Mahmoud Mahmoudi
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View article: Nano-curcumin potentiates antitumor immunity in prostate cancer via co-culture with adipose-derived mesenchymal stem cells
Nano-curcumin potentiates antitumor immunity in prostate cancer via co-culture with adipose-derived mesenchymal stem cells Open
Nano-curcumin in combination with ASCs has the potential to affect immune cells, indicating its potential as a complementary therapy for use in cancer. Further research is required to confirm these findings.
View article: Unveiling the hidden aggression: a rare case of uterine leiomyosarcoma and its diagnostic dilemmas
Unveiling the hidden aggression: a rare case of uterine leiomyosarcoma and its diagnostic dilemmas Open
Introduction and importance: Uterine leiomyosarcoma (uLMS) is a rare and highly aggressive malignancy of the uterine myometrium, accounting for only 1–2% of uterine cancers. Due to its nonspecific presentation and the difficulty in disting…
View article: Probiotic Interventions in Systemic Sclerosis Patients: A Systematic Review and Future Prospects
Probiotic Interventions in Systemic Sclerosis Patients: A Systematic Review and Future Prospects Open
Background and Aims Systemic sclerosis (SSc) is an uncommon autoimmune connective tissue disease distinguished by fibrosis and vascular abnormalities, often leading to gastrointestinal problems. This review explores the potential of probio…
View article: Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights
Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights Open
A large body of evidence suggests that mesenchymal stromal cells (MSCs) are able to respond rapidly to the cytokine milieu following systemic infusion. This encounter has the potential to dictate their therapeutic efficacy (also referred t…
View article: Applying Radial Basis Functions and Partition of Unity for Solving Heating Equations Optimal Control Issues
Applying Radial Basis Functions and Partition of Unity for Solving Heating Equations Optimal Control Issues Open
View article: Curcumin and Berberine Arrest Maturation and Activation of Dendritic CellsDerived from Lupus Erythematosus Patients
Curcumin and Berberine Arrest Maturation and Activation of Dendritic CellsDerived from Lupus Erythematosus Patients Open
Background:: Systemic lupus erythematosus (SLE) is a complex autoimmune disease recognized by elevated activity of autoimmune cells, loss of tolerance, and decreased regulatory T cells producing inhibitory cytokines. Despite many efforts, …
View article: Evaluation of the immune-modulatory, anti-oxidant, proliferative, and anti-apoptotic effects of nano-silymarin on mesenchymal stem cells isolated from multiple sclerosis patients' adipose tissue sources
Evaluation of the immune-modulatory, anti-oxidant, proliferative, and anti-apoptotic effects of nano-silymarin on mesenchymal stem cells isolated from multiple sclerosis patients' adipose tissue sources Open
Silymarin (SL) has a long history of use for the treatment of a variety of diseases, but several limitations, such as poor bioavailability and negligible solubility, have restricted its successful translation in a clinical setting. However…
View article: A new generation of mesenchymal stromal/stem cells differentially trained by immunoregulatory probiotics in a lupus microenvironment
A new generation of mesenchymal stromal/stem cells differentially trained by immunoregulatory probiotics in a lupus microenvironment Open
View article: The effects of Lactobacillus delbrueckii and Lactobacillus rhamnosus on cytokines and their related molecules: An <em>ex vivo</em> study on patients with systemic lupus erythematosus
The effects of Lactobacillus delbrueckii and Lactobacillus rhamnosus on cytokines and their related molecules: An <em>ex vivo</em> study on patients with systemic lupus erythematosus Open
Objectives: This study aimed to assess the ex vivo impact of Lactobacillus delbrueckii (L. delbrueckii) and Lactobacillus rhamnosus (L. rhamnosus) on inflammatory and anti-inflammatory cytokines as well as their related molecules on the pe…
View article: Potential Therapy for Multiple Sclerosis (MS): Investigating the effects of 1,25-dihydroxycholecalciferol on T regulatory cells in Patients with MS
Potential Therapy for Multiple Sclerosis (MS): Investigating the effects of 1,25-dihydroxycholecalciferol on T regulatory cells in Patients with MS Open
The active form of 1,25-dihydroxycholecalciferol and mesenchymal stem cells (MSCs) have immunomodulatory effects on the immune system and could be helpful for regenerative therapeutic application in neurodegenerative diseases. The MSCs wer…
View article: Probiotics as a complementary treatment in systemic lupus erythematosus: A systematic review
Probiotics as a complementary treatment in systemic lupus erythematosus: A systematic review Open
Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that primarily affects young women. SLE has no recognized etiology but it is believed to be triggered by a number of factors, including genetic predisposition,…
View article: Cobalt ferrite nanoparticle for the elimination of CD133+CD44+ and CD44+CD24−, in breast and skin cancer stem cells, using non-ionizing treatments
Cobalt ferrite nanoparticle for the elimination of CD133+CD44+ and CD44+CD24−, in breast and skin cancer stem cells, using non-ionizing treatments Open
View article: The effect and Follow – up results of 8 weeks of operational-skill training on the dynamic balance of firefighters
The effect and Follow – up results of 8 weeks of operational-skill training on the dynamic balance of firefighters Open
Introduction: Rescue worker is one of the jobs that is associated with stressful factors. Among the relief occupations, firefighters are faced various physical and chemical hazards, such as high temperatures, chemicals, noise, etc., due to…
View article: The effects of culture-expanded, non-cryopreserved adipose tissue mesenchymal stem cells (AT-MSCs) on neurological and immunological paradigms in females with secondary progressive multiple sclerosis: a phase I/II clinical trial
The effects of culture-expanded, non-cryopreserved adipose tissue mesenchymal stem cells (AT-MSCs) on neurological and immunological paradigms in females with secondary progressive multiple sclerosis: a phase I/II clinical trial Open
Objective Mesenchymal stem cells (MSCs) due to their immunomodulatory, neurogenerative and self-renewal features have achieved fascinating prospects in regenerative medicine. Adipose tissue is an optimal source of MSCs because of the high …
View article: The role of melatonin as an adjuvant in the treatment of COVID-19: A systematic review
The role of melatonin as an adjuvant in the treatment of COVID-19: A systematic review Open
This systematic review highlights the probable role of melatonin as a potential adjuvant in the treatment of COVID-19 after about two weeks of consumption. However, further high-quality randomized clinical trials are required.
View article: Enhancing the efficacy of <i>Hypericum perforatum</i> in the treatment of an experimental model of multiple sclerosis using gold nanoparticles: an <i>in vivo</i> study.
Enhancing the efficacy of <i>Hypericum perforatum</i> in the treatment of an experimental model of multiple sclerosis using gold nanoparticles: an <i>in vivo</i> study. Open
The current study demonstrated that HPE-GNP could potentially reduce clinical and pathological complications of EAE, but laboratory data showed that HPE-GNP was significantly more effective than HPE in the treatment of EAE.
View article: The impact of lymphoid memory cells in different ages of COVID-19 patients
The impact of lymphoid memory cells in different ages of COVID-19 patients Open
View article: Inhibitory effects of tolerogenic probiotics on migratory potential of lupus patient-derived DCs.
Inhibitory effects of tolerogenic probiotics on migratory potential of lupus patient-derived DCs. Open
The results demonstrated that tolerogenic probiotics could prevent or decrease the expression of inflammatory CRs on the surface of tolerogenic DCs during the maturation process.
View article: Comparison of Serum Total IgA Levels in Severe and Mild COVID-19 Patients and Control Group
Comparison of Serum Total IgA Levels in Severe and Mild COVID-19 Patients and Control Group Open
View article: Differences in autoimmunity factors based on the activity of thromboangiitis obliterans
Differences in autoimmunity factors based on the activity of thromboangiitis obliterans Open
The findings of this study indicate that BD may closely be correlated to transient autoimmune phenomena, despite the fact that further research is required to investigate how transient unspecific autoimmune reactions contribute to the BD p…
View article: Comparative assessment of proliferation and immunomodulatory potential of Hypericum perforatum plant and callus extracts on mesenchymal stem cells derived adipose tissue from multiple sclerosis patients
Comparative assessment of proliferation and immunomodulatory potential of Hypericum perforatum plant and callus extracts on mesenchymal stem cells derived adipose tissue from multiple sclerosis patients Open
View article: Prognostic Value of Serum MICA Levels as a Marker of Severity in COVID-19 Patients
Prognostic Value of Serum MICA Levels as a Marker of Severity in COVID-19 Patients Open
Purpose: The global pandemic of COVID-19 and high mortality rates, necessitate the development of diagnostic and prognostic tools and expansion of testing capacity. The existing approaches to identification and characterization of SARS-COV…
View article: Prevalence and genetic characterization of Cryptosporidium in pre-weaned cattle in Urmia (Northwestern Iran)
Prevalence and genetic characterization of Cryptosporidium in pre-weaned cattle in Urmia (Northwestern Iran) Open
Introduction: Cryptosporidiosis is a zoonotic disease causing digestive problems in pre-weaned calves. Considering the zoonosis of the parasite and its importance in veterinary medicine, we evaluated the prevalence and genotyping of Crypto…
View article: Design of a Model for Management of Referral System in the Iranian Urban Family Physician Program
Design of a Model for Management of Referral System in the Iranian Urban Family Physician Program Open
Background: The purpose of this research was to identify the main dimensions of management of referral systems in family physician program and then introduce them to policymakers of the country primary health care. Methods: This descriptiv…
View article: The immunomodulatory effects of mesenchymal stromal cell‐based therapy in human and animal models of systemic lupus erythematosus
The immunomodulatory effects of mesenchymal stromal cell‐based therapy in human and animal models of systemic lupus erythematosus Open
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune inflammatory disease with no absolute cure. Although the exact etiopathogenesis of SLE is still enigmatic, it has been well demonstrated that a combination of genetic pred…
View article: Author response for "<i>Dicrocoelium</i> Ova Can Block the Induction Phase of Experimental Autoimmune Encephalomyelitis"
Author response for "<i>Dicrocoelium</i> Ova Can Block the Induction Phase of Experimental Autoimmune Encephalomyelitis" Open
View article: Designing a Quality Management Model for Health Services in Iran
Designing a Quality Management Model for Health Services in Iran Open
Introduction: Nowadays, the quality of services, especially in high volume clients, such as financial and care services, has become increasingly important. Therefore, quality of service in accordance with professional standards and custome…
View article: Single Nucleotide Polymorphisms of FCRL3 in Iranian Patients with Behcet’s Disease
Single Nucleotide Polymorphisms of FCRL3 in Iranian Patients with Behcet’s Disease Open
Background: Both genetic and environmental factors influence, susceptibility to autoimmune disorders including Behcet’s disease (BD). FCRL3 (Fc receptor like 3 genes), a novel immunoregulatory gene, has recently been reported as a new prom…
View article: Effect of Nurse’s Characteristics on Their Willingness to Involve Patients in the Care Process in Hospitals in Tehran, Iran
Effect of Nurse’s Characteristics on Their Willingness to Involve Patients in the Care Process in Hospitals in Tehran, Iran Open
Introduction: Patient involvement in the care process is a widespread concept, which is considered an important issue to improve the quality of healthcare. This study aimed at assessing the effect of nurses’ characteristics on their willin…
View article: VAS910055 Supplemental Material - Supplemental material for Humoral and cellular immune response to Buerger’s disease
VAS910055 Supplemental Material - Supplemental material for Humoral and cellular immune response to Buerger’s disease Open
Supplemental material, VAS910055 Supplemental Material for Humoral and cellular immune response to Buerger’s disease by Seyed Morteza Ehteshamfar, Jalil Tavakkol Afshari, Mohammad-Hadi S. Modaghegh, Mahmoud Mahmoudi, Gholam Hosein Kazemzad…