Mahmood Dehghani Ashkezari
YOU?
Author Swipe
View article: Exploring the anticancer and apoptotic potential of Verbena officinalis L. extracts in combination with conventional chemotherapy for pancreatic cancer: A multifaceted in vitro study on PANC-1 cells
Exploring the anticancer and apoptotic potential of Verbena officinalis L. extracts in combination with conventional chemotherapy for pancreatic cancer: A multifaceted in vitro study on PANC-1 cells Open
This study evaluated the anticancer and apoptotic potential of different Verbena officinalis (VO) extracts on human pancreatic adenocarcinoma PANC-1 cells compared to normal HUVEC cells. We assessed the antioxidant capacity through total p…
View article: The Evaluation of the N-cadherin Promoter’s ability to Block EMT by Specific Expression of Diphtheria Toxin in EMT-induced A549 Cell Lines
The Evaluation of the N-cadherin Promoter’s ability to Block EMT by Specific Expression of Diphtheria Toxin in EMT-induced A549 Cell Lines Open
During epithelial to mesenchymal transition, the ability of cancer cells to transform and metastasize is primarily determined by N-cadherin-mediated migration and invasion. This study aimed to evaluate whether the N-cadherin promoter can i…
View article: Investigation the Expression Levels of MIR-181 and Hoxa11 Gene in Eutopic and Ectopic Endometrial Tissue
Investigation the Expression Levels of MIR-181 and Hoxa11 Gene in Eutopic and Ectopic Endometrial Tissue Open
MiR-181 and HOXA11 are promising strategies in endometriosis disease. Understanding this relation and regulation roles contribute to realizing the etiology of endometriosis.
View article: The Effect of The Conditioned Medium from Human Embryonic Stem Cells on Mouse Oocytes In Vitro Maturation.
The Effect of The Conditioned Medium from Human Embryonic Stem Cells on Mouse Oocytes In Vitro Maturation. Open
Similar to some other studies, the secretome of the HESCM showed a significant impact on the IVM outcomes in mice.
View article: Retraction Note: The Effect of Zinc Supplementation on Expressed Levels of Peroxisome Proliferator-Activated Receptor Gamma and Glucose Transporter Type 1 Genes in Newborns of Women with Gestational Diabetes Mellitus
Retraction Note: The Effect of Zinc Supplementation on Expressed Levels of Peroxisome Proliferator-Activated Receptor Gamma and Glucose Transporter Type 1 Genes in Newborns of Women with Gestational Diabetes Mellitus Open
View article: Investigating the Molecular miRNAs as Biomarkers of Type 2 Diabetes
Investigating the Molecular miRNAs as Biomarkers of Type 2 Diabetes Open
Introduction: Biomarkers would significantly improve the early detection of the disease and identification of individuals at risk of emerging complications. Diabetes mellitus is a group of diverse and complex metabolic disorders. Both type…
View article: Investigating the Relation between LCK Gene Expression with Type 2 Diabetes Patients in Yazd Diabetes Research Center
Investigating the Relation between LCK Gene Expression with Type 2 Diabetes Patients in Yazd Diabetes Research Center Open
Objective: Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance and insulin secretory defect. Deficiency of cellular immunity is known as one of the factors involved in the pathogenesis of T2DM. lymphocyte-specific protei…
View article: Preparation and preclinical characterization of 111 In-DTPA-Anti-MUC1 as a radioimmunoconjugate for diagnosis of breast cancer by single-photon emission computed tomography
Preparation and preclinical characterization of 111 In-DTPA-Anti-MUC1 as a radioimmunoconjugate for diagnosis of breast cancer by single-photon emission computed tomography Open
Context: Targeting MUC1 antigens which are overexpressed in 80% of breast cancers can be widely used in the field of radioimmunoscintigraphy (RIS) of breast cancer. Aims: The aim of this study was to develop a new diagnostic labeled compou…
View article: The effect of the human cumulus cells-conditioned medium on in vitro maturation of mouse oocyte: An experimental study
The effect of the human cumulus cells-conditioned medium on in vitro maturation of mouse oocyte: An experimental study Open
Background: To increase the results of infertility treatment, many efforts have been made to improve the treatment methods. As assisted reproductive technology is mainly using cell culture methods, one of the approaches to improve this tec…
View article: The Effects of In Vitro Incubation of Asthenoteratozoospermic Semen after Density Gradient Centrifugation at Room Temperature and 37C on Sperm Parameters, Chromatin Quality and DNA Fragmentation in a Short Time Period
The Effects of In Vitro Incubation of Asthenoteratozoospermic Semen after Density Gradient Centrifugation at Room Temperature and 37C on Sperm Parameters, Chromatin Quality and DNA Fragmentation in a Short Time Period Open
Background: Sperm quality is an important factor in assisted reproductive technology (ART) that affects the success rate of infertile couples treatment. In vitro incubation of sperm can influence its parameters and DNA integrity. The prese…
View article: <p>Circulating miR-15a and miR-222 as Potential Biomarkers of Type 2 Diabetes</p>
Circulating miR-15a and miR-222 as Potential Biomarkers of Type 2 Diabetes Open
This study indicated that the plasma expression levels of miR-222 and miR-15a can be considered as non-invasive, fast tools to separate the pre-T2D individuals from their healthy counterparts. Accordingly, this information could be used to…
View article: Effect of Human Testicular Cells Conditioned Medium on <i>In Vitro</i> Maturation and Morphology of Mouse Oocytes.
Effect of Human Testicular Cells Conditioned Medium on <i>In Vitro</i> Maturation and Morphology of Mouse Oocytes. Open
Our findings show that TCCM supports oocyte IVM in mice and affect oocyte morphology.
View article: FISH-based sperm aneuploidy screening in male partner of women with a history of recurrent pregnancy loss
FISH-based sperm aneuploidy screening in male partner of women with a history of recurrent pregnancy loss Open
Background Recurrent pregnancy loss is defined as having the experience of three or more repeated pregnancy losses. Despite numerous studies, RPL etiology remains unclear; in this respect, many etiological factors have been thoroughly inve…
View article: Antitumoral potential of microvesicles extracted from human adipose-derived mesenchymal stem cells on human breast cancer cells
Antitumoral potential of microvesicles extracted from human adipose-derived mesenchymal stem cells on human breast cancer cells Open
Taking together, AT-MSC-derived MVs demonstrated anticancer or antitumoral properties on MCF-7 cells, and it could also be effective for other types of cancer cells.
View article: Analysis of BMP4 (rs121912765) polymorphism in Iranian women with history of recurrent spontaneous abortion: A case-control study
Analysis of BMP4 (rs121912765) polymorphism in Iranian women with history of recurrent spontaneous abortion: A case-control study Open
Recurrent spontaneous abortion (RSA) defines as the consecutive loss of at least two pregnancies prior to the 20th week of gestation. A qualitative diagnosis of infertility can only be performed by focusing on female and male physical abno…
View article: WNT7A (rs104893832) polymorphism increases the risk of recurrent spontaneous abortion in Iranian women
WNT7A (rs104893832) polymorphism increases the risk of recurrent spontaneous abortion in Iranian women Open
BACKGROUNDRecurrent spontaneous abortion is defined as the occurrence of three or more clinical miscarriages in one woman. Several factors, including genetics and environmental factors, are involved in this kind of infertility, in which WN…
View article: SuO041BONE MARROW MESENCHYMAL STROMAL CELLS REDUCED CYSTOGENIC POTENTIAL OF CD133+ PROGENITOR CELLS OF HUMAN POLYCYSTIC KIDNEYS
SuO041BONE MARROW MESENCHYMAL STROMAL CELLS REDUCED CYSTOGENIC POTENTIAL OF CD133+ PROGENITOR CELLS OF HUMAN POLYCYSTIC KIDNEYS Open