Mahmoud Tarek Hefnawy
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View article: Maternal and paternal determinants of infant health: a cross-sectional study in four countries during the COVID-19 era
Maternal and paternal determinants of infant health: a cross-sectional study in four countries during the COVID-19 era Open
This study highlights the importance of socioeconomic factors, healthy parental lifestyle, and prenatal care in improving infant health outcomes. Public health initiatives should focus on promoting awareness of maternal health, early medic…
View article: Post-COVID-19 Cognitive Dysfunction: Analyzing the Role of Age, Lifestyle, and Neurological Impairments A Multi-Centric Case-Control Study
Post-COVID-19 Cognitive Dysfunction: Analyzing the Role of Age, Lifestyle, and Neurological Impairments A Multi-Centric Case-Control Study Open
Introduction The effects of COVID-19 extend beyond acute illness, with many survivors experiencing lingering symptoms. This study investigates the frequency and contributing factors of cognitive impairment and other neurological symptoms i…
View article: Efficacy and safety of edaravone dexborneol in acute ischemic stroke: systematic review and meta-analysis
Efficacy and safety of edaravone dexborneol in acute ischemic stroke: systematic review and meta-analysis Open
Background Edaravone dexborneol represents a novel neuroprotective agent utilized in the treatment of acute ischemic stroke (AIS). Preliminary studies indicate that this combination exhibits enhanced therapeutic effects when compared to th…
View article: Optimal duration of postoperative drainage following burr hole surgery for chronic subdural hematoma: A systematic review and network meta-analysis
Optimal duration of postoperative drainage following burr hole surgery for chronic subdural hematoma: A systematic review and network meta-analysis Open
View article: Safety and efficacy of Bruton’s tyrosine kinase inhibitors in multiple sclerosis: A systematic review and network meta-analysis of randomized controlled trials
Safety and efficacy of Bruton’s tyrosine kinase inhibitors in multiple sclerosis: A systematic review and network meta-analysis of randomized controlled trials Open
View article: Multimodal diagnostic tools and advanced data models for detection of prodromal Parkinson’s disease: a scoping review
Multimodal diagnostic tools and advanced data models for detection of prodromal Parkinson’s disease: a scoping review Open
Background Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. PD is diagnosed by a combination of motor symptoms including bradykine…
View article: Meta-analysis accelerator: a comprehensive tool for statistical data conversion in systematic reviews with meta-analysis
Meta-analysis accelerator: a comprehensive tool for statistical data conversion in systematic reviews with meta-analysis Open
Background Systematic review with meta-analysis integrates findings from multiple studies, offering robust conclusions on treatment effects and guiding evidence-based medicine. However, the process is often hampered by challenges such as i…
View article: Exploring the Mechanisms and Therapeutic Approaches of Mitochondrial Dysfunction in Alzheimer’s Disease: An Educational Literature Review
Exploring the Mechanisms and Therapeutic Approaches of Mitochondrial Dysfunction in Alzheimer’s Disease: An Educational Literature Review Open
View article: Cognitive impairment after tooth extraction: appraising literature and recommendations for future research
Cognitive impairment after tooth extraction: appraising literature and recommendations for future research Open
View article: Rigid ring vs. flexible band for tricuspid valve repair in patients with tricuspid valve regurgitation: A systematic review and meta-analysis
Rigid ring vs. flexible band for tricuspid valve repair in patients with tricuspid valve regurgitation: A systematic review and meta-analysis Open
Our study findings suggested no difference between rigid ring compared to flexible band regarding the rates of postoperative tricuspid regurgitation; however, rigid ring may encompass a higher bypass time. Therefore, further research is re…
View article: Prevalence and Clinical Characteristics of Sleeping Paralysis: A Systematic Review and Meta-Analysis
Prevalence and Clinical Characteristics of Sleeping Paralysis: A Systematic Review and Meta-Analysis Open
Sleep paralysis (SP) is a mixed state of consciousness and sleep, combining features of rapid eye movement (REM) sleep with those of wakefulness. The exact cause of SP is unknown, and its prevalence varies among the studies. We aim to iden…
View article: Efficacy and safety of intravenous mesenchymal stem cells for ischemic stroke patients, a systematic review and meta-analysis
Efficacy and safety of intravenous mesenchymal stem cells for ischemic stroke patients, a systematic review and meta-analysis Open
Background Clinical trials have evaluated the efficacy of intravenous mesenchymal stem cells (MSCs) for acute and subacute ischemic stroke. Therefore, we conducted this meta-analysis to investigate the efficacy and safety of intravenous MS…
View article: Appraising systematic reviews: a comprehensive guide to ensuring validity and reliability
Appraising systematic reviews: a comprehensive guide to ensuring validity and reliability Open
Systematic reviews play a crucial role in evidence-based practices as they consolidate research findings to inform decision-making. However, it is essential to assess the quality of systematic reviews to prevent biased or inaccurate conclu…
View article: Association of serum leptin and ghrelin levels with smoking status on body weight: a systematic review and meta-analysis
Association of serum leptin and ghrelin levels with smoking status on body weight: a systematic review and meta-analysis Open
Background and aims Smoking cigarettes is a major global health problem that affects appetite and weight. The aim of this systematic review was to determine how smoking affected plasma leptin and ghrelin levels. Methods A comprehensive sea…
View article: Comparative effects of minimally invasive approaches vs. conventional for obese patients undergoing aortic valve replacement: a systematic review and network meta-analysis
Comparative effects of minimally invasive approaches vs. conventional for obese patients undergoing aortic valve replacement: a systematic review and network meta-analysis Open
View article: Clinical assessment of liraglutide use in prediabetic and obese schizophrenic patients: A systematic literature review and meta-analysis
Clinical assessment of liraglutide use in prediabetic and obese schizophrenic patients: A systematic literature review and meta-analysis Open
Background and Hypothesis Schizophrenic patients are at a higher risk of developing prediabetes and obesity, which may increase their risk of cardiovascular and other diseases. Liraglutide, a glucagon-like peptide-1 receptor agonist, is ef…
View article: Glucagon-like peptide-1 receptor-agonists treatment for cardio-metabolic parameters in schizophrenia patients: a systematic review and meta-analysis
Glucagon-like peptide-1 receptor-agonists treatment for cardio-metabolic parameters in schizophrenia patients: a systematic review and meta-analysis Open
Aims We performed this meta-analysis to evaluate the efficacy and safety of glucagon-like peptide-1 receptor-agonists (GLP-1RA) treatment on cardio-metabolic parameters among antipsychotic-treated patients with schizophrenia. Methods We se…
View article: Utilidad del aprendizaje en línea con YouTube para los endoscopistas gastrointestinales junior: ¿Una práctica gratificante o disuasoria?
Utilidad del aprendizaje en línea con YouTube para los endoscopistas gastrointestinales junior: ¿Una práctica gratificante o disuasoria? Open
Antecedentes: La endoscopia es un campo competitivo en la práctica clínica en el que los endoscopistas calificados tienen una gran demanda. El proceso de aprendizaje para los endoscopistas gastrointestinales junior (JE) es difícil, bastant…
View article: Up-to-Date Review of Meningococcal Meningitis: Global Challenges and Recommendations
Up-to-Date Review of Meningococcal Meningitis: Global Challenges and Recommendations Open
The Center for Disease Control and Prevention is warning about a new outbreak of meningococcal meningitis among gay, bisexual, and other men that have sex with men (MSM) due to multiple cases reported in Florida. Meningococcal meningitis (…
View article: Xbb subvariant of Omicron: Can the new wave sneak past your immune defense?
Xbb subvariant of Omicron: Can the new wave sneak past your immune defense? Open
Since the emergence of coronavirus disease-2019 (COVID-19), many subvariants have emerged from the mother Omicron variant, such as the BA.4, BA.5, and the recent BA.2.751,2. Despite the reports of COVID-19 cases and deaths will have decrea…
View article: Could the Omicron BQ.1 sub-variant threaten to reverse the worldwide decline in COVID cases?
Could the Omicron BQ.1 sub-variant threaten to reverse the worldwide decline in COVID cases? Open
Dear Editor, The present evolution of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) pandemic has led to the emergence of several new Omicron sub-variants, including BA.2.75, BA.4.6, XBB, and BQ.1. Recently, more attentio…
View article: Clinical Characteristics, Course, and Outcomes of Vertebral Artery Dissections in the Postpartum Period; a Pooled Analysis of Published Case Reports.
Clinical Characteristics, Course, and Outcomes of Vertebral Artery Dissections in the Postpartum Period; a Pooled Analysis of Published Case Reports. Open
PPVAD is a severe medical condition but most cases were fully recovered after an early and proper antithrombotic plan for each case scenario.
View article: Could the New BA.2.75 Sub-Variant Cause the Emergence of a Global Epidemic of COVID-19? A Scoping Review
Could the New BA.2.75 Sub-Variant Cause the Emergence of a Global Epidemic of COVID-19? A Scoping Review Open
With over 58 million cases and 6 million deaths by August 2022, the Coronavirus disease 2019 (COVID-19), causing severe acute respiratory syndrome coronavirus 2 (SARs-CoV-2), has had an insurmountable impact on the world's population. This…
View article: Could the new BA.2.75 sub-variant lead to another COVID-19 wave in the world? – Correspondence
Could the new BA.2.75 sub-variant lead to another COVID-19 wave in the world? – Correspondence Open