Maike Gold
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View article: Data from Critical Role of Gα<sub>12</sub> and Gα<sub>13</sub> for Human Small Cell Lung Cancer Cell Proliferation <i>In vitro</i> and Tumor Growth <i>In vivo</i>
Data from Critical Role of Gα<sub>12</sub> and Gα<sub>13</sub> for Human Small Cell Lung Cancer Cell Proliferation <i>In vitro</i> and Tumor Growth <i>In vivo</i> Open
Purpose: In small cell lung cancer cells (SCLC), various autocrine stimuli lead to the parallel activation of Gq/11 and G12/13 proteins. Although the contribution of the Gq/11-phospholipase C-β casca…
View article: Supplementary Data from Critical Role of Gα<sub>12</sub> and Gα<sub>13</sub> for Human Small Cell Lung Cancer Cell Proliferation <i>In vitro</i> and Tumor Growth <i>In vivo</i>
Supplementary Data from Critical Role of Gα<sub>12</sub> and Gα<sub>13</sub> for Human Small Cell Lung Cancer Cell Proliferation <i>In vitro</i> and Tumor Growth <i>In vivo</i> Open
Supplementary Data from Critical Role of Gα12 and Gα13 for Human Small Cell Lung Cancer Cell Proliferation In vitro and Tumor Growth In vivo
View article: Supplementary Data from Critical Role of Gα<sub>12</sub> and Gα<sub>13</sub> for Human Small Cell Lung Cancer Cell Proliferation <i>In vitro</i> and Tumor Growth <i>In vivo</i>
Supplementary Data from Critical Role of Gα<sub>12</sub> and Gα<sub>13</sub> for Human Small Cell Lung Cancer Cell Proliferation <i>In vitro</i> and Tumor Growth <i>In vivo</i> Open
Supplementary Data from Critical Role of Gα12 and Gα13 for Human Small Cell Lung Cancer Cell Proliferation In vitro and Tumor Growth In vivo
View article: Data from Critical Role of Gα<sub>12</sub> and Gα<sub>13</sub> for Human Small Cell Lung Cancer Cell Proliferation <i>In vitro</i> and Tumor Growth <i>In vivo</i>
Data from Critical Role of Gα<sub>12</sub> and Gα<sub>13</sub> for Human Small Cell Lung Cancer Cell Proliferation <i>In vitro</i> and Tumor Growth <i>In vivo</i> Open
Purpose: In small cell lung cancer cells (SCLC), various autocrine stimuli lead to the parallel activation of Gq/11 and G12/13 proteins. Although the contribution of the Gq/11-phospholipase C-β casca…
View article: <scp>IGF1R</scp> expression by adult oligodendrocytes is not required in the steady‐state but supports neuroinflammation
<span>IGF1R</span> expression by adult oligodendrocytes is not required in the steady‐state but supports neuroinflammation Open
In the central nervous system (CNS), insulin‐like growth factor 1 (IGF‐1) regulates myelination by oligodendrocyte (ODC) precursor cells and shows anti‐apoptotic properties in neuronal cells in different in vitro and in vivo systems. Previ…
View article: 549 An RNA-lipoplex (RNA-LPX) vaccine demonstrates strong immunogenicity and promising clinical activity in a Phase I trial in cutaneous melanoma patients with no evidence of disease at trial inclusion
549 An RNA-lipoplex (RNA-LPX) vaccine demonstrates strong immunogenicity and promising clinical activity in a Phase I trial in cutaneous melanoma patients with no evidence of disease at trial inclusion Open
Background Lipo-MERIT is an ongoing, first-in-human, open-label, dose-escalation Phase I trial investigating safety, tolerability and immunogenicity of BNT111 in patients with advanced melanoma. BNT111 is an RNA-LPX vaccine targeting the m…
View article: Das Büro als Produkt und Prozess / The Office as Product and Process
Das Büro als Produkt und Prozess / The Office as Product and Process Open
View article: A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles encoding shared tumor antigens for immunotherapy of malignant melanoma
A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles encoding shared tumor antigens for immunotherapy of malignant melanoma Open
Background: Local therapeutic vaccination with tumor antigen-encoding mRNAs is being investigated in various clinical trials. We have developed a novel class of RNA-lipoplex (RNA(LIP)) immunotherapeutics for intravenous application allowin…
Extending the functional characteristics of naturally occurring autoantibodies against β-Amyloid, Prion Protein and α-Synuclein Open
View article: β-amyloid, microglia, and the inflammasome in Alzheimer’s disease
β-amyloid, microglia, and the inflammasome in Alzheimer’s disease Open
View article: Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson’s Disease
Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson’s Disease Open
These data may open a new field in the diagnosis of neurodegenerative disease such as Alzheimer's disease and Parkinson's disease. Further research is required to evaluate the significance of these pulmonary findings with respect to the pa…