Mahms Richard-Mohamed
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View article: Evaluating the Effects of Kidney Preservation at 10 °C with Hemopure and Sodium Thiosulfate in a Rat Model of Syngeneic Orthotopic Kidney Transplantation
Evaluating the Effects of Kidney Preservation at 10 °C with Hemopure and Sodium Thiosulfate in a Rat Model of Syngeneic Orthotopic Kidney Transplantation Open
Kidney transplantation is preferred for end-stage renal disease. The current gold standard for kidney preservation is static cold storage (SCS) at 4 °C. However, SCS contributes to renal graft damage through ischemia–reperfusion injury (IR…
View article: Static Cold Storage with Mitochondria-Targeted Hydrogen Sulfide Donor Improves Renal Graft Function in an Ex Vivo Porcine Model of Controlled Donation-after-Cardiac-Death Kidney Transplantation
Static Cold Storage with Mitochondria-Targeted Hydrogen Sulfide Donor Improves Renal Graft Function in an Ex Vivo Porcine Model of Controlled Donation-after-Cardiac-Death Kidney Transplantation Open
The global donor kidney shortage crisis has necessitated the use of suboptimal kidneys from donors-after-cardiac-death (DCD). Using an ex vivo porcine model of DCD kidney transplantation, the present study investigates whether the addition…
View article: The Impact of Nutritional Supplementation on Donor Kidneys During Oxygenated Ex Vivo Subnormothermic Preservation
The Impact of Nutritional Supplementation on Donor Kidneys During Oxygenated Ex Vivo Subnormothermic Preservation Open
Background. Evidence suggests that nutritional supplementation during normothermic ex vivo perfusion improves organ preservation. However, it is unclear whether the same benefit is observed during room temperature (subnormothermic) oxygena…
View article: Subnormothermic Perfusion with H2S Donor AP39 Improves DCD Porcine Renal Graft Outcomes in an Ex Vivo Model of Kidney Preservation and Reperfusion
Subnormothermic Perfusion with H2S Donor AP39 Improves DCD Porcine Renal Graft Outcomes in an Ex Vivo Model of Kidney Preservation and Reperfusion Open
Cold preservation is the standard of care for renal grafts. However, research on alternatives like perfusion at higher temperatures and supplementing preservation solutions with hydrogen sulfide (H2S) has gained momentum. In this study, we…
View article: MP52-01 EVALUATING THE EFFECT OF SUBNORMOTHERMIC PRESERVATION WITH HYDROGEN SULFIDE DONOR AP39 ON PORCINE DCD RENAL GRAFT OUTCOMES USING A NOVEL <i>EX VIVO</i> BLOOD-FREE MODEL OF KIDNEY PERFUSION
MP52-01 EVALUATING THE EFFECT OF SUBNORMOTHERMIC PRESERVATION WITH HYDROGEN SULFIDE DONOR AP39 ON PORCINE DCD RENAL GRAFT OUTCOMES USING A NOVEL <i>EX VIVO</i> BLOOD-FREE MODEL OF KIDNEY PERFUSION Open
You have accessJournal of UrologyTransplantation & Vascular Surgery: Renal Transplantation & Vascular Surgery II (MP52)1 Apr 2020MP52-01 EVALUATING THE EFFECT OF SUBNORMOTHERMIC PRESERVATION WITH HYDROGEN SULFIDE DONOR AP39 ON PORCINE DCD …
View article: Subnormothermic Oxygenated Perfusion Optimally Preserves Donor Kidneys Ex Vivo
Subnormothermic Oxygenated Perfusion Optimally Preserves Donor Kidneys Ex Vivo Open
Our novel study shows that oxygenated perfusion at near-room-temperature provides optimal donor kidney storage conditions.
View article: CORM-401 Reduces Ischemia Reperfusion Injury in an Ex Vivo Renal Porcine Model of the Donation After Circulatory Death
CORM-401 Reduces Ischemia Reperfusion Injury in an Ex Vivo Renal Porcine Model of the Donation After Circulatory Death Open
Carbon monoxide releasing molecules-401 provides renal protection after cold storage of kidneys and provides a novel clinically relevant ex vivo organ preservation strategy.