Mahdi Mojarrab
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View article: Cytoprotective Effect of Ethyl Acetate Extract of <i>Artemisia turanica</i>
Cytoprotective Effect of Ethyl Acetate Extract of <i>Artemisia turanica</i> Open
Background: Oxidative stress causes biological effects such as signaling changes, gene expression, mutagenesis, and apoptosis. Therefore, it is worthwhile to find new sources of natural antioxidants. Objectives: The purpose of this researc…
View article: Unveiling the Bioactive Potential of <i>Allium colchicifolium</i> Boiss Bulb Flavonoids: Anti-cancer Activities, and Computational Exploration of Anti-angiogenic Mechanisms
Unveiling the Bioactive Potential of <i>Allium colchicifolium</i> Boiss Bulb Flavonoids: Anti-cancer Activities, and Computational Exploration of Anti-angiogenic Mechanisms Open
Background: Plants of the genus Allium show significant anti-cancer properties due to various phytochemicals, including flavonoids. Objectives: This study investigated the cytotoxic activities of the methanolic extract of Allium colchicifo…
View article: Plant-Origin Coumarin-Hemiterpene Ethers and Their Chemotaxonomic Significance
Plant-Origin Coumarin-Hemiterpene Ethers and Their Chemotaxonomic Significance Open
Context: A particular class of coumarins, known as coumarin-hemiterpene ethers (CHEs), consists of a coumarin nucleus and a prenyloxy portion. No detailed report on natural coumarin-hemiterpene ethers (NCHEs) and their plant sources is ava…
View article: Biological Activity, Botanical Characteristics, and Phytochemical Constituents of <i>Artemisia ciniformis</i>
Biological Activity, Botanical Characteristics, and Phytochemical Constituents of <i>Artemisia ciniformis</i> Open
Context: Humans have used plants for their medicinal needs since ancient times. Artemisia is an important medicinal plant genus that includes about 500 different species, many of which are known for their therapeutic effects. One of the va…
View article: Acetylenic Metabolites and a 2-Phenoxychromone Derivative from the Aerial Parts of <i>Artemisia biennis</i>
Acetylenic Metabolites and a 2-Phenoxychromone Derivative from the Aerial Parts of <i>Artemisia biennis</i> Open
Background: Artemisia biennis is a weed of several crops, but some valuable biological effects have been reported from its various extracts. Objectives: The present phytochemical study was carried out on the dichloromethane (DCM) extract o…
View article: Anti-Fungal Effects of Aerial Part Extracts of Artemisia biennis, Artemisia ciniformis, and Artemisia turanica
Anti-Fungal Effects of Aerial Part Extracts of Artemisia biennis, Artemisia ciniformis, and Artemisia turanica Open
View article: Cytotoxic Activity and Phytochemical Analysis of Artemisia biennis Essential Oils at Different Growth Stages
Cytotoxic Activity and Phytochemical Analysis of Artemisia biennis Essential Oils at Different Growth Stages Open
Background: The Artemisia genus is well-known for its medicinal properties, particularly in Iranian traditional medicine. Artemisia biennis, a species within this genus, is widely distributed across Iranian rangelands. Objectives: This stu…
View article: Chemical Constituents of the Artemisia ciniformis Aerial Parts Grown in the Northeast of Iran and Their Chemotaxonomic Significance
Chemical Constituents of the Artemisia ciniformis Aerial Parts Grown in the Northeast of Iran and Their Chemotaxonomic Significance Open
Background: The Artemisia genus is one of the largest genera of the Asteraceae family, with various traditional and modern reported uses. Within this group, Artemisia ciniformis (Dermane Talaei) is an endemic plant of Iran with antioxidant…
View article: The Comparative Study on in vitro Antibacterial Effects of Different Aqueous Extracts of Artemisia Species (Short report)
The Comparative Study on in vitro Antibacterial Effects of Different Aqueous Extracts of Artemisia Species (Short report) Open
The Comparative Study on in vitro Antibacterial Effects of Different Aqueous Extracts of Artemisia Species (Short report)
View article: Antibacterial, Antibiofilm, Antiswarming, and Antioxidant Activities of Flavonoids Isolated from Allium colchicifolium Leaves
Antibacterial, Antibiofilm, Antiswarming, and Antioxidant Activities of Flavonoids Isolated from Allium colchicifolium Leaves Open
Allium (A.) species are one of the most widespread plants in the world, which have played a special role in terms of nutrition, treatment, and economy since long ago. This study is the first report on the phytochemical and biological activ…
View article: Inhibiting Angiogenesis by Anti-Cancer Saponins: From Phytochemistry to Cellular Signaling Pathways
Inhibiting Angiogenesis by Anti-Cancer Saponins: From Phytochemistry to Cellular Signaling Pathways Open
Saponins are one of the broadest classes of high-molecular-weight natural compounds, consisting mainly of a non-polar moiety with 27 to 30 carbons and a polar moiety containing sugars attached to the sapogenin structure. Saponins are found…
View article: Spiroketal-Enol Ethers and a Rare Flavonoid from the Aerial Parts of Artemisia Biennis
Spiroketal-Enol Ethers and a Rare Flavonoid from the Aerial Parts of Artemisia Biennis Open
View article: Evaluation of the Cytotoxicity of Aqueous Extract and Oleo-Essential Oil of Dorema ammoniacum Plant Oleo-Gum Resin in Some Human Cancer Cell Lines
Evaluation of the Cytotoxicity of Aqueous Extract and Oleo-Essential Oil of Dorema ammoniacum Plant Oleo-Gum Resin in Some Human Cancer Cell Lines Open
Background and Aim. This study is aimed at examining the cytotoxic and apoptotic activity of the aqueous extract and essential oil of Dorema ammoniacum D. Don gum toward some cancer cell lines. Experimental Procedure. The aqueous extract o…
View article: Salvigenin, a Trimethoxylated Flavone from Achillea Wilhelmsii C. Koch, Exerts Combined Lipid-Lowering and Mitochondrial Stimulatory Effects
Salvigenin, a Trimethoxylated Flavone from Achillea Wilhelmsii C. Koch, Exerts Combined Lipid-Lowering and Mitochondrial Stimulatory Effects Open
Phytochemical analysis of the Iranian plant Achillea wilhelmsii led to the isolation of 17 pure secondary metabolites belonging to the classes of sesquiterpenoids and phenolics. Two of these compounds, named wilhemsin (7) and wilhelmsolide…
View article: Antioxidant Activity-guided Phytochemical Investigation of <i>Artemisia aucheri</i> Boiss.: Isolation of Ethyl Caffeate and a Spinacetin Glycoside.
Antioxidant Activity-guided Phytochemical Investigation of <i>Artemisia aucheri</i> Boiss.: Isolation of Ethyl Caffeate and a Spinacetin Glycoside. Open
Antioxidant activity of five different extracts (petroleum ether, dichloromethane, ethyl acetate, ethanol and ethanol-water) of Artemisia aucheri aerial parts was investigated by three various methods: ferrous ion chelating (FIC) as…
View article: Investigation of Antioxidant Effects of Artemisia Sieberi Essential Oil In Iran
Investigation of Antioxidant Effects of Artemisia Sieberi Essential Oil In Iran Open
Background: Nowadays, Due to the destructive effects of chemicals on processed foods and increasing multidrug-resistant pathogens (MDRs), the use of essential oils of medicinal plants, is essential. Artemisia is the largest genus of the As…
View article: Isofraxidin: Synthesis, Biosynthesis, Isolation, Pharmacokinetic and Pharmacological Properties
Isofraxidin: Synthesis, Biosynthesis, Isolation, Pharmacokinetic and Pharmacological Properties Open
Isofraxidin (7-hydroxy-6, 8-dimethoxy coumarin) (IF) is a hydroxy coumarin with several biological and pharmacological activities. The plant kingdom is of the most prominent sources of IF, which, among them, Eleutherococcus and Fraxinus ar…
View article: Isolation of Two Isochlorogenic Acid Isomers from Phenolic Rich Fraction of <i>Artemisia</i> <i>turanica</i> Krasch.
Isolation of Two Isochlorogenic Acid Isomers from Phenolic Rich Fraction of <i>Artemisia</i> <i>turanica</i> Krasch. Open
Total phenolic content (TPC) and antioxidant capacity of five different extracts (petroleum ether (40-60), dichloromethane, ethyl acetate, ethanol and ethanol-water (1:1 v/v)) of Artemisia turanica (A. turanica) aerial parts were de…
View article: Comparison of the cytotoxic effects of different fractions of Artemisia ciniformis and Artemisia biennis on B16/F10, PC3 and MCF7 Cells
Comparison of the cytotoxic effects of different fractions of Artemisia ciniformis and Artemisia biennis on B16/F10, PC3 and MCF7 Cells Open
A. biennis and A. ciniformis are suggested as the potential sources of cytotoxic phytochemicals. The probable presence of terpenoids, steroids, and alkaloids in the selected fractions is proposed based on the preliminary phyt…
View article: Flavonoids from the Aerial Parts of Artemisia biennis Willd
Flavonoids from the Aerial Parts of Artemisia biennis Willd Open
Background: The current phytochemical study was carried out on a fraction of dried polar extract of aerial parts of Artemisia biennis Willd. which was previously reported to decrease the viability of the rat pheochromocytoma cell line PC12…
View article: Dicaffeoylquinic Acids from the Aerial Parts of Artemisia ciniformis Krasch. & Popov ex Poljakov
Dicaffeoylquinic Acids from the Aerial Parts of Artemisia ciniformis Krasch. & Popov ex Poljakov Open
Background: Artemisia ciniformis (A. ciniformis) belongs to the genus Artemisia and grows at northeast of Iran. The current phytochemical study was carried out on the most potent extract in cell-free antioxidant assays. Methods: Hydroethan…
View article: The protective effect of different extracts of aerial parts of Artemisia ciniformis against H2O2-induced oxidative stress and apoptosis in PC12 pheochromocytoma cells
The protective effect of different extracts of aerial parts of Artemisia ciniformis against H2O2-induced oxidative stress and apoptosis in PC12 pheochromocytoma cells Open
Phytochemicals from mulberry extract (Morus sp.): Antioxidant and neuroprotective potentialsOlfa REBAI, Manel BELKHIR, Sami FATTOUCH, Mohamed AMRI
View article: Cytotoxic and Apoptogenic Sesquiterpenoids from the Petroleum Ether Extract of <i>Artemisia aucheri</i> Aerial Parts.
Cytotoxic and Apoptogenic Sesquiterpenoids from the Petroleum Ether Extract of <i>Artemisia aucheri</i> Aerial Parts. Open
Different types of Artemisia aucheri extracts were reported to have various biological activities including a cytotoxic effect on some cancer cell lines. We investigated the antiproliferative activity of isolated sesquiterpenoids fr…
View article: Active fractions of dichloromethane extract of Artemisia Aucheri inhibit proliferation of human breast cancer MCF-7 cells via induction of apoptosis
Active fractions of dichloromethane extract of Artemisia Aucheri inhibit proliferation of human breast cancer MCF-7 cells via induction of apoptosis Open
The antiproliferative effect of dichloromethane extract of Artemisia aucheri (A. aucheri) has been demonstrated previously on human cancerous cell lines. In the current study, further fractionation was carried out on the dichloromethane ex…
View article: The Protective Effect of Different Extracts of Three <i>Artemisia</i> Species against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress and Apoptosis in PC12 Neuronal Cells.
The Protective Effect of Different Extracts of Three <i>Artemisia</i> Species against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress and Apoptosis in PC12 Neuronal Cells. Open
Artemisia turanica and Artemisia turcomanica extracts were found to potentially exert neuroprotective effect on PC12 cells. The results exhibited that the cytoprotective potential and anti-apoptotic mechanism of these species…
View article: Evaluation of antioxidant activity and identification of main compounds of various extracts of Artemisia turanica aerial parts
Evaluation of antioxidant activity and identification of main compounds of various extracts of Artemisia turanica aerial parts Open
Background and objectives: Artemisia turanica Krash. grows wildly in north-eastern Iran. The aim of the present work was to undertake an investigation of the antioxidant activity as well as identification of main compound of different extr…
View article: Flavonoids from the aerial parts of Artemisia biennis Willd
Flavonoids from the aerial parts of Artemisia biennis Willd Open
Background and objectives: The genus Artemisia contains over 250 species all over the world. A. biennis Willd is one of the species which grows wildly in Iran. Camphor and (E)-beta-farnesene have been reported as the major components of th…
View article: Evaluation of antioxidant activity and phenolic contents and identification of main compounds of various extracts from Artemisia aucheri aerial parts
Evaluation of antioxidant activity and phenolic contents and identification of main compounds of various extracts from Artemisia aucheri aerial parts Open
Background and objectives: Artemisia aucheri Boiss. is regarded as one of 34 Artemisia species growing in Iran. The aim of this study was to undertake an investigation of the antioxidant activity as well as identification of main compound …
View article: Cytotoxic and apoptotic effects of different extracts of <i>Artemisia biennis</i> Willd. on K562 and HL-60 cell lines.
Cytotoxic and apoptotic effects of different extracts of <i>Artemisia biennis</i> Willd. on K562 and HL-60 cell lines. Open
The results can corroborate the cytotoxic and apoptotic effects of the CH2Cl2 extract of A. biennis on the K562 and HL-60 cancer cell lines.
View article: Cytotoxic Properties of Three Isolated Coumarin-hemiterpene Ether Derivatives from <i>Artemisia armeniaca</i> Lam.
Cytotoxic Properties of Three Isolated Coumarin-hemiterpene Ether Derivatives from <i>Artemisia armeniaca</i> Lam. Open
Considering multiple reports on cytotoxic activity of the Artemisia genus and its phytochemicals, in the current study A. armeniaca Lam. and the three components isolated from the plant were subjected to cytotoxic studies. An…