Mahsa Moein
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View article: l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain
l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain Open
Isomerization of l -aspartyl and l -asparaginyl residues to l -isoaspartyl residues is one type of protein damage that can occur under physiological conditions and leads to conformational changes, loss of function, and enhanced protein deg…
View article: CaSiAn: a Calcium Signaling Analyzer tool
CaSiAn: a Calcium Signaling Analyzer tool Open
Summary Ca2+ is a central second messenger in eukaryotic cells that regulates many cellular processes. Recently, we have indicated that typical Ca2+ signals are not purely oscillatory as widely assumed, but exhibit stochastic spiking with …
View article: On the phase space structure of IP3 induced Ca2+ signalling and concepts for predictive modeling
On the phase space structure of IP3 induced Ca2+ signalling and concepts for predictive modeling Open
The correspondence between mathematical structures and experimental systems is the basis of the generalizability of results found with specific systems and is the basis of the predictive power of theoretical physics. While physicists have …
View article: Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in <i>pink1</i><sup><i>−</i>/<i>−</i></sup> zebrafish
Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in <i>pink1</i><sup><i>−</i>/<i>−</i></sup> zebrafish Open
Mutations in PTEN ‐induced putative kinase 1 ( PINK 1 ) are a cause of early onset Parkinson's disease ( PD ). Loss of PINK 1 function causes dysregulation of mitochondrial calcium homeostasis, resulting in mitochondrial dysfunction and ne…