Mahdi Alemrajabi
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View article: Electronic patient-reported outcome systems and capabilities in cancer care: a systematic review
Electronic patient-reported outcome systems and capabilities in cancer care: a systematic review Open
Background Cancer care increasingly emphasizes patient-centred approaches, leading to the adoption of electronic patient-reported outcome (ePRO) systems for essential patient data collection. Our systematic review investigates the landscap…
View article: Solitary metastases of colon adenocarcinoma to the ankle: A case report and literature review
Solitary metastases of colon adenocarcinoma to the ankle: A case report and literature review Open
This case highlights a rare solitary metastatic pathway of CRC and underscores the importance of a comprehensive diagnostic work-up in patients with treatment-refractory bone disorders.
View article: The effect of total colectomy with posterior suture rectopexy in patients with internal prolapse and colonic inertia; A case series on 9 women
The effect of total colectomy with posterior suture rectopexy in patients with internal prolapse and colonic inertia; A case series on 9 women Open
This case series suggest the feasibility and advantages of performing total laparoscopic colectomy and laparoscopic posterior suture rectopexy in patients with IRP and colonic inertia, indicated for surgical correction of constipation. In …
View article: Dietary and circulating omega-6 fatty acids and their impact on cardiovascular disease, cancer risk, and mortality: a global meta-analysis of 150 cohorts and meta-regression
Dietary and circulating omega-6 fatty acids and their impact on cardiovascular disease, cancer risk, and mortality: a global meta-analysis of 150 cohorts and meta-regression Open
View article: Dietary Intakes of Omega-3, Omega-6 and Fiber and Risk of Rectal Cancer: A Case-Control Study
Dietary Intakes of Omega-3, Omega-6 and Fiber and Risk of Rectal Cancer: A Case-Control Study Open
Although no association between ω-3 and ω-6 intake was observed with the risk of RC, adequate daily intake of dietary fiber may protect us against RC risk.
View article: Clinical Analysis of Pyroptosis-Related Long Non-Coding RNAs MIAT and Gm15441 in Colorectal Cancer Patients with a History of Ulcerative Colitis
Clinical Analysis of Pyroptosis-Related Long Non-Coding RNAs MIAT and Gm15441 in Colorectal Cancer Patients with a History of Ulcerative Colitis Open
Dysregulated lncRNAs MIAT and Gm15441 in CRC can be more clinically important in cases of cancer related to UC due to their biological function in regulating the inflammation process, providing new ideas about the diagnosis and management …
View article: Advancing patient-centered cancer care: a systematic review of electronic patient-reported outcome measures
Advancing patient-centered cancer care: a systematic review of electronic patient-reported outcome measures Open
Background Electronic Patient-Reported Outcome Measures (ePROMs) have emerged as valuable tools in cancer care, facilitating the comprehensive assessment of patients’ physical, psychological, and social well-being. This study synthesizes l…
View article: The effects of FTO gene rs9939609 polymorphism on the association between colorectal cancer and dietary intake
The effects of FTO gene rs9939609 polymorphism on the association between colorectal cancer and dietary intake Open
Background FTO gene is associated with obesity, dietary intake, and the risk of colorectal cancer (CRC). In this study, patients with colorectal cancer were assessed for the interactions between FTO gene polymorphisms and dietary intake. M…
View article: Evaluation of long-term oncological outcomes of inter-sphincter resection compared with abdominoperineal resection for treatment of ultra-low rectal cancers: a single center 5-year experience
Evaluation of long-term oncological outcomes of inter-sphincter resection compared with abdominoperineal resection for treatment of ultra-low rectal cancers: a single center 5-year experience Open
There is no significant difference in the efficacy of the ISR method compared with the conventional APR for the treatment of ultra-low rectal cancer.
View article: THE ASSOCIATION BETWEEN COLORECTAL CANCER AND INDEX OF NUTRITIONAL QUALITY (INQ); A CASE-CONTROL STUDY
THE ASSOCIATION BETWEEN COLORECTAL CANCER AND INDEX OF NUTRITIONAL QUALITY (INQ); A CASE-CONTROL STUDY Open
Background: The nutritional quality of diet may influence the risk of colorectal cancer (CRC). This study compared the Index of Nutritional Quality (INQ) of various dietary components between colorectal cancer patients and healthy controls…
View article: Expanding CYLD protein in NF-κβ/TNF-α signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients
Expanding CYLD protein in NF-κβ/TNF-α signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients Open
Introduction: CYLD gene is a tumor suppressor, reducing in many cancers. Here, we aimed to investigate CYLD protein level and NF-κβ/TNF-α signaling pathway in rectal cancer patients with Lactobacillus acidophilus (L. acidophilus) consumpti…
View article: An evaluation of gastric adenocarcinoma-associated CircRNAs based on microarray meta-analysis and ceRNA networks
An evaluation of gastric adenocarcinoma-associated CircRNAs based on microarray meta-analysis and ceRNA networks Open
Gastric cancer is the fourth leading cause of cancer-related mortality and one of the most commonly diagnosed malignancies worldwide. Gastric adenocarcinoma (GAC) accounts for the majority of gastric cancer cases. Circular RNAs (circRNAs) …
View article: Incarceration of small bowel following percutaneous nephrostomy tube insertion
Incarceration of small bowel following percutaneous nephrostomy tube insertion Open
Percutaneous nephrostomy has become a well-established technique for providing permanent or temporary drainage of an obstructed urinary system for decades. Although it is generally considered a safe intervention, some complications might b…
View article: Simple mucopexy and hemorrhoidal arterial ligation with and without Doppler guide: a randomized clinical trial for short-term outcome
Simple mucopexy and hemorrhoidal arterial ligation with and without Doppler guide: a randomized clinical trial for short-term outcome Open
Purpose: Hemorrhoids are the most common benign anorectal diseases. Mucopexy strengthens the anal canal mucosa, which can be performed alone or in combination with Doppler-guided hemorrhoidal artery ligation (DG-HAL). In this study, we com…
View article: Evaluation of Long-term Oncological Outcomes of Inter-Sphincter Resection Compared with Traditional Abdominoperineal Resection in Treatment of Low Rectal Cancers: A Cross Sectional Study
Evaluation of Long-term Oncological Outcomes of Inter-Sphincter Resection Compared with Traditional Abdominoperineal Resection in Treatment of Low Rectal Cancers: A Cross Sectional Study Open
Objectives abdominoperineal resection (APR), is considered the gold standard surgical treatment for low rectal cancer. Patients with low rectal tumors, tumor’s distance less than 5 cm from the anal verge, are likely to require permanent co…
View article: Inferior Part of Rectus Abdominis Muscle Flap Outcomes after Abdominoperineal Resection: A Case Series Pilot Study.
Inferior Part of Rectus Abdominis Muscle Flap Outcomes after Abdominoperineal Resection: A Case Series Pilot Study. Open
Inferior part of rectus abdominis muscle flap was a reliable and comparable means of reconstruction after APR surgery with low rate of complications and mortality.
View article: An Expert Opinion Regarding the Management of Lower Gastrointestinal Cancers During COVID-19 Outbreak in Iran: A Brief Report
An Expert Opinion Regarding the Management of Lower Gastrointestinal Cancers During COVID-19 Outbreak in Iran: A Brief Report Open
Lower gastrointestinal cancer patients, like other immunosuppressed patients, are vulnerable to develop more severe infections. Iran is one of the countries with a high incidence of COVID-19, and some modifications are needed to adjust int…
View article: Inferior Part of Rectus Abdominis Muscle Flap Outcomes after Abdominoperineal Resection: A Case Series Pilot Study
Inferior Part of Rectus Abdominis Muscle Flap Outcomes after Abdominoperineal Resection: A Case Series Pilot Study Open
Inferior Part of Rectus Abdominis Muscle Flap Outcomes after Abdominoperineal Resection: A Case Series Pilot Study
View article: Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation
Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation Open
View article: Mechanical colon cleansing device in patients with chronic constipation: An experimental study
Mechanical colon cleansing device in patients with chronic constipation: An experimental study Open
Background: Constipation is one of the most common gastrointestinal discomforts that affects various age groups in humans. Different mechanical cleansing devices have been introduced yet. However, they are very expensive and not ava…
View article: Candidate Molecular Biomarkers for the Non- Invasive Detection of Colorectal Cancer using Gene Expression Profiling
Candidate Molecular Biomarkers for the Non- Invasive Detection of Colorectal Cancer using Gene Expression Profiling Open
The findings showed that the two candidate genes can be suggested as specific biomarkers for diagnosis of CRC using the peripheral blood as a non-invasive method. For a definite conclusion, more research is needed.
View article: Additional file 4 of Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation
Additional file 4 of Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation Open
Additional file 4: Table S3. All of the predicted lncRNAs for 9 hub miRNAs.
View article: Additional file 1 of Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation
Additional file 1 of Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation Open
Additional file 1: Table S1. Information obtained in the process of identification and selection of key genes including up-regulated genes with combined gene score > 3 of previous analysis (PMID: 31654507), up-regulated genes in carcinogen…
View article: Additional file 3 of Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation
Additional file 3 of Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation Open
Additional file 3: Table S2. Information of miRNA-mRNA network for 11 key genes.
View article: Intraperitoneal Lavage with Bupivacaine 0.2% and Post-operative Pain in Laparoscopic Colorectal Surgery: A Prospective, Double-Blind, Randomized Controlled Trial
Intraperitoneal Lavage with Bupivacaine 0.2% and Post-operative Pain in Laparoscopic Colorectal Surgery: A Prospective, Double-Blind, Randomized Controlled Trial Open
Background: Local anesthetics have been proven as a method to reduce postoperative pain and opioid use. It reduces side effects associated with drug use and may improve patient health and reduce hospital length of stay. The aim of this stu…
View article: Low expression of Talin1 is associated with advanced pathological features in colorectal cancer patients
Low expression of Talin1 is associated with advanced pathological features in colorectal cancer patients Open
View article: Therapeutic challenges in colorectal surgery practice during COVID-19 outbreak: a case series
Therapeutic challenges in colorectal surgery practice during COVID-19 outbreak: a case series Open
After the outbreak of COVID-19, several issues in the field of general surgery have remained unknown. Here we present two consecutive patients operated on in a coronavirus center in February 2020, during the outbreak in Tehran, Iran. Moreo…
View article: A novelty in laparoscopic total colectomy with natural orifice specimen extraction using a plastic cover
A novelty in laparoscopic total colectomy with natural orifice specimen extraction using a plastic cover Open
Introduction Minimally invasive colectomy has been performed for some years for many patients worldwide without much complications compared to the open approach. In this study we explained our experience regarding a modification in laparos…
View article: Inferior part of rectus abdominis muscle flap: A case report
Inferior part of rectus abdominis muscle flap: A case report Open
View article: Evaluating the effect of gentamicin-clindamycin lavage on post-operational pain and infection through laparoscopic colectomy surgery
Evaluating the effect of gentamicin-clindamycin lavage on post-operational pain and infection through laparoscopic colectomy surgery Open
Introduction Peritoneal antibiotic or normal saline lavage is seen to be beneficial in order to reduce the pain or infection risk through laparoscopic surgeries. It can also be applied for laparoscopic colectomy surgeries. In this study, w…