Mahmoud Diab
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View article: Sex differences on the effect of hemoadsorption during cardiac surgery – A REMOVE trial post-hoc analysis
Sex differences on the effect of hemoadsorption during cardiac surgery – A REMOVE trial post-hoc analysis Open
The intraoperative use of hemoadsorption was not associated with reduction of postoperative organ dysfunction, 30-day mortality, or other major clinical endpoints in both sex subgroups.
View article: Complete Esophageal Obstruction Due to Dysphagia Lusoria and Subclavian Artery Thrombosis: A Case Report
Complete Esophageal Obstruction Due to Dysphagia Lusoria and Subclavian Artery Thrombosis: A Case Report Open
View article: Depression in Patients With Symptomatic Aortic Stenosis Predicts 3-Year Mortality After Transcatheter Aortic Valve Implantation
Depression in Patients With Symptomatic Aortic Stenosis Predicts 3-Year Mortality After Transcatheter Aortic Valve Implantation Open
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View article: Aortic and Mitral Valve Endocarditis—Simply Left-Sided Endocarditis or Different Entities Requiring Individual Consideration?—Insights from the CAMPAIGN Database
Aortic and Mitral Valve Endocarditis—Simply Left-Sided Endocarditis or Different Entities Requiring Individual Consideration?—Insights from the CAMPAIGN Database Open
Background: Aortic valve infective endocarditis (AV-IE) and mitral valve infective endocarditis (MV-IE) are often grouped together as one entity: left-sided endocarditis. However, there are significant differences between the valves in ter…
View article: SpannerLib: Embedding Declarative Information Extraction in an Imperative Workflow
SpannerLib: Embedding Declarative Information Extraction in an Imperative Workflow Open
Document spanners have been proposed as a formal framework for declarative Information Extraction (IE) from text, following IE products from the industry and academia. Over the past decade, the framework has been studied thoroughly in term…
View article: Incidence and Outcomes of Emergency Intraprocedural Surgical Conversion During Transcatheter Aortic Valve Implantation: A Multicentric Analysis
Incidence and Outcomes of Emergency Intraprocedural Surgical Conversion During Transcatheter Aortic Valve Implantation: A Multicentric Analysis Open
View article: Outcomes of complete removal versus conservative therapy in cardiac implantable electronic device infections – A systematic review and Meta-analysis
Outcomes of complete removal versus conservative therapy in cardiac implantable electronic device infections – A systematic review and Meta-analysis Open
The analysis indicates that patients with a CIED infection who undergo complete CIED extraction exhibit a lower rate of relapse/re-infection. Additionally, a lower short- and mid-term mortality is observed, although it is acknowledged that…
View article: Conservative Versus Surgical Therapy in Patients With Infective Endocarditis and Surgical Indication—Meta‐Analysis of Reconstructed Time‐to‐Event Data
Conservative Versus Surgical Therapy in Patients With Infective Endocarditis and Surgical Indication—Meta‐Analysis of Reconstructed Time‐to‐Event Data Open
Background Infective endocarditis represents a life‐threatening disease with high mortality rates. A fraction of patients receives exclusively conservative antibiotic treatment due to their comorbidities and high operative risk, despite fu…
View article: Durability of Tricuspid Valve Repair in Patients Undergoing Left Ventricular Assist Device Implantation
Durability of Tricuspid Valve Repair in Patients Undergoing Left Ventricular Assist Device Implantation Open
Objectives: Benefits of tricuspid valve repair (TVR) in left ventricular assist device (LVAD) patients have been questioned. High TVR failure rates have been reported. Remaining or recurring TR was found to be a risk factor for right heart…
View article: A novel therapeutic combination of vildagliptin and agomelatine alleviates the nephropathy in streptozocininduced diabetic rats: A structural & biochemical study
A novel therapeutic combination of vildagliptin and agomelatine alleviates the nephropathy in streptozocininduced diabetic rats: A structural & biochemical study Open
Diabetes mellitus is a worldwide epidemic causes numerous health problems including nephropathy and depression which are caused by oxygen radicals.We investigated the antioxidative effects of agomelatine or vildagliptin on streptozotocin-i…
View article: Antithrombotic Therapy in Patients With Infective Endocarditis
Antithrombotic Therapy in Patients With Infective Endocarditis Open
ATT in IE patients was not associated with higher frequency of cerebrovascular events or ICH. Moreover, we found that the use of anticoagulation was associated with decreased in-hospital mortality and the use of antiplatelets was associate…
View article: Comparing outcomes between coronary artery bypass grafting and percutaneous coronary intervention in octogenarians with left main or multivessel disease
Comparing outcomes between coronary artery bypass grafting and percutaneous coronary intervention in octogenarians with left main or multivessel disease Open
Mechanisms of coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) differ as CABG provides surgical collateralization and may prolong life by preventing future myocardial infarctions (MI). However, CABG benef…
View article: Real-world outcome and long-term survival analysis after trans-catheter aortic valve implantation (TAVI) - does age matter?
Real-world outcome and long-term survival analysis after trans-catheter aortic valve implantation (TAVI) - does age matter? Open
Background Transcatheter aortic valve implantation (TAVI) is the treatment of choice in elderly patients irrespective of surgical risk. Since a clear cut-off in age is still a matter of debate during heart team decision making between TAVI…
View article: Short- and long-term results of total arch replacement for acute type I aortic dissection in comparison to hemiarch replacement: a 10-year follow-up analysis
Short- and long-term results of total arch replacement for acute type I aortic dissection in comparison to hemiarch replacement: a 10-year follow-up analysis Open
Background Optimal management of the arch in cases of acute type-A aortic dissection (ATAAD) involving the aortic arch (DeBakey type I) is still controversial. Extended total arch replacement (TAR) to address re-entries increases the compl…
View article: Blood cardioplegia may be better than crystalloid cardioplegia during cardiac surgery for infective endocarditis
Blood cardioplegia may be better than crystalloid cardioplegia during cardiac surgery for infective endocarditis Open
Background Cardioplegia is an indispensable element in cardiac surgery for left sided infective endocarditis (IE). Crystalloid cardiolegia (CC) as a single or dual-dose is more attractive in complicated IE surgery than repeated, every 15-2…
View article: Does the use of anticoagulation or antiplatelet therapy increase cerebrovascular events in patients with infective endocarditis - a systematic review and meta-analysis
Does the use of anticoagulation or antiplatelet therapy increase cerebrovascular events in patients with infective endocarditis - a systematic review and meta-analysis Open
Background Management of anticoagulant and antiplatelet therapy in patients with infective endocarditis (IE) remains challenging. We aimed to evaluate the impact of antiplatelet and anticoagulant therapy on cerebrovascular events (CVE) and…
View article: Outcomes of Concomitant Coronary Artery Bypass Grafting in Patients With Infective Endocarditis: A Systematic Review and Meta-Analysis
Outcomes of Concomitant Coronary Artery Bypass Grafting in Patients With Infective Endocarditis: A Systematic Review and Meta-Analysis Open
It is current practice to perform concomitant coronary artery bypass grafting (CABG) in patients with infective endocarditis who have relevant coronary artery disease. However, CABG may add complexity to the operation. We performed a syste…
View article: Hemoadsorption in Heart Failure Requiring Mechanical Circulatory Support—A Systematic Review and Meta-Analysis
Hemoadsorption in Heart Failure Requiring Mechanical Circulatory Support—A Systematic Review and Meta-Analysis Open
Background: Left ventricular assist devices (LVAD) and extracorporeal membrane oxygenation (ECMO) are well established therapies in heart failure (HF) management. Their use is generally associated with a sudden increase in inflammatory med…
View article: Rezidivierende Serratia-marcescens-Bakteriämie: Wer suchet, der findet
Rezidivierende Serratia-marcescens-Bakteriämie: Wer suchet, der findet Open
View article: Prognostic relevance of mitral and tricuspid regurgitation after transcatheter aortic valve implantation: Impact of follow-up time point for decision-making
Prognostic relevance of mitral and tricuspid regurgitation after transcatheter aortic valve implantation: Impact of follow-up time point for decision-making Open
Background In patients with aortic stenosis treated by transcatheter aortic valve implantation (TAVI), mitral and tricuspid regurgitation (MR and TR) at baseline and after TAVI are likely to be of prognostic relevance, and questions such a…
View article: Intraoperative Cell Savage, Infection and Organ Failure in Infective Endocarditis Patients—A Retrospective Single Center Evaluation
Intraoperative Cell Savage, Infection and Organ Failure in Infective Endocarditis Patients—A Retrospective Single Center Evaluation Open
Surgery is indicated in about 50% of infective endocarditis patients, and bleeding or the transfusion of blood a common finding. The intraoperative use of cell salvage may reduce the perioperative transfusion requirement, but its use is li…
View article: Effect of COVID 19 Infection on ST Elevation Myocardial Infarction (STEMI)Patients Managed by Primary PCI
Effect of COVID 19 Infection on ST Elevation Myocardial Infarction (STEMI)Patients Managed by Primary PCI Open
A life-threatening cardiovascular-emergency called ST elevation myocardial infarction (STEMI) necessitates immediate intervention for reperfusion.COVID-19 has a negative effect on STEMI patients.The purpose of this work was to contrast ind…
View article: Adding troponin to echocardiography improves preoperative abscess detection in infective endocarditis. A REMOVE Trial analysis
Adding troponin to echocardiography improves preoperative abscess detection in infective endocarditis. A REMOVE Trial analysis Open
Background Detection of cardiac abscess in patients with infective endocarditis (IE) is important for surgical planning and decision-making. While transesophageal echocardiography (TEE) is the method of choice for abscess detection, in man…
View article: Tricuspid regurgitation and atrial fibrillation at baseline independently predict two-year survival after transcatheter aortic valve implantation (TAVI)
Tricuspid regurgitation and atrial fibrillation at baseline independently predict two-year survival after transcatheter aortic valve implantation (TAVI) Open
Background Transcatheter aortic valve implantation (TAVI) is the accepted state-of-the-art treatment for elderly patients suffering from severe symptomatic aortic stenosis (AS). Co-morbidities at baseline are of great impact not only for i…
View article: Prognostic relevance of mitral regurgitation at different follow-up timepoints after transcatheter aortic valve implantation (TAVI): implications for therapeutic decision making?
Prognostic relevance of mitral regurgitation at different follow-up timepoints after transcatheter aortic valve implantation (TAVI): implications for therapeutic decision making? Open
Background Transcatheter aortic valve implantation (TAVI) has developed rapidly in the last decade and is now recommended as state-of-the-art treatment for elderly patients suffering from severe symptomatic degenerative aortic stenosis (AS…
View article: Response by Diab et al to Letter Regarding Article, “Cytokine Hemoadsorption During Cardiac Surgery Versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results From a Multicenter Randomized Controlled Trial”
Response by Diab et al to Letter Regarding Article, “Cytokine Hemoadsorption During Cardiac Surgery Versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results From a Multicenter Randomized Controlled Trial” Open
View article: Bend relief fenestration might prevent outflow graft obstruction in patients with left ventricular assist device
Bend relief fenestration might prevent outflow graft obstruction in patients with left ventricular assist device Open
OBJECTIVES Patients with left ventricular assist devices may experience external obstruction of the outflow graft through a gelatinous substance within the bend relief (BR; a stiff tube graft guiding the outflow graft). Preventative strate…
View article: Surgical Timing in Patients With Infective Endocarditis and With Intracranial Hemorrhage: A Systematic Review and Meta‐Analysis
Surgical Timing in Patients With Infective Endocarditis and With Intracranial Hemorrhage: A Systematic Review and Meta‐Analysis Open
Background Intracranial hemorrhage (ICH) is one of the main causes for lack of surgery in patients with infective endocarditis (IE), despite the presence of surgical indications. We aimed to evaluate the impact of early surgery in patients…
View article: Prediction of one- and two-year mortality after transcatheter aortic valve implantation: proposal of a fast sum-score system integrating a novel biomarker of cardiac extracellular matrix accumulation and fibrosis
Prediction of one- and two-year mortality after transcatheter aortic valve implantation: proposal of a fast sum-score system integrating a novel biomarker of cardiac extracellular matrix accumulation and fibrosis Open
Background: Prediction of long-term mortality in patients with severe symptomatic aortic valve stenosis undergoing transcatheter aortic valve implantation (TAVI) is still challenging but of great impact with respect to the selection of tre…
View article: Surgery for infective endocarditis following low-intermediate risk transcatheter aortic valve replacement—a multicentre experience
Surgery for infective endocarditis following low-intermediate risk transcatheter aortic valve replacement—a multicentre experience Open
OBJECTIVES With the expansion of transcatheter aortic valve replacement (TAVR) into intermediate and low risk, the number of TAVR procedures is bound to rise and along with it the number of cases of infective endocarditis following TAVR (T…