gallate, and nanoparticles like cerium oxide nanoparticles (CeO 2 NPs) were used. These …
View article: In vitro Antimicrobial Photodynamic Activity of Tecoma stans Yellow Flowers Extract Loaded in Nano-Emulsion
In vitro Antimicrobial Photodynamic Activity of Tecoma stans Yellow Flowers Extract Loaded in Nano-Emulsion Open
View article: Antimicrobial photodynamic inactivation and photosensitizers: A succinct review
Antimicrobial photodynamic inactivation and photosensitizers: A succinct review Open
View article: Multiple resistant plane warts successfully treated by photodynamic therapy mediated by transfersomal Methylene blue gel: A case report
Multiple resistant plane warts successfully treated by photodynamic therapy mediated by transfersomal Methylene blue gel: A case report Open
View article: New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats
New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats Open
Cellulite (CLT) is one of the commonly known lipodystrophy syndromes affecting post-adolescent women worldwide. It is topographically characterized by an orange-peel, dimpled skin appearance hence, it is an unacceptable cosmetic problem. C…
View article: Aluminum phthalocyanine tetrasulfonate conjugated to surface-modified Iron oxide nanoparticles as a magnetic targeting platform for photodynamic therapy of Ehrlich tumor-bearing mice
Aluminum phthalocyanine tetrasulfonate conjugated to surface-modified Iron oxide nanoparticles as a magnetic targeting platform for photodynamic therapy of Ehrlich tumor-bearing mice Open
PDT mediated by magnetic targeting significantly inhibited tumor growth with minimal adverse effects, indicating its great potential as a promising strategy for solid cancer treatment.
View article: Nano-Liposomal Beetroot Phyto-Pigment in Photodynamic Therapy as a Prospective Green Approach for Cancer Management: In Vitro Evaluation and Molecular Dynamic Simulation
Nano-Liposomal Beetroot Phyto-Pigment in Photodynamic Therapy as a Prospective Green Approach for Cancer Management: In Vitro Evaluation and Molecular Dynamic Simulation Open
Using plant extracts as photosensitizers in photodynamic therapy (PDT) represents a significant green approach toward sustainability. This study investigates beetroot juice (BRJ), betanin, and their liposomal formulations (Lip-BRJ, Lip-Bet…
View article: Topical Photodynamic Therapy Mediated with Hematoporphyrin-HCl using Glycerin as Penetrating Enhancer: In vitro and in vivo studies
Topical Photodynamic Therapy Mediated with Hematoporphyrin-HCl using Glycerin as Penetrating Enhancer: In vitro and in vivo studies Open
View article: REMOVAL OF PRESSURE SENSITIVE TAPES FROM VINTAGE SILVER GELATIN PRINTS USING SELECTED GEL-BASED SYSTEMS: AN EXPERIMENTAL STUDY
REMOVAL OF PRESSURE SENSITIVE TAPES FROM VINTAGE SILVER GELATIN PRINTS USING SELECTED GEL-BASED SYSTEMS: AN EXPERIMENTAL STUDY Open
Historical photographs play a significant role as records, documenting the various stages of the history of Egypt and reflecting our identity and social, cultural, and religious values. Silver gelatin prints were the dominant positive prin…
View article: Parents’ Knowledge and Attitude Regarding Dyslexia: Cross-Sectional Survey
Parents’ Knowledge and Attitude Regarding Dyslexia: Cross-Sectional Survey Open
Background: Dyslexia is a vague hidden disorder that interferes with children's learning process.Parents are the primary caregivers for their children and have a great influence on their children's academic success.Unfortunately, the major…
View article: Magnetic fluid hyperthermia controlled by frequency counter and colorimetric program systems based on magnetic nanoparticles
Magnetic fluid hyperthermia controlled by frequency counter and colorimetric program systems based on magnetic nanoparticles Open
Magnetic nanoparticles (MNP) are anticipated to perform better in terms of thermal conductivity when exposed to alternating magnetic fields (AMF). Herein, key parameters for efficient heating are examined in an AMF that is organized and ma…
View article: Evaluation of the role of hydroxychloroquine as a lipid profile improving and glucose adjusting drug in Egyptian females with inactive rheumatoid arthritis
Evaluation of the role of hydroxychloroquine as a lipid profile improving and glucose adjusting drug in Egyptian females with inactive rheumatoid arthritis Open
Background/aim Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease that leads to joint destruction and disability with increased risk of cardiovascular disease (CVD), a leading cause of morbidity and mortality in RA. Modif…
View article: Dual antineoplastic and photodynamic effects of methanolic extract of <i>Tecoma stans</i> yellow flowers for cancer treatment
Dual antineoplastic and photodynamic effects of methanolic extract of <i>Tecoma stans</i> yellow flowers for cancer treatment Open
Introduction: Tecoma stans is a fast-growing plant from the family Bignoniaceae. Various parts of T. stans have been used in different biological applications, especially in cancer treatment. Photodynamic therapy (PDT) is a promising modal…
View article: Self-assembled surfactant-based nanoparticles as a platform for solubilization and enhancement of the photothermal activity of sepia melanin
Self-assembled surfactant-based nanoparticles as a platform for solubilization and enhancement of the photothermal activity of sepia melanin Open
Background Sepia melanin (SM) is a natural photothermal biopolymer. Its biomedical applications are limited due to its poor solubility and bioavailability. This study aims to prepare a soluble formulation of sepia melanin to enhance its so…
View article: A Novel Biocompatibility Docetaxel Loaded with Magnetic Nanoparticles for Cancer Therapy
A Novel Biocompatibility Docetaxel Loaded with Magnetic Nanoparticles for Cancer Therapy Open
View article: Reviewing the reported pharmacognostic and pharmacological investigations on <i>Tecoma stans</i> Juss. ex Kunth
Reviewing the reported pharmacognostic and pharmacological investigations on <i>Tecoma stans</i> Juss. ex Kunth Open
This review is destined for a comprehensive assessment of the phytochemistry and medicinal properties of Tecoma stans, a widely used plant in folk cultures, as a traditionally safe and effective treatment for different diseases and complic…
View article: Nanotechnology and photodynamic therapy from a clinical perspective
Nanotechnology and photodynamic therapy from a clinical perspective Open
Photodynamic therapy (PDT) is currently applied clinically in many medical centers worldwide. The clinical outcomes are from one side satisfying and from the other side highlighting the areas of further development. Issues like hydrophobic…
View article: Serum beta2-microglobulin level in systemic lupus erythematosus patients: Relation to disease activity
Serum beta2-microglobulin level in systemic lupus erythematosus patients: Relation to disease activity Open
To assess the level of β2-microglubulin (β2M) in systemic lupus erythematosus (SLE) patients and its association with disease activity and other disease parameters. 40 SLE patients and 22 matched controls were studied. Serum β2M was assess…
View article: Gold-Polypyrrole-Loaded Eosin in Photo-Mediated Treatment of Hidradenitis Suppurativa: In Vivo Trans-Epidermal Permeation Study and Clinical Case Report
Gold-Polypyrrole-Loaded Eosin in Photo-Mediated Treatment of Hidradenitis Suppurativa: In Vivo Trans-Epidermal Permeation Study and Clinical Case Report Open
This study reports a new protocol for the management of Hidradenitis Suppurativa (HS), depending on the synergistic photodynamic and photothermal effect of eosin yellow-gold-polypyrrole hybrid nanoparticles (E-G-Ppy NPs). E-G-Ppy NPs and g…
View article: Transfersomal eosin topical delivery assisted by fractional CO2 laser for photodynamic treatment of palmar hyperhidrosis: case study
Transfersomal eosin topical delivery assisted by fractional CO2 laser for photodynamic treatment of palmar hyperhidrosis: case study Open
View article: (Rose Bengal)/(Eosin Yellow)-Gold-Polypyrrole Hybrids: A Design for Dual Photo-Active Nano-System with Ultra-High Loading Capacity
(Rose Bengal)/(Eosin Yellow)-Gold-Polypyrrole Hybrids: A Design for Dual Photo-Active Nano-System with Ultra-High Loading Capacity Open
Gold-polypyrrole nanoparticles represent an effective delivery system to improve the photodynamic and photothermal properties of RB and EY. The in situ one-pot synthesis method provided a means to greatly increase the loading capacity of A…
View article: (Rose Bengal)/(Eosin Yellow)-Gold-Polypyrrole Hybrids: A Design for Dual Photo-Active Nano-System with Ultra-High Loading Capacity
(Rose Bengal)/(Eosin Yellow)-Gold-Polypyrrole Hybrids: A Design for Dual Photo-Active Nano-System with Ultra-High Loading Capacity Open
Abdullah I El-Kholy,1 Doaa Abdel Fadeel,1 Maha Nasr,2 Ibrahim El-Sherbiny,3 Maha Fadel1 1Department of Medical Applications of Laser, Pharmaceutical Nano-Technology Unit, National Institute of Laser Enhanced Sciences (NILES), Cairo Univers…
View article: Preparation of avocado leaf simplicia macro/nano particles by using high energy ball mill
Preparation of avocado leaf simplicia macro/nano particles by using high energy ball mill Open
Taguchi method was used to examine high energy ball mill characteristics when producing micro/nano-particles of Simplicia powder using Orthogonal Array (OA) L25. Two factors and five levels were selected for the smallest diameter. The aver…
View article: Synthesis of Biocompatible and Environmentally Nanofibrous Mats Loaded with Moxifloxacin as a Model Drug for Biomedical Applications
Synthesis of Biocompatible and Environmentally Nanofibrous Mats Loaded with Moxifloxacin as a Model Drug for Biomedical Applications Open
Biopolymeric chitosan structure (Cs) is rationally investigated owing to its potentiality in pharmaceutical applications. The synthetic routes of biomimetic Cs-based blend electrospun nanofibers were studied. Herein, biocompatible crosslin…
View article: PEGylated lipid nanocarrier for enhancing photodynamic therapy of skin carcinoma using curcumin: in-vitro/in-vivo studies and histopathological examination
PEGylated lipid nanocarrier for enhancing photodynamic therapy of skin carcinoma using curcumin: in-vitro/in-vivo studies and histopathological examination Open
The use of (PEG)-grafted materials has a positive impact on drug delivery. In this study we designed PEGylated lipid nanocarriers (PLN) loaded with curcumin (Cur) to target skin cancer by photodynamic therapy. Cur is a polyphenolic compoun…
View article: Formulation and clinical evaluation of niosomal methylene blue for successful treatment of acne
Formulation and clinical evaluation of niosomal methylene blue for successful treatment of acne Open
Photodynamic therapy (PDT) can be defined as the administration of a nontoxic drug or dye known as Photosensitizer (PS) either systemically, locally, or topically to a patient bearing a lesion. Methylene blue considered as a photosensitize…
View article: <p>One-Step Synthesis of Polypyrrole-Coated Gold Nanoparticles for Use as a Photothermally Active Nano-System</p>
One-Step Synthesis of Polypyrrole-Coated Gold Nanoparticles for Use as a Photothermally Active Nano-System Open
This method simply and successfully synthesized AuPpy NPs nanoparticles that represent a safe alternative photothermally active multifunctional tool instead of highly toxic and non-biodegradable gold nanorods.
View article: One-Step Synthesis of Polypyrrole-Coated Gold Nanoparticles for Use as a Photothermally Active Nano-System
One-Step Synthesis of Polypyrrole-Coated Gold Nanoparticles for Use as a Photothermally Active Nano-System Open
Maha Fadel,1 Doaa Abdel Fadeel,1 Moustafa Ibrahim,2 Rania M Hathout,3 Abdullah I El-Kholy1 1Department of Medical Applications of Laser, Pharmaceutical Technology Unit, National Institute of Laser Enhanced Sciences (NILES), Cairo Universit…
View article: <p>Curcumin-loaded nanostructured lipid carriers prepared using Peceol™ and olive oil in photodynamic therapy: development and application in breast cancer cell line</p>
Curcumin-loaded nanostructured lipid carriers prepared using Peceol™ and olive oil in photodynamic therapy: development and application in breast cancer cell line Open
CUR loading in NLCs enhanced its cell penetration and cytotoxic anticancer properties both in dark and in light conditions.