Magda Sayed Mahmoud
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View article: Effect of Ashwagandha Roots on the Fertility of Diabetic Male Rats
Effect of Ashwagandha Roots on the Fertility of Diabetic Male Rats Open
View article: Coronary protection in TAVI: use of the guide catheter extension system
Coronary protection in TAVI: use of the guide catheter extension system Open
It was decided to perform transcatheter aortic valve implantation (TAVI) in an 82-year-old woman with severe aortic stenosis who had mitral and tricuspid mechanical prostheses, and no coronary lesions. Computed tomography showed an annulus…
View article: Clinical impact of IDH1 mutations and MGMT methylation in adult glioblastoma
Clinical impact of IDH1 mutations and MGMT methylation in adult glioblastoma Open
Background Impact of Isocitrate dehydrogenase1 ( IDH1 ) and O6-methylguanine-DNA methyltransferase ( MGMT ) in glioblastoma (GBM) have been of great interest due to their implications in prediction of prognosis of several types of cancer. …
View article: Clinical role of NDRG2-based methylation status on survival pattern of glioblastoma
Clinical role of NDRG2-based methylation status on survival pattern of glioblastoma Open
Objectives: Gliobalstoma is the most common primary brain tumor in adults with an extensive genetic and transcriptional heterogeneity, still identification of the role of DNA methylation, as one of epigenetic alterations, is emerged. Autho…
View article: Clinical Features of Germline Variations in Breast Cancer Patients Revealed by BRCA1 and BRCA2 Genes Using Next Generation Sequencing
Clinical Features of Germline Variations in Breast Cancer Patients Revealed by BRCA1 and BRCA2 Genes Using Next Generation Sequencing Open
Background. Breast cancer is among the most common female cancers worldwide according to WHO 2020 data. Breast cancer tumor suppressor genes (BRCA1 and BRCA2) are the most susceptibility genes for breast cancer. Thus, authors aimed to dete…
View article: Clinical Impact of IDH1 Mutations and MGMT Methylation in Adult Glioblastoma
Clinical Impact of IDH1 Mutations and MGMT Methylation in Adult Glioblastoma Open
Background. Genetic aberrations and epigenetic alterations have been reported in different types of cancer. Impact of Isocitrate dehydrogenase1 ( IDH1 ) and O6-methylguanine-DNAmethyltransferase ( MGMT ) in glioblastoma (GB) have been of g…
View article: Clinical Impact of <i>IDH1</i> Mutations and <i>MGMT</i> Methylation in Adult Glioblastoma Multiforme
Clinical Impact of <i>IDH1</i> Mutations and <i>MGMT</i> Methylation in Adult Glioblastoma Multiforme Open
Background Genetic aberrations and epigenetic alterations have been reported in different types of cancer. Impact of Isocitrate dehydrogenase1 ( IDH1 ) and O6-methylguanine-DNAmethyltransferase ( MGMT ) in glioblastoma multiforme (GBM) hav…
View article: Impact of circulating miRNA-373 on breast cancer diagnosis through targeting VEGF and cyclin D1 genes
Impact of circulating miRNA-373 on breast cancer diagnosis through targeting VEGF and cyclin D1 genes Open
Our results prove that miRNA-373, as an oncomir, would be a vital biomarker for BC diagnosis and prognosis by targeting both VEGF and cyclin D1.
View article: Diagnostic Role of Aberrant DNA Promoter Methylation in Ovarian Cancer
Diagnostic Role of Aberrant DNA Promoter Methylation in Ovarian Cancer Open
View article: Hepatitis C Virus as risk factor for development of hepatocellular carcinoma in Egypt: II-Enhancement role of matrix metalloproteinases-2 in dissemination of HCC
Hepatitis C Virus as risk factor for development of hepatocellular carcinoma in Egypt: II-Enhancement role of matrix metalloproteinases-2 in dissemination of HCC Open
Hepatitis C virus (HCV) infection is a major public health problem all over the world. Egypt has the highest prevalence of HCV worldwide (17-26%) with subsequent high morbidity from chronic liver disease, cirrhosis and hepatocellular carci…
View article: Aberrant methylation of <i>APC</i> and <i>RAR</i><i>β<sub>2</sub></i> genes in breast cancer patients
Aberrant methylation of <i>APC</i> and <i>RAR</i><i>β<sub>2</sub></i> genes in breast cancer patients Open
Changes in the status of DNA methylation are one of the most common molecular alterations in human neoplasia. We aimed to identify epigenetic molecular markers in serum for early detection of breast cancer. Authors analyzed retrospectively…