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Alteration of the Donor/Acceptor Spectrum of the (S)-Amine Transaminase from Vibrio fluvialis Open

Maika Genz, Clare Vickers, Tom van den Bergh, Henk‐Jan Joosten, Mark Dörr , et al. · 2015

To alter the amine donor/acceptor spectrum of an (S)-selective amine transaminase (ATA), a library based on the Vibrio fluvialis ATA targeting four residues close to the active site (L56, W57, R415 and L417) was created. A 3DM-derived alig…